567 research outputs found

    Penerapan Metode Dmaic dalam Peningkatan Acceptance Rate untuk Ukuran Panjang Produk Bushing

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    PT Argatama Multy Agung is one provider of metal cutting services using turret machine. The quality of metal cutting services offered are still questioned. The quality service intended is that the length accuracy of the outcome product meets the requirements of the requested length. The purpose of this study is to determine what factors lead to defects the goods length, as well as to provide the right solution that factors can be eliminated so that the number of defective products can be reduced. In this research authors implement Six Sigma methodology with an improved model of Define-Measure-Analyze-Improve-Control (DMAIC) to perform improvement in the services quality provided by PT Argatama Multy Agung. On the improvement phase Design Of Experiment (DOE) is used to find the machine configuration that can produce the best quality. From the research conducted, a significant increase of sigma is obtained

    Tap For Battle: Perancangan Casual Game pada Smartphone Android

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    Smartphones have become a necessity. Almost everyone uses a smartphone in a variety of activities. Both young and old are sure to utilize this technology, for a wide range of activities such as doing the work, doing school work or enjoying entertainment. The purpose of this research is to build a casual-action game with war theme. The game is built for Android smartphone that has multi touch screen capability. The research methods used in this research are data collection and analysis method including user analysis with questionnaire. Furthermore, IMSDD method is implemented for game design and development phase including system requirement analysis, system design, system implementation, finally system evaluation. In this research, we conclude that 83.9% participants enjoyed the game with touch-screen as the game control

    Analisis Komposisi Dan Struktur Vegetasi Terhadap Upaya Restorasi Kawasan Hutan Taman Nasional Gunung Gede Pangrango

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    Gunung Gede Pangrango National Park (GGPNP) Forest Area has many ecosystem/forest vegetation type. The research aim was to analysis vegetation structure and composition at GGPNP forest area in many forest vegetation type. Research conducted by through vegetation analysis activity by used squared strip method. The results show that form of horizontal stand structure of Natural Forest stand tend to come near form of J-inversed (negative eksponensial) letter spread and form of horizontal stand structure graph of Mixed Rasamala Forest, Mixed Puspa Forest, Damar Forest, and Pine Forest stand be under horizontal stand structure graph of Natural Forest stand. Natural Forest has species number and species diversity index of higher level type at all levels growth of vegetation if compared to others forest vegetation types. Natural Forest has species evenness index of higher level type only at tree growth level, but rather lower at seedling growth level, sapling growth level, and pole growth level if compared to others forest vegetation types. There were 15 vegetation species found at all of forest vegetation types which have potency as pioneer vegetation in restoration activity of GGPNP forest area

    An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

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    For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

    SEROPREVALENCE OF HIV, HBV, HCV, SYPHILIS AMONG DONORS OF BLOOD AT THE NATIONAL CENTER OF BLOOD TRANSFUSION ANTANANARIVO IN 2014

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    Introduction: Currently, routine screening for HIV, hepatitis B and C and syphilis is done in most blood banks in the world. Methods: We conducted a prospective descriptive study at the National Blood Transfusion Center (CNTS) Antananarivo for a period of 7 months from January to July 2014, which aims to assess the socio-clinical factors accompanying ineligibility of blood products and to determine the seroprevalence of HIV, hepatitis B, C and syphilis of the blood donors who have spent at CNTS HU JRA Antananarivo during this period. All donors who have abnormal results of microbiological examinations were included. The parameters used and studied were age, sex, marital status, blood and results microbiological examinations for HIV, hepatitis B, C, and syphilis. The prevalence of blood donors who presented a serological abnormality is 3.95% with a predominance of donors with hepatitis B (72.93%) followed by syphilis (18.29%) of the hepatitis C (6.95%) and HIV (1.80%) and a predominance of young people. Conclusion: At the CNTS Antananarivo, the HBV is the main definitive reason for exclusion of these donors. This high prevalence is a real public health problem for the country's health authorities. The search for maximum safety in blood transfusion through firstly a better selection of blood donors by implementing a policy of strong loyalty and other early diagnosis of major diseases transmissible by blood and likely to infect the recipient. KEYWORDS: Antananarivo; Blood donor; Microbiology; Seroprevalence

    Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

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    Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

    SEROPREVALENCE OF HIV, HBV, HCV, SYPHILIS AMONG DONORS OF BLOOD AT THE NATIONAL CENTER OF BLOOD TRANSFUSION ANTANANARIVO IN 2014

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    Introduction: Currently, routine screening for HIV, hepatitis B and C and syphilis is done in most blood banks in the world. Methods: We conducted a prospective descriptive study at the National Blood Transfusion Center (CNTS) Antananarivo for a period of 7 months from January to July 2014, which aims to assess the socio-clinical factors accompanying ineligibility of blood products and to determine the seroprevalence of HIV, hepatitis B, C and syphilis of the blood donors who have spent at CNTS HU JRA Antananarivo during this period. All donors who have abnormal results of microbiological examinations were included. The parameters used and studied were age, sex, marital status, blood and results microbiological examinations for HIV, hepatitis B, C, and syphilis. The prevalence of blood donors who presented a serological abnormality is 3.95% with a predominance of donors with hepatitis B (72.93%) followed by syphilis (18.29%) of the hepatitis C (6.95%) and HIV (1.80%) and a predominance of young people. Conclusion: At the CNTS Antananarivo, the HBV is the main definitive reason for exclusion of these donors. This high prevalence is a real public health problem for the country\u27s health authorities. The search for maximum safety in blood transfusion through firstly a better selection of blood donors by implementing a policy of strong loyalty and other early diagnosis of major diseases transmissible by blood and likely to infect the recipient. KEYWORDS: Antananarivo; Blood donor; Microbiology; Seroprevalence

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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