A two-layer dimension reduction and two-tier classification model for anomaly-based intrusion detection in IoT backbone networks

With increasing reliance on Internet of Things (IoT) devices and services, the capability to detect intrusions and malicious activities within IoT networks is critical for resilience of the network infrastructure. In this paper, we present a novel model for intrusion detection based on two-layer dimension reduction and two-tier classification module, designed to detect malicious activities such as User to Root (U2R) and Remote to Local (R2L) attacks. The proposed model is using component analysis and linear discriminate analysis of dimension reduction module to spate the high dimensional dataset to a lower one with lesser features. We then apply a two-tier classification module utilizing Naïve Bayes and Certainty Factor version of K-Nearest Neighbor to identify suspicious behaviors. The experiment results using NSL-KDD dataset shows that our model outperforms previous models designed to detect U2R and R2L attacks

Course-Skill Atlas: A National Longitudinal Dataset of Skills Taught in U.S. Higher Education Curricula

Higher education plays a critical role in driving an innovative economy by equipping students with knowledge and skills demanded by the workforce. While researchers and practitioners have developed data systems to track detailed occupational skills, such as those established by the U.S. Department of Labor (DOL), much less effort has been made to document which of these skills are being developed in higher education at a similar granularity. Here, we fill this gap by presenting Course-Skill Atlas – a longitudinal dataset of skills inferred from over three million course syllabi taught at nearly three thousand U.S. higher education institutions. To construct Course-Skill Atlas, we apply natural language processing to quantify the alignment between course syllabi and detailed workplace activities (DWAs) used by the DOL to describe occupations. We then aggregate these alignment scores to create skill profiles for institutions and academic majors. Our dataset offers a large-scale representation of college education’s role in preparing students for the labor market. Overall, Course-Skill Atlas can enable new research on the source of skills in the context of workforce development and provide actionable insights for shaping the future of higher education to meet evolving labor demands, especially in the face of new technologies

Development of an extrudable paste to build mycelium-bound composites

Mycelium-bound composites are promising materials for sustainable packaging, insulation, fashion, and architecture. However, moulding is the main fabrication process explored to date, strongly limiting the ability to design the complex shapes that could widen the range of applications. Extrusion is a facile and low energy-cost process that has not yet been explored for mycelium-bound composites with design freedom and structural properties. In this study, we combine cheap, easily and commonly available agricultural waste materials, bamboo microfibres, chitosan, and mycelium from Ganodermalucidum, to establish a composite mixture that is workable, extrudable and buildable. We study the impact of bamboo fibre size, chitosan concentration, pH and weight ratio of bamboo to chitosan to determine the optimum growth condition for the mycelium as well as high mechanical stiffness. The resulting materials have thus low energy costs, are sustainable and can be shaped easily. The developed composition is promising to further explore the use of mycelium-bound materials for structural applications using agricultural waste

Air injection into the stereotactic biopsy site in cerebral lesions; A feasibility study

We assessed the utility and safety of injecting a small amount of air into the stereotactic biopsy site. Specifically, we wanted to know whether it helps in visualizing the target on a post-op brain CT scan. In this clinical series, we chose our subjects by consecutive sampling, among candidates for frame-based stereotactic biopsy of a supratentorial cerebral lesion. By applying certain inclusion and exclusion criteria, twenty cases were biopsied by two surgeons in a four-month period. After obtaining the tissue sample, we injected 0.5-1 ml of filtered room air through the biopsy cannula. The immediate post-op CT scan was evaluated by two researchers for the presence and location of the air bubble. The subjects consisted of 12 male and 8 female patients, 10-76 years old. The histologic diagnosis rate was 100; 60 high - grade glioma, 20 low-grade glioma, 10 metastasis and one case of meningioma and brain abscess. The air bubble could be visualized in all cases within the lesion territory. In two cases (10) bubbles were also found in other locations. There was no neurologic or radiologic complications. Our findings substantiates the limited available literature in regard with safety and diagnostic usefulness of air bubbles. Further research is needed to verify and quantify the diagnostic impact and any complications attributable to this measure

A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies

Background The aim of this study is to describe the major evolutionary historical events among Leishmania, sandflies, and the associated animal reservoirs in detail, in accordance with the geographical evolution of the Earth, which has not been previously discussed on a large scale. Methodology and Principal Findings Leishmania and sandfly classification has always been a controversial matter, and the increasing number of species currently described further complicates this issue. Despite several hypotheses on the origin, evolution, and distribution of Leishmania and sandflies in the Old and New World, no consistent agreement exists regarding dissemination of the actors that play roles in leishmaniasis. For this purpose, we present here three centuries of research on sandflies and Leishmania descriptions, as well as a complete description of Leishmania and sandfly fossils and the emergence date of each Leishmania and sandfly group during different geographical periods, from 550 million years ago until now. We discuss critically the different approaches that were used for Leishmana and sandfly classification and their synonymies, proposing an updated classification for each species of Leishmania and sandfly. We update information on the current distribution and dispersion of different species of Leishmania (53), sandflies (more than 800 at genus or subgenus level), and animal reservoirs in each of the following geographical ecozones: Palearctic, Nearctic, Neotropic, Afrotropical, Oriental, Malagasy, and Australian. We propose an updated list of the potential and proven sandfly vectors for each Leishmania species in the Old and New World. Finally, we address a classical question about digenetic Leishmania evolution: which was the first host, a vertebrate or an invertebrate? Conclusions and Significance We propose an updated view of events that have played important roles in the geographical dispersion of sandflies, in relation to both the Leishmania species they transmit and the animal reservoirs of the parasites

Generalized Hyers-Ulam Stability of the Second-Order Linear Differential Equations

We prove the generalized Hyers-Ulam stability of the 2nd-order linear differential equation of the form +()+()=(), with condition that there exists a nonzero 1∶→ in 2() such that 1+()1+()1=0 and is an open interval. As a consequence of our main theorem, we prove the generalized Hyers-Ulam stability of several important well-known differential equations

Types of Human Papillomavirus (HPV) in Patients with ASCUS Pap Smear

Background and Objective: Human papillomavirus (HPV) is one of the common infectious and pathogenic agents, and some of its genotypes have the ability to cause malignant changes in the surface of mucous cells. By examining the prevalence of HPV in atypical squamous cells of undetermined significance (ASCUS) Pap smear according to the risk factors, we can make a more correct decision in choosing the evaluation method and directing the patient to report the ASCUS lesion. Therefore, the aim of this study is to investigate the types of human papillomavirus (HPV) in patients with ASCUS Pap smear. Methods: This cross-sectional study was conducted on 200 patients with ASCUS pap smear results and HPV test referred to the colposcopy clinic of Babol Ayatollah Rouhani Hospital during the last two years. Demographic information, history of obstetrics, history of OCP use, history of STD disease and high-risk behaviors, cervical treatments, HPV typing, Pap smear, colposcopy and cervical biopsy results were recorded and analyzed. Findings: The mean age of the patients was 33.83±8.09 years, and ASCUS pap smear showed 129 cases (64.5%) of high-risk papillomavirus, 16 cases (0.8%) of low-risk papillomavirus and 55 cases (27.5%) of both types. Cervical intraepithelial neoplasia grade 2 was in 18 cases (0.9%), cervical intraepithelial neoplasia grade 1 in 10 cases (0.5%) and cervical intraepithelial neoplasia grade 3 in 2 cases (0.1%). 17.1% of high-risk viruses caused cervical neoplasm. None of the low-risk viruses led to neoplasms and all of them were inflammatory. In both high-risk and low-risk cases, 14.5% neoplasm was seen. However, the relationship between the type of papillomavirus and the incidence of neoplasm was significant (p=0.058). Conclusion: Based on the results of this study, the ASCUS pap smear needs more detailed investigation such as colposcopy and cervical biopsy under the supervision of experts because it is associated with the high-risk HPV virus in many cases

The Effect of Vitamin D Deficiency on Pregnancy Outcomes

Background and Objective: Supplying vitamin D during pregnancy is necessary for fetal calcium homeostasis and bone growth and its mineralization, and its deficiency can lead to pregnancy complications. The present study was conducted to investigate the effect of vitamin D level on pregnancy outcomes in pregnant women. Methods: This cross-sectional study was conducted among 450 pregnant women referring to Ayatollah Rouhani Hospital in Babol. Mothers' information was collected using a questionnaire. Blood samples were collected from people to measure the serum 25 hydroxyvitamin D3 level by ELISA method using the EUROIMMUN kit. Patients were divided into two groups (vitamin D level 25) and were compared. Findings: 247 people (54.8%) had vitamin D level 25. People with lower vitamin D levels had significantly more gestational hypertension (p=0.03) and premature rupture of membranes (PROM) (p=0.04) compared to people with higher vitamin D levels. The variables of labor pain, diabetes, fetal growth restriction and prolonged pregnancy did not show significant differences in people with high and low levels of vitamin D. Pregnancy complications including pre-eclampsia, preterm delivery, placental abruption and fetal growth restriction did not show any significant difference in people with high and low levels of vitamin D. In the evaluation of neonatal outcomes, infant weight, infant gender, fifth minute Apgar, head circumference and admission to the neonatal intensive care unit, no significant differences were found. Conclusion: The results of the study showed that some pregnancy complications such as gestational hypertension and premature rupture of membranes (PROM) in pregnant women are related to vitamin D deficiency. Therefore, it is necessary to design plans to check the vitamin D level of mothers before pregnancy and correct it during pregnancy

Comparative performance of imagicides on Anopheles stephensi, main malaria vector in a malarious area, southern Iran

Abstract Background & objectives: Jiroft district has subtropical climate and prone to seasonal malaria transmission with annual parasite index (API) 4.2 per 1000 in 2006. Anopheles stephensi Liston is a dominant malaria vector. The monitoring of insecticide susceptibility and irritability was conducted using discriminative dose as described by WHO