Lithographic Vertical-cavity Surface-emitting Lasers

Remarkable improvements in vertical-cavity surface-emitting lasers (VCSELs) have been made by the introduction of mode- and current-confining oxide optical aperture now used commercially. However, the oxide aperture blocks heat flow inside the device, causing a larger thermal resistance, and the internal strain caused by the oxide can degrade device reliability, also the diffusion process used for the oxide formation can limit device uniformity and scalability. Oxide-free lithographic VCSELs are introduced to overcome these device limitations, with both the mode and current confined within the lithographically defined intracavity mesa, scaling and mass production of small size device could be possible. The 3 μm diameter lithographic VCSEL shows a threshold current of 260 μA, differential quantum efficiency of 60% and maximum output power density of 65 kW/cm2 , and shows single-mode singlepolarization operation with side-mode-suppression-ratio over 25 dB at output power up to 1 mW. The device also shows reliable operation during 1000 hours stress test with high injection current density of 142 kA/cm2 . The lithographic VCSELs have much lower thermal resistance than oxide-confined VCSELs due to elimination of the oxide aperture. The improved thermal property allows the device to have wide operating temperature range of up to 190 °C heat sink temperature, high output power density especially in small device, high rollover current density and high rollover cavity temperature. Research is still underway to reduce the operating voltage of lithographic VCSELs for high wall plug efficiency, and the voltage of 6 µm device at injection current density of 10 kA/cm2 is reduces to 1.83 V with optimized mesa and DBR mirror iv structure. The lithographic VCSELS are promising to become the next generation VCSEL technology

The role of TcdB and TccC subunits in secretion of the photorhabdus Tcd toxin complex

The Toxin Complex (TC) is a large multi-subunit toxin encoded by a range of bacterial pathogens. The best-characterized examples are from the insect pathogens Photorhabdus, Xenorhabdus and Yersinia. They consist of three large protein subunits, designated A, B and C that assemble in a 5:1:1 stoichiometry. Oral toxicity to a range of insects means that some have the potential to be developed as pest control technology. The three subunit proteins do not encode any recognisable export sequences and as such little progress has been made in understanding their secretion. We have developed heterologous TC production and secretion models in E. coli and used them to ascribe functions to different domains of the crucial B+C sub-complex. We have determined that the B and C subunits use a secretion mechanism that is either encoded by the proteins themselves or employ an as yet undefined system common to laboratory strains of E. coli. We demonstrate that both the N-terminal domains of the B and C subunits are required for secretion of the whole complex. We propose a model whereby the N-terminus of the C-subunit toxin exports the B+C sub-complex across the inner membrane while that of the B-subunit allows passage across the outer membrane. We also demonstrate that even in the absence of the B-subunit, that the C-subunit can also facilitate secretion of the larger A-subunit. The recognition of this novel export system is likely to be of importance to future protein secretion studies. Finally, the identification of homologues of B and C subunits in diverse bacterial pathogens, including Burkholderia and Pseudomonas, suggests that these toxins are likely to be important in a range of different hosts, including man

Synthesis of Boron Nitride Nanotubes by Self-Propagation High-Temperature Synthesis and Annealing Method

High-quality boron nitride nanotubes were synthesized by annealing porous precursor in flowing NH3 gas at 1150°C. The porous precursor B18Ca2(MgO)9 was produced by self-propagation high-temperature synthesis (SHS) method using Mg, B2O3, and CaB6 as the starting materials, which played an important role in synthesis of BN nanotubes in large quantities. Samples were characterized by SEM, TEM, EDX, HRTEM, X-ray powder diffraction (XRD), Raman, and Fourier transform infrared (FTIR) spectroscopy. The as-synthesized BN nanotubes have an average diameter of about 150 nm with a wall/diameter ratio of 2/3. Mean length of the BN nanotubes was more than 10 μm. The effects of temperature, time, and the possible mechanism of the growth of the BN nanotubes were also discussed