278 research outputs found
Estudio multidisciplinar de seguimiento del peso corporal en una cohorte de pacientes en tratamiento inicial con antipsicóticos
Introduction. El aumento de peso es una de las reacciones adversas más preocupantes de los antipsicóticos atípicos por el riesgo cardiovascular que entraña, entre otros aspectos. El objetivo principal es conocer la evolución del peso e índice de masa corporal a los 6 meses asociada al tratamiento inicial con antipsicóticos en condiciones reales de uso. Métodos. Estu- dio de cohortes, multicéntrico y prospectivo. Resultados. Se ha reclutado una cohorte de 71 pacientes tratados con antipsicóticos (mediana=54 años). Un 60% de pacientes muestra un incremento de peso al finalizar el periodo de seguimiento. En los hombres (32%, mediana=37 años), se obtuvo que el peso corporal medio inicial fue 74, 9 kg (DE=15,4) y final 81,1 kg (DE=16,7); el índice masa corporal medio inicial 25, 1 kg/m2 (DE=4,2) y final 27,1 kg/m2 (DE=4,6). En las mujeres (68%, mediana=61,5 años), se obtuvo que el peso corporal medio inicial fue 61, 4 kg (DE=10,0) y final 63, 0 kg (DE=11,2); el índice masa corporal medio inicial 26, 6 kg/m2 (DE=4,9) y final 27,0 kg/m2 (DE=4,6). El aumento de 2 o más kg de peso es signi- ficativamente mayor en menores de 55 años, así como en hombres. Conclusiones. El inicio de tratamiento con un antipsicótico en condiciones reales de uso se asocia a incremento de peso e índice de masa corporal de los pacientes a los 6 meses, tanto en hombres como mujeres. Se ha constituído un grupo de investigación multidisciplinar centrado en el estudio del uso de antipsicóticos.Introduction. Weight gain is one of the most troubling adverse effects of atypical anti- psychotics due to their cardiovascular risk and other factors. The main objective is to assess possible changes of body weight and body mass index at 6 months associated with onset of antipsychotic treatment in ordinary clinical use. Methods. It's a cohort, multicentre, prospective study. Results. A cohort of 71 patients treated with antipsychotics was recruited (median=54 years). A total of 60% of patients showed an increase of body weight at the end of the follow- up period. In males (32%, median=37 years), it was obtained that mean body weight at base- line was 74, 9 kg (DE=15,4)and at 6 months 81,1 kg (DE=16,7); mean body mass index at baseline was 25,1 kg/m2 (DE=4,2) and at 6 months 27,1 kg/m2 (DE=4,6). In women (68%, median=61,5 years), it was obtained that mean body weight at baseline was 61,4 kg (DE=10,0) and at 6 months 63, 0 kg (DE=11,2); mean body mass index at baseline 26,6 kg/m2 (DE=4,9) and at 6 months 27,0 kg/m2 (DE=4,6). Increase of body weight over 2 kg was significantly higher in patients under 55 years and males. Conclusions. Onset of antipsychotic treatment in ordinary clinical use is associated with an increase of patients' body weight and body mass index at 6 months, both for men and women. A multidisciplinary research team focused on the study of antipsychotic use of has been established
Random phase approximation for multi-band Hubbard models
We derive the random-phase approximation for spin excitations in general
multi-band Hubbard models, starting from a collinear ferromagnetic Hartree-Fock
ground state. The results are compared with those of a recently introduced
variational many-body approach to spin-waves in itinerant ferromagnets. As we
exemplify for Hubbard models with one and two bands, the two approaches lead to
qualitatively different results. The discrepancies can be traced back to the
fact that the Hartree-Fock theory fails to describe properly the local moments
which naturally arise in a correlated-electron theory.Comment: 25 pages, 2 figure
Energy Efficient Content Distribution in an ISP Network
International audienceWe study the problem of reducing power consump- tion in an Internet Service Provider (ISP) network by designing the content distribution infrastructure managed by the operator. We propose an algorithm to optimally decide where to cache the content inside the ISP network. We evaluate our solution over two case studies driven by operators feedback. Results show that the energy-efficient design of the content infrastructure brings substantial savings, both in terms of energy and in terms of bandwidth required at the peering point of the operator. Moreover, we study the impact of the content characteristics and the power consumption models. Finally, we derive some insights for the design of future energy-aware networks
Capacitação dos agentes comunitários de saúde na Estratégia Saúde da Família Morretes III do município de Itapema-SC
Com o início da atuação do PACS/PSF, uma nova dinâmica de trabalho foi estruturada a partir das unidades básicas. Passaram a ser criadas estratégias para oferecer atenção integral à saúde da comunidade, focando no indivíduo, na família e em grupos específicos. Para atingir este objetivo, faz-se necessário reconhecer fatores de risco aos quais a população está exposta e, a partir disto, desenvolver projetos interdisciplinares para criar soluções. Por fazer parte e estar inserido no dia a dia da comunidade local, o agente comunitário de saúde (ACS) mantem contato permanente com as famílias, facilitando o trabalho de vigilância e promoção a saúde e, para isso, deve-se ter uma postura de liderança frente a população. O projeto tem como objetivo aprimorar o acolhimento à população e a atuação dos Agentes Comunitários de Saúde da ESF Morretes III, em Itapema-SC, realizando treinamento da equipe sobre problemas cotidianos apresentados pela população, formas de atuação e detecção de riscos e melhorando as técnicas de abordagem frente a situações-problema. Após serem identificados os assuntos que geram mais dúvidas entre as ACSs, selecionamos aqueles em que julgamos haver maior prioridade. De acordo com este levantamento, foram introduzidas as primeiras palestras e atividades. Os encontros foram realizados mensalmente com participação de profissionais do NASF. Ao final dos encontros as participantes realizavam avaliações, através das quais foi possível reforçar os pontos positivos e corrigir algumas falhas. Incluir na formação dos ACSs conhecimentos sobre o processo saúde-doença, incluindo os aspectos biológicos, econômicos, sociais e culturais é essencial para transformá-los em sujeitos proativos e alcançar os objetivos do programa. Este contato direto permite um elo entre o saber científico e o saber popular, aproximando a equipe atuante na área, da comunidade
Hydrogen bonded anion ribbons, networks and clusters and sulfur–anion interactions in novel radical cation salts of BEDT-TTF with sulfamate, pentaborate and bromide
Estudio de factibilidad para la producción, y comercialización de chirimoya (Annona cherimola Mil), Ecotipo T61 Tumbaco- Pichincha.
This project is a feasibility study for the production and marketing of cherimoya
(Annona cherimola Mil) and the use of a new improved genetic material, more
productive, ecotype T61 Tumbaco. This fruit crop is produced in the valleys of
Imbabura, Pichincha, Azuay, and Loja, having favorable climatic and soil
conditions. Market research indicates that in Ecuador there is an unsatisfied
demand for domestic consumption. A survey involving the farmers of the Quito
area revealed the reasons why cherimoya supply has not increased, whereas a
consumer survey confirmed the estimate that consumption does not meet
demand due to lack of regular production throughout the year. The technical
study provides information on good practices, such as the handling of planting
density, formation, fruiting and rejuvenation pruning, hand pollination to
increase the number of flowers pollinated, pest control, limited to the control of
fruit fly (Anastrepha sp) and the application of appropriate techniques in the
collection, fruit selection, storage, packaging and delivery to retailer or
consumer. All these practices aim to improve farmer income and, therefore,
increase the profitability of the operation. The project includes implementation of
four hectares of land and an initial fruit yield of 15,000 kilograms of fruit per
hectare (60,000 kilograms in four hectares) from the third year on, with an
annual increase of 1,000 kilograms per hectare. The expected revenues were
estimated with a selling price of 130,270.48 to be financed 70%
by a bank loan and 30% equity. Both, Internal Rate of Return IRR (21%) and
the net present value NPV (78,985.73), represents approximately 40% of the expected total income
(3 por kilo de producto y ajustes en los años subsecuentes de 8%
anual en compensación a la inflación. En el estudio financiero se ha
considerado una inversión inicial de 123,270.93 )
y la relación Beneficio/ Costo B/C (4.42) demuestran la viabilidad financiera
del proyecto. El cálculo del punto de equilibrio señala que el ingreso
necesario para no perder ni ganar al tercer año (180,000)
The potential impact of entrepreneurship education on doctoral students within the non-commercial research environment in Chile
Chilean doctoral programs in science and technology generally do not consider entrepreneurial training within their curricula. Taking an entrepreneurial competency approach, we explore the potential impact of introducing an entrepreneurship education course to doctoral students based within a non-commercial research environment. We identified two main areas of possible impact: the potential effects upon doctoral research projects and the potential effects upon the doctoral students themselves. We followed the learning experiences of science and technology PhD students before, during, and a year after an entrepreneurial course through a multiple case study research design. Our results suggest that entrepreneurship education has a positive impact upon the development of student's creative problem solving and communication skills. This was reported to have a generally positive effect upon the students' doctoral projects and on the student's self-efficacy and entrepreneurial intentions. We conclude that entrepreneurship education complements traditional doctoral training for students within a non commercial academic setting
Conditions de la condensation de Knoevenagel–Cope pour la synthèse de cétones α,β-éthyléniques
El liderazgo del director y su influencia en la gestión pedagógica de los docentes de las instituciones educativas de la RED No. 04 UGEL No. 02, distrito de Independencia, 2013
La presente investigación tiene como objetivo general determinar la influencia del
liderazgo del director en la gestión pedagógica de los docentes de las Instituciones
Educativas de la RED Nº 04 UGEL N° 02, distrito de Independencia, 2013.
La investigación obedece a un tipo de investigación explicativo, cuyo diseño de
estudio es una investigación no experimental transeccional correlacional causal,
que utiliza el enfoque cuantitativo, el instrumento utilizado es un cuestionario de 42
ítems para la variable liderazgo directivo y de 36 ítems para la variable gestión
pedagógica, la que ha sido aplicada a una muestra de 23 directivos y 193 docentes
de las instituciones educativas de la RED Nº 04 UGEL N° 02, distrito de
Independencia. El procesamiento estadístico descriptivo e inferencial se realizó con
el paquete estadístico SPSS V-20 en español.
La conclusión a la que se llega es: Mediante la prueba de regresión simple se
determinó que el R2 fue de 0,037 (3.7% ), esto implica que el liderazgo del director
no influyó sobre la gestión pedagógica de los docentes de las Instituciones
Educativas de la RED Nº 04 UGEL N° 02, distrito de independencia. Además este
resultado estadísticamente no es significativo para (ρ =,316 > ,05). En cambio en la
parte descriptiva se demuestra que, el liderazgo del director es eficiente en un
56.5%, mientras que el 30.4% consideran que el liderazgo del director es
ineficiente, de la misma manera el 55.4% de los sujetos consideran que la gestión
pedagógica de los docentes es regular y el 38.9% consideran que la gestión
pedagógica de los docentes es bueno
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