Influenza A nucleoprotein binding sites for antivirals: current research and future potential

This document is the Accepted Manuscript version of the following article: Andreas Kukol and Hershna Patel, ‘Influenza A nucleoprotein binding sites for antivirals: current research and future potential’, Future Biology, Vol 9(7): 625-627, July 2014. The version of record is available online at doi: 10.2217/fvl.14.45Peer reviewedFinal Accepted Versio

How to capture active particles

For many applications, it is important to catch collections of autonomously navigating microbes and man-made microswimmers in a controlled way. Here we propose an efficient trap to collectively capture self-propelled colloidal rods. By means of computer simulation in two dimensions, we show that a static chevron-shaped wall represents an optimal boundary for a trapping device. Its catching efficiency can be tuned by varying the opening angle of the trap. For increasing angles, there is a sequence of three emergent states corresponding to partial, complete, and no trapping. A trapping `phase diagram' maps out the trap conditions under which the capture of self-propelled particles at a given density is rendered optimal.Comment: 5 pages, 4 figure

Slow-roll inflationary senario in the maximally extended background

During the inflationary epoch,geometry of the universe may be described by quasi-de Sitter space. On the other hand,maximally extended de Sitter metric in the comoving coordinates accords with a special FLRW model with positive spatial curvature,so in this article we focus on the positively curved inflationary paradigm.For this purpose,first we derive the power spectra of comoving curvature perturbation and primordial gravitational waves in a positively curved FLRW universe according to the slowly rolling inflationary senario. It can be shown that the curvature spectral index in this model automatically has a small negative running parameter which is compatible with observational measurements.Then,by taking into account the curvature factor,we investigate the relative amplitude of the scalar and tensor perturbations.It would be clarified that the tensor-scalar ratio for this model against the spatially flat one,depends on the waelength of the perturbative models directly.Comment: 21 pages,n o figure

Laser-Nucleus Reactions: Population of States far above Yrast and far from Stability

Nuclear reactions induced by a strong zeptosecond laser pulse are studied theoretically in the quasiadiabatic regime where the photon absorption rate is comparable to the nuclear equilibration rate. We find that multiple photon absorption leads to the formation of a compound nucleus in the so-far unexplored regime of excitation energies several hundred MeV above the yrast line. At these energies, further photon absorption is limited by neutron decay and/or induced nucleon emission. With a laser pulse of $\approx 50$ zs duration, proton-rich nuclei far off the line of stability are produced.Comment: 4 pages, 3 figures, small changes in v2 to match the published version, results unchange