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Dynamic Behavior of Precast Concrete Beam-Column Sub-Assemblages with High Performance Connections Subjected to Sudden Column Removal Scenario
Unbonded posttensioned precast concrete (UPPC) structure has shown its excellent aseismic performance in laboratory tests and earthquake investigation. However, the progressive collapse behavior of UPPC subjected to column removal scenario is still unclear. To fill this knowledge gap, two 1/2 scaled UPPC beam-column sub-assemblages were tested under a penultimate column removal scenario. The dynamic test results indicated that UPPC sub-assemblages have desirable load redistribution capacity to mitigate progressive collapse. The failure modes of the sub-assemblages observed in dynamic test were quite similar to that in static counterparts
Robust variable selection in partially varying coefficient single-index model
By combining basis function approximations and smoothly clipped absolute deviation (SCAD) penalty, this paper proposes a robust variable selection procedure for a partially varying coefficient single-index model based on modal regression. The proposed procedure simultaneously selects significant variables in the parametric components and the nonparametric components. With appropriate selection of the tuning parameters, we establish the theoretical properties of our procedure, including consistency in variable selection and the oracle property in estimation. Furthermore, we also discuss the bandwidth selection and propose a modified expectation-maximization (EM)-type algorithm for the proposed estimation procedure. The finite sample properties of the proposed estimators are illustrated by some simulation examples.The research of Zhu is partially supported by National Natural Science Foundation of China (NNSFC) under Grants 71171075, 71221001 and 71031004. The research of Yu is supported by NNSFC under Grant 11261048
On the undetected error probability of a concatenated coding scheme for error control
Consider a concatenated coding scheme for error control on a binary symmetric channel, called the inner channel. The bit error rate (BER) of the channel is correspondingly called the inner BER, and is denoted by Epsilon (sub i). Two linear block codes, C(sub f) and C(sub b), are used. The inner code C(sub f), called the frame code, is an (n,k) systematic binary block code with minimum distance, d(sub f). The frame code is designed to correct + or fewer errors and simultaneously detect gamma (gamma +) or fewer errors, where + + gamma + 1 = to or d(sub f). The outer code C(sub b) is either an (n(sub b), K(sub b)) binary block with a n(sub b) = mk, or an (n(sub b), k(Sub b) maximum distance separable (MDS) code with symbols from GF(q), where q = 2(b) and the code length n(sub b) satisfies n(sub)(b) = mk. The integerim is the number of frames. The outercode is designed for error detection only
Pairing Correlations Near a Kondo-Destruction Quantum Critical Point
Motivated by the unconventional superconductivity observed in heavy-fermion
metals, we investigate pairing susceptibilities near a continuous quantum phase
transition of the Kondo-destruction type. We solve two-impurity Bose-Fermi
Anderson models with Ising and Heisenberg forms of the interimpurity exchange
interaction using continuous-time quantum Monte-Carlo and numerical
renormalization-group methods. Each model exhibits a Kondo-destruction quantum
critical point separating Kondo-screened and local-moment phases. For
antiferromagnetic interimpurity exchange interactions, singlet pairing is found
to be enhanced in the vicinity of the transition. Implications of this result
for heavy-fermion superconductivity are discussed.Comment: 5 pages, 5 figures + supplementary material 2 page, 2 figures:
Replaced with published versio
Role of noncoding RNA in vascular remodelling
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling. We highlight recent studies that demonstrate the involvement of ncRNAs in vein graft disease, in in-stent restenosis and in pulmonary arterial hypertension, with a particular focus on endothelial cell and vascular smooth muscle cell function. We also briefly discuss the emerging role of exosomal-derived ncRNAs and how this mechanism impacts on vascular function.
Recent findings: ncRNAs have been described as novel regulators in the pathophysiology of vascular injury, inflammation, and vessel wall remodelling. In particular, several studies have demonstrated that manipulation of miRNAs can reduce the burden of pathological vascular remodelling. Such studies have also shown that exosomal miRNA-mediated, cell-to-cell communication between endothelial cells and vascular smooth muscle cells is critical in the disease process. In addition to miRNAs, lncRNAs are emerging as regulators of vascular function in health and disease. Although lncRNAs are complex in both their sheer numbers and mechanisms of action, identifying their contribution to vascular disease is essential.
Summary: Given the important roles of ncRNAs in vascular injury and remodelling together will their capacity for cell-to-cell communication, manipulating ncRNA might provide novel therapeutic interventions
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