13,389 research outputs found
Results from a Second RXTE Observation of the Coma Cluster
The RXTE satellite observed the Coma cluster for 177 ksec during November and
December 2000, a second observation motivated by the intriguing results from
the first 87 ksec observation in 1996. Analysis of the new dataset confirms
that thermal emission from isothermal gas does not provide a good fit to the
spectral distribution of the emission from the inner 1 degree radial region.
While the observed spectrum may be fit by emission from gas with a substantial
temperature gradient, it is more likely that the emission includes also a
secondary non-thermal component. If so, non-thermal emission comprises ~8% of
the total 4--20 keV flux. Interpreting this emission as due to Compton
scattering of relativistic electrons (which produce the known extended radio
emission) by the cosmic microwave background radiation, we determine that the
mean, volume-averaged magnetic field in the central region of Coma is B =
0.1-0.3 microgauss.Comment: 10 pages, 1 figure; APJ, in pres
Single-Molecule AFM Studies of Substrate Transport by Using the Sodium-Glucose Cotransporter SGLT1
Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis.
Background: Recent evidence suggests that distinction
of subsets of rheumatoid arthritis (RA) depending on anticyclic
citrullinated peptide antibody (anti-CCP) status may
be helpful in distinguishing distinct aetiopathologies and in
predicting the course of disease. HLA-DRB1 shared
epitope (SE) and peptidylarginine deiminase type 4
(PADI4) genotype, both of which have been implicated in
anti-CCP generation, are assumed to be associated with
RA.
Objectives: To elucidate whether PADI4 affects the
clinical characteristics of RA, and whether it would
modulate the effect of anti-CCPs on clinical course. The
combined effect of SE and PADI4 on autoantibody profile
was also analysed.
Methods: 373 patients with RA were studied. SE,
padi4_94C.T, rheumatoid factor, anti-CCPs and antinuclear
antibodies (ANAs) were determined. Disease
severity was characterised by cumulative therapy
intensity classified into ordinal categories (CTI-1 to CTI-3)
and by Steinbrocker score.
Results: CTI was significantly associated with disease
duration, erosive disease, disease activity score (DAS) 28
and anti-CCPs. The association of anti-CCPs with CTI was
considerably influenced by padi4_94C.T genotype (C/C:
ORadj=0.93, padj=0.92; C/T: ORadj=2.92,
padj=0.093; T/T: ORadj=15.3, padj=0.002). Carriage of
padi4_94T exhibited a significant trend towards higher
Steinbrocker scores in univariate and multivariate
analyses. An association of padi4_94C.T with ANAs
was observed, with noteworthy differences depending on
SE status (SE2: ORadj=6.20, padj,0.04; SE+:
ORadj=0.36, padj=0.02) and significant heterogeneity
between the two SE strata (p=0.006).
Conclusions: PADI4 genotype in combination with anti-
CCPs and SE modulates clinical and serological characteristics
of RA
Langevin equation for the extended Rayleigh model with an asymmetric bath
In this paper a one-dimensional model of two infinite gases separated by a
movable heavy piston is considered. The non-linear Langevin equation for the
motion of the piston is derived from first principles for the case when the
thermodynamic parameters and/or the molecular masses of gas particles on left
and right sides of the piston are different. Microscopic expressions involving
time correlation functions of the force between bath particles and the piston
are obtained for all parameters appearing in the non-linear Langevin equation.
It is demonstrated that the equation has stationary solutions corresponding to
directional fluctuation-induced drift in the absence of systematic forces. In
the case of ideal gases interacting with the piston via a quadratic repulsive
potential, the model is exactly solvable and explicit expressions for the
kinetic coefficients in the non-linear Langevin equation are derived. The
transient solution of the non-linear Langevin equation is analyzed
perturbatively and it is demonstrated that previously obtained results for
systems with the hard-wall interaction are recovered.Comment: 10 pages. To appear in Phys. Rev.
Trailing Edge Noise Reduction by Passive and Active Flow Controls
This paper presents the results on the use of porous metal foams (passive control) and dielectric barrier surface plasma actuations (active control) for the reduction of vortex shedding tonal noises from the nonflat plate type trailing edge serration in a NACA0012 airfoil previously discussed in Chong et al. (AIAA J. Vol. 51, 2013, pp. 2665-2677). The use of porous metal foams to fill the interstices between adjacent members of the sawtooth can almost completely suppress the vortex shedding tonal noise, whilst the serration effect on the broadband noise reduction is retained. This concept will promote the nonflat plate type serrated trailing edge to become a genuine alternative to the conventional flat plate type serrated trailing edge, which is known to have drawbacks in the structural stability, aerodynamic performances and implementation issues. For the plasma actuators, configuration which produces electric wind in a tangential direction is found to be not very effective in suppressing the vortices emanated from the serration blunt root. On the other hand, for the plasma configuration which produces electric wind in a vertical direction, good level of vortex shedding tonal noise reduction has been demonstrated. However, the self noise produced by the plasma actuators negates the noise benefits on the tonal noise reduction. This characteristic illustrates the need to further develop the plasma actuators in a two pronged approach. First is to increase the electric wind speed, thereby allowing the plasma actuators to be used in a higher free jet velocity which naturally produces a larger level of jet noise. Second, the self noise radiated by the plasma actuators should be reduced
On the Second Law of thermodynamics and the piston problem
The piston problem is investigated in the case where the length of the
cylinder is infinite (on both sides) and the ratio is a very small
parameter, where is the mass of one particle of the gaz and is the mass
of the piston. Introducing initial conditions such that the stochastic motion
of the piston remains in the average at the origin (no drift), it is shown that
the time evolution of the fluids, analytically derived from Liouville equation,
agrees with the Second Law of thermodynamics.
We thus have a non equilibrium microscopical model whose evolution can be
explicitly shown to obey the two laws of thermodynamics.Comment: 29 pages, 9 figures submitted to Journal of Statistical Physics
(2003
The 5-kW arcjet power electronics
The initial design and evaluation of a 5 kW arcjet power electronics breadboard which as been integrated with a modified 1 kW design laboratory arcjet is presented. A single stage, 5 kW full bridge, pulse width modulated (PWM), power converter was developed which was phase shift regulated. The converter used metal oxide semiconductor field effect transistor (MOSFET) power switches and incorporated current mode control and an integral arcjet pulse ignition circuit. The unoptimized power efficiency was 93.5 and 93.9 percent at 5 kW and 50A output at input voltages of 130 and 150V, respectively. Line and load current regulation at 50A output was within one percent. The converter provided up to 6.6 kW to the arcjet with simulated ammonia used as a propellant
A Robust Iterative Unfolding Method for Signal Processing
There is a well-known series expansion (Neumann series) in functional
analysis for perturbative inversion of specific operators on Banach spaces.
However, operators that appear in signal processing (e.g. folding and
convolution of probability density functions), in general, do not satisfy the
usual convergence condition of that series expansion. This article provides
some theorems on the convergence criteria of a similar series expansion for
this more general case, which is not covered yet by the literature.
The main result is that a series expansion provides a robust unbiased
unfolding and deconvolution method. For the case of the deconvolution, such a
series expansion can always be applied, and the method always recovers the
maximum possible information about the initial probability density function,
thus the method is optimal in this sense. A very significant advantage of the
presented method is that one does not have to introduce ad hoc frequency
regulations etc., as in the case of usual naive deconvolution methods. For the
case of general unfolding problems, we present a computer-testable sufficient
condition for the convergence of the series expansion in question.
Some test examples and physics applications are also given. The most
important physics example shall be (which originally motivated our survey on
this topic) the case of pi^0 --> gamma+gamma particle decay: we show that one
can recover the initial pi^0 momentum density function form the measured single
gamma momentum density function by our series expansion.Comment: 23 pages, 9 figure
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