201 research outputs found

    Continuous Finite-Time Stabilization of the Translational and Rotational Double Integrators

    Get PDF
    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/57800/1/BhatFTSDoubleIntegIEEETAC1998.pd

    Adaptive control of uncertain nonholonomic systems in finite time

    Get PDF
    summary:In this paper, the finite-time stabilization problem of chained form systems with parametric uncertainties is investigated. A novel switching control strategy is proposed for adaptive finite-time control design with the help of Lyapunov-based method and time-rescaling technique. With the proposed control law, the uncertain closed-loop system under consideration is finite-time stable within a given settling time. An illustrative example is also given to show the effectiveness of the proposed controller

    Dual – loop force – displacement mixed control strategy and its application on the quasi – static test

    Get PDF
    The Quasi-static test is a well-known powerful methodology to evaluate the seismic performance of structural components and systems. One of the most important challenges in the Quasi-static testing is to achieve precise boundary conditions, especially for the axial loading of vertical components. The requirement of synchronized displacement loading and target axial force formed a pair of contradiction. A dual-loop force-displacement mixed control strategy is proposed. The presented approach is successfully verified through the quasi-static testing for a full-scale concrete filled steel tube column. The control targets are achieved with an excellent control performance

    CT-BERT: Learning Better Tabular Representations Through Cross-Table Pre-training

    Full text link
    Tabular data -- also known as structured data -- is one of the most common data forms in existence, thanks to the stable development and scaled deployment of database systems in the last few decades. At present however, despite the blast brought by large pre-trained models in other domains such as ChatGPT or SAM, how can we extract common knowledge across tables at a scale that may eventually lead to generalizable representation for tabular data remains a full blank. Indeed, there have been a few works around this topic. Most (if not all) of them are limited in the scope of a single table or fixed form of a schema. In this work, we first identify the crucial research challenges behind tabular data pre-training, particularly towards the cross-table scenario. We position the contribution of this work in two folds: (i)-we collect and curate nearly 2k high-quality tabular datasets, each of which is guaranteed to possess clear semantics, clean labels, and other necessary meta information. (ii)-we propose a novel framework that allows cross-table pre-training dubbed as CT-BERT. Noticeably, in light of pioneering the scaled cross-table training, CT-BERT is fully compatible with both supervised and self-supervised schemes, where the specific instantiation of CT-BERT is very much dependent on the downstream tasks. We further propose and implement a contrastive-learning-based and masked table modeling (MTM) objective into CT-BERT, that is inspired from computer vision and natural language processing communities but sophistically tailored to tables. The extensive empirical results on 15 datasets demonstrate CT-BERT's state-of-the-art performance, where both its supervised and self-supervised setups significantly outperform the prior approaches

    An extensive anoxic event in the Triassic of the South China Block : a pyrite framboid study form Dajiang and its implications for the cause(s) of oxygen depletion

    Get PDF
    Water column oxygen deficiency has been considered as a potent driver of the extinction of marine benthos, and is a main feature of marine environments in the aftermath of the end-Permian mass extinction. The record of Permian-Triassic anoxia is more complex than previously thought, and is seen to vary between different palaeogeographic settings, but a full understanding is hindered by a paucity of evidence. During the Permian-Triassic interval the South China Block was located equatorially with Palaeotethys to the north and western Panthalassa to the south. This specific configuration provides a unique opportunity to compare the extent and duration of oxygen deficiency in Palaeotethys and Panthalassa under broadly similar climatic conditions. Sedimentary facies and pyrite framboid size-frequency distributions suggest that the oxygen-poor conditions became widespread across the shallow-marine carbonate platform of the South China Block immediately above the Permian-Triassic boundary and mass extinction level. Oxygen deficiency was most intense at the southern margin of the block where it met Panthalassa. Proposed drivers of the expansion of oxygen minimum zones into platform settings include enhanced terrigenous input and/or ocean stratification, or alternatively the upwelling of nutrient-rich deep ocean water. The former mechanisms are theoretically more likely to have operated in the relatively restricted Palaeotethys which was surrounded by ancient lands. In contrast, Panthalassa would likely have experienced stronger oceanic circulation and therefore be more susceptible to the effects of upwelling. Although variations in the record of the South China Block anoxic event might reflect local factors, the greater intensity of oxygen deficiency and a concomitant larger negative shift in carbonate carbon isotopes on its Panthalassan margin point to a key role for upwelling. This mechanism was likely a major driver of the Permian-Triassic global oceanic anoxic event, which itself was at least partly responsible for the ongoing inhospitable conditions and delayed recovery following the end-Permian extinction

    Molecular cloning and expression profiles of MnSOD and CAT genes from the turbot <em>Scophthalmus maximus</em>

    Get PDF
    Manganese superoxide dismutase (MnSOD) and catalase (CAT) could eliminate reactive oxygen species (ROS) and maintain the reduction-oxidation balance in cells. This study aimed to investigate their functions in turbot (Scophthalmus maximus) response to the *Vibro anguillarum* challenge. SmMnSOD, the full-length liver cDNA of MnSOD from *S. maximus*, was cloned by fast amplification of cDNA ends (RACE). Sequencing of nucleotides indicated that the SmMnSOD cDNA was 1267 base pairs with a 684-base-pair open reading frame, encoding a 228 amino acid protein with 28 amino acid residues. The SmMnSOD sequence contains MnSOD signatures (DVWEHAYY) and probable N-glycosylation sites (NVT, NHT, and NLS). The deduced sequence of SmMnSOD revealed sequence homology between 85.3% and 92.9% with those of other species. A phylogenetic study found that SmMnSOD clustered with other fish MnSOD, indicating that SmMnSOD was a member of the MnSOD family. The SmMnSOD transcript was discovered by qRT-PCR in the gill, stomach, head-kidney, muscle, liver, intestine, and heart of *S. maximus*, with the highest expression in the liver. Upon intervention by *V. anguillarum*, the liver and head kidney transcript levels of SmMnSOD were up-regulated at 12 and 48 h, whereas the temporal expression profiles of the CAT transcript increased at 6 and 24 h. As the pathogenic bacterial stress processing was prolonged to 72 h, the liver and head kidney transcript levels of SmMnSOD and CAT decreased gradually. Thus, SmMnSOD was triggered and may be related to *S. maximus*' immunological responses against *V. anguillarum*

    Causal role of immune cells in bipolar disorder: a Mendelian randomization study

    Get PDF
    BackgroundThe understanding of the immunological mechanisms underlying bipolar disorder (BD) has enhanced in recent years due to the extensive use of high-density genetic markers for genotyping and advancements in genome-wide association studies (GWAS). However, studies on the relationship between immune cells and the risk of BD remain limited, necessitating further investigation.MethodsBidirectional two-sample Mendelian Randomization (MR) analysis was employed to investigate the causal association between immune cell morphologies and bipolar disorder. Immune cell traits were collected from a research cohort in Sardinia, whereas the GWAS summary statistics for BD were obtained from the Psychiatric Genomics Consortium. Sensitivity analyses were conducted, and the combination of MR-Egger and MR-Presso was used to assess horizontal pleiotropy. Cochran’s Q test was employed to evaluate heterogeneity, and the results were adjusted for false discovery rate (FDR).ResultsThe study identified six immune cell phenotypes significantly associated with BD incidence (P&lt; 0.01). These phenotypes include IgD- CD27- %lymphocyte, CD33br HLA DR+ CD14- AC, CD8 on CD28+ CD45RA+ CD8br, CD33br HLA DR+ AC, CD14 on CD14+ CD16+ monocyte, and HVEM on CD45RA- CD4+. After adjusting the FDR to 0.2, two immune cell phenotypes remained statistically significant: IgD-CD27-% lymphocyte (OR=1.099, 95% CI: 1.051-1.149, P = 3.51E-05, FDR=0.026) and CD33br HLA DR+ CD14-AC (OR=0.981, 95% CI: 0.971-0.991, P = 2.17E-04, FDR=0.079). In the reverse MR analysis, BD significantly impacted the phenotypes of four monocytes (P&lt; 0.01), including CD64 on CD14+ CD16+ monocyte, CD64 on monocyte, CX3CR1 on CD14- CD16-, CD64 on CD14+ CD16- monocyte. However, after applying the FDR correction (FDR &lt; 0.2), no statistically significant results were observed.ConclusionsThis MR investigation reveals associations between immune cell phenotypes, bipolar disorder, and genetics, providing novel perspectives on prospective therapeutic targets for bipolar disorder

    Complete Mitogenome sequencing of the fish louse Argulus japonicus (Crustacea: Branchiura): Comparative analyses and phylogenetic implications

    Get PDF
    The fish louse Argulus japonicus, a branchiuran crustacean of the Argulidae family, is attracting increasing attention because of its parasitic tendencies and significant health threats to global fish farming. The mitogenomes can yield a foundation for studying epidemiology, genetic diversity, and molecular ecology and therefore may be used to assist in the surveillance and control of A. japonicus. In this study, we sequenced and assembled the complete mitogenome of A. japonicus to shed light on its genetic and evolutionary blueprint. Our investigation indicated that the 15,045-bp circular genome of A. japonicus encodes 13 protein-coding genes (PCGs), 22 transfer RNAs (tRNAs), and 2 ribosomal RNAs (rRNAs) with significant AT and GC skews. Comparative genomics provided an evolutionary scenario for the genetic diversity of 13 PCGs: all were under purifying selection, with cox1 and nad6 having the lowest and highest evolutionary rates, respectively. Genome-wide phylogenetic trees established a close relationship between species of the families Argulidae (Arguloida) and Armilliferidae (Porocephalida) within Crustacea, and further, A. japonicus and Argulus americanus were determined to be more closely related to each other than to others within the family Argulidae. Single PCG-based phylogenies supported nad1 and nad6 as the best genetic markers for evolutionary and phylogenetic studies for branchiuran crustaceans due to their similar phylogenetic topologies with those of genome-based phylogenetic analyses. To sum up, these comprehensive mitogenomic data of A. japonicus and related species refine valuable marker resources and should contribute to molecular diagnostic methods, epidemiological investigations, and ecological studies of the fish ectoparasites in Crustacea
    corecore