Harnessing the senga institution of adolescent sex education for the control of HIV and STDs in rural Uganda.

Senga (father's sister) is a traditional channel of communication about sexual behaviour for adolescent females in rural Uganda. We evaluated a modification of this approach as an intervention for HIV and STDs in a pilot study in two intervention villages and one control village over 12 months. Eleven adult women and three adolescent girls were chosen and trained to become sengas. Adolescent girls were encouraged to visit the sengas for sexual health information. Adult sengas saw an average of 21 clients; adolescent sengas saw five. Adolescent girls made 45% of visits. The expected reasons for attending the sengas accounted for 51% of visits. Knowledge about HIV/AIDS, sexual communication skills, consistent condom use and family planning service use increased in the intervention group of girls over the study period and compared to control girls. Symptomatic STDs decreased in the intervention group. This intervention was readily accepted by the community; members of all ages and both sexes attended for a wider variety of reasons than anticipated. Adolescent girls in the intervention group showed improved knowledge, attitudes and practices related to HIV and STDs. This promising intervention warrants further testing in larger studies and other settings

Overview on sugar metabolism and its control in Lactococcus lactis - The input from in vivo NMR

The wide application of lactic acid bacteria in the production of fermented foods depends to a great extent on the unique features of sugar metabolism in these organisms. The relative metabolic simplicity and the availability of genetic tools made Lactococcus lactis the organism of choice to gain insight into metabolic and regulatory networks. In vivo nuclear magnetic resonance has proven a very useful technique to monitor non-invasively the dynamics of intracellular metabolite and co-factor pools following a glucose pulse. Examples of the application of this methodology to identify metabolic bottlenecks and regulatory sites are presented. The use of this information to direct metabolic engineering strategies is illustrated. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved

The Drosophila genome nexus: a population genomic resource of 623 Drosophila melanogaster genomes, including 197 from a single ancestral range population.

Hundreds of wild-derived Drosophila melanogaster genomes have been published, but rigorous comparisons across data sets are precluded by differences in alignment methodology. The most common approach to reference-based genome assembly is a single round of alignment followed by quality filtering and variant detection. We evaluated variations and extensions of this approach and settled on an assembly strategy that utilizes two alignment programs and incorporates both substitutions and short indels to construct an updated reference for a second round of mapping prior to final variant detection. Utilizing this approach, we reassembled published D. melanogaster population genomic data sets and added unpublished genomes from several sub-Saharan populations. Most notably, we present aligned data from phase 3 of the Drosophila Population Genomics Project (DPGP3), which provides 197 genomes from a single ancestral range population of D. melanogaster (from Zambia). The large sample size, high genetic diversity, and potentially simpler demographic history of the DPGP3 sample will make this a highly valuable resource for fundamental population genetic research. The complete set of assemblies described here, termed the Drosophila Genome Nexus, presently comprises 623 consistently aligned genomes and is publicly available in multiple formats with supporting documentation and bioinformatic tools. This resource will greatly facilitate population genomic analysis in this model species by reducing the methodological differences between data sets

Microminiaturized, biopotential conditioning system (MBCS)

Multichannel, medical monitoring system allows almost complete freedom of movement for subject during monitoring periods. System comprises monitoring unit (biobelt), transmission line, and data acquisition unit. Belt, made of polybenzimidizole fabric, is wrapped around individual's waist and held in place by overlapping sections of Velcro closure material

VIS: the visible imager for Euclid

Euclid-VIS is a large format visible imager for the ESA Euclid space mission in their Cosmic Vision program, scheduled for launch in 2019. Together with the near infrared imaging within the NISP instrument it forms the basis of the weak lensing measurements of Euclid. VIS will image in a single r+i+z band from 550-900 nm over a field of view of ~0.5 deg2. By combining 4 exposures with a total of 2240 sec, VIS will reach to V=24.5 (10{\sigma}) for sources with extent ~0.3 arcsec. The image sampling is 0.1 arcsec. VIS will provide deep imaging with a tightly controlled and stable point spread function (PSF) over a wide survey area of 15000 deg2 to measure the cosmic shear from nearly 1.5 billion galaxies to high levels of accuracy, from which the cosmological parameters will be measured. In addition, VIS will also provide a legacy imaging dataset with an unprecedented combination of spatial resolution, depth and area covering most of the extra-Galactic sky. Here we will present the results of the study carried out by the Euclid Consortium during the Euclid Definition phase.Comment: 10 pages, 6 figure

Being Invited: Ethics in Participant-Researcher Relationships

This article examines the act of ‘being invited’ by research participants to explore asymmetrical power relations and research ethics in ethnographies along migration trajectories. It uses the lens of money in research relationships to explore agency and the reversal of power through hospitality and gift-giving. I examine invitations in the research process as (a) a way for researchers to gain access to their research subject and (b) a way for interlocutors to renegotiate and invert the research process. Drawing on a 9-month multi-sited ethnography along the trajectory of undocumented migration from Afghanistan to Germany, I relied on continuous invitations to revisit interlocutors. First, I argue that invitations are the necessary entry point into research sites, but are often excluded from considerations of research ethics. Second, an examination of ‘being invited’ as a concept shows that interlocutors shape the research process and exercise agency through a moral economy of research relations.Introduction Ethics, money, and hospitality in asymmetric research relationships ‘Being invited’: Entering ethnography ‘Being the host’: Participants’ agency and relocation of power dynamics Conclusion Reference

Manual therapy, physical therapy, or continued care by a general practitioner for patients with neck pain - A randomized, controlled trial

BACKGROUND: Neck pain is a common problem, but the effectiveness of frequently applied conservative therapies has never been directly compared. OBJECTIVE: To determine the effectiveness of manual therapy, physical therapy, and continued care by a general practitioner. DESIGN: Randomized, controlled trial. SETTING: Outpatient care setting in the Netherlands. PATIENTS: 183 patients, 18 to 70 years of age, who had had nonspecific neck pain for at least 2 weeks. INTERVENTION: 6 weeks of manual therapy (specific mobilization techniques) once per week, physical therapy (exercise therapy) twice per week, or continued care by a general practitioner (analgesics, counseling, and education). MEASUREMENTS: Treatment was considered successful if the patient reported being "completely recovered" or "much improved" on an ordinal six-point scale. Physical dysfunction, pain intensity, and disability were also measured. RESULTS: At 7 weeks, the success rates were 68.3% for manual therapy, 50.8% for physical therapy, and 35.9% for continued care. Statistically significant differences in pain intensity with manual therapy compared with continued care or physical therapy ranged from 0.9 to 1.5 on a scale of 0 to 10. Disability scores also favored manual therapy, but the differences among groups were small. Manual therapy scored consistently better than the other two interventions on most outcome measures. Physical therapy scored better than continued care on some outcome measures, but the differences were not statistically significant. CONCLUSION: In daily practice, manual therapy is a favorable treatment option for patients with neck pain compared with physical therapy or continued care by a general practitioner. (aut. ref.

Immobility Beyond Borders: Differential Inclusion and the Impact of the COVID-19 Border Closures

This article discusses differential inclusion as it relates to mobility in Europe through migrants’ experiences of the closure of the European Union (EU) Schengen borders during the COVID-19 pandemic. Based on 36 comparative online interviews with three groups of migrants – Erasmus students, asylum seekers and seasonal workers – the article empirically investigates how differential inclusion is reflected in migrants’ perceptions of border closures and the impact of border closures on international mobility. Drawing on the concept of differential inclusion, I examine the divergent border mobilities in a moment of crisis. In the interviews, migrants’ reflections on borders are informed either by their own perception of borders, their surprise at the lack of awareness of borders for other migrants, or the realisation that closed borders are crossed for capitalist economic demands under high health risks. Taking this as its basis, the article makes two arguments. First, that preexisting differential inclusion exacerbated during border closures in a global health emergency. Second, that borders are not concrete but flexible in (im)mobilising people according to capitalist economic demands. In this way, the article contributes to an understanding of the process of rebordering that took place during COVID-19 and in which borders remained spaces of differentiation.Introduction Embodied borders, differential inclusion and COVID-19 border closures Data and method Background: Differing (im)mobilities in the EU during the COVID-19 border closures Discussion: Border perspectives and differential inclusion Conlcusion Reference

Information-theoretic principle entails orthomodularity of a lattice

Quantum logical axiomatic systems for quantum theory usually include a postulate that a lattice under consideration is orthomodular. We propose a derivation of orthomodularity from an information-theoretic axiom. This provides conceptual clarity and removes a long-standing puzzle about the meaning of orthomodularity.Comment: Version prior to published, with slight modification

Spin-Glass State in CuGa2O4\rm CuGa_2O_4

Magnetic susceptibility, magnetization, specific heat and positive muon spin relaxation (\musr) measurements have been used to characterize the magnetic ground-state of the spinel compound $\rm CuGa_2O_4$. We observe a spin-glass transition of the S=1/2 $\rm Cu^{2+}$ spins below $\rm T_f=2.5K$ characterized by a cusp in the susceptibility curve which suppressed when a magnetic field is applied. We show that the magnetization of $\rm CuGa_2O_4$ depends on the magnetic histo Well below $\rm T_f$, the muon signal resembles the dynamical Kubo-Toyabe expression reflecting that the spin freezing process in $\rm CuGa_2O_4$ results Gaussian distribution of the magnetic moments. By means of Monte-Carlo simulati we obtain the relevant exchange integrals between the $\rm Cu^{2+}$ spins in this compound.Comment: 6 pages, 16 figure