14,391 research outputs found

    New computer system simplifies programming of mathematical equations

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    Automatic Mathematical Translator /AMSTRAN/ permits scientists or engineers to enter mathematical equations in their natural mathematical format and to obtain an immediate graphical display of the solution. This automatic-programming, on-line, multiterminal computer system allows experienced programmers to solve nonroutine problems

    Cell seeding chamber for bone graft substitutes

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    There is an increasing demand for bone graft substitutes that are used as osteoconductive scaffolds in the treatment of bone defects and fractures. Achieving optimal bone regeneration requires initial cell seeding of the scaffolds prior to implantation. The cell seeding chamber is a closed assembly. It works like a sandglass. The position of the scaffold is between two reservoirs containing the fluid (e. g. blood). The fluid at the upper reservoir flows through the scaffold driven by gravity. Fluid is collected at the lower reservoir. If the upper reservoir is empty the whole assembly turned and the process starts again. A new compact cell seeding chamber for initial cell seeding has been developed that can be used in the operating theater

    Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles

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    Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal antibody against β‐MSP were used for immunocytochemical detection of the respective antigens in different organs from different species. SG immunoreactivity was detected in the epithelium of the pubertal and adult human and in monkey seminal vesicle, ampulla of the vas deferens, and ejaculatory duct. PAP, β‐MSP, and PSA immunoreactivities were detected in the pubertal and adult human prostate and the cranial and caudal monkey prostate. With the exception of a weak PSA immunoreactivity in the proximal portions of the ejaculatory duct, none of the latter antisera reacted with seminal vesicle, ampullary, and ejaculatory duct epithelium. Among the non‐primate species studied (dog, bull, rat, guinea pig) only the canine prostatic epithelium displayed a definite immunoreactivity with the PAP antibody and a moderate reaction with the PSA antibody. No immunoreaction was seen in bull and rat seminal vesicle and canine ampulla of the vas deferens with the SG antibody. The same was true for the (ventral) prostate of rat, bull, and dog for β‐MSP. The epithelium of the rat dorsal prostate showed a slight cross‐reactivity with the monoclonal antibody against β‐MSP and one polyclonal antibody against PSA. The findings indicate a rather strict species‐dependent expression of human seminal proteins which show some similarities in primates, but only marginal relationship to species with different physiology of seminal fluid

    Behavior of heuristics and state space structure near SAT/UNSAT transition

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    We study the behavior of ASAT, a heuristic for solving satisfiability problems by stochastic local search near the SAT/UNSAT transition. The heuristic is focused, i.e. only variables in unsatisfied clauses are updated in each step, and is significantly simpler, while similar to, walksat or Focused Metropolis Search. We show that ASAT solves instances as large as one million variables in linear time, on average, up to 4.21 clauses per variable for random 3SAT. For K higher than 3, ASAT appears to solve instances at the ``FRSB threshold'' in linear time, up to K=7.Comment: 12 pages, 6 figures, longer version available as MSc thesis of first author at http://biophys.physics.kth.se/docs/ardelius_thesis.pd

    Microlensing events from the 11-year observations of the Wendelstein Calar Alto Pixellensing Project

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    We present the results of the decade-long M31 observation from the Wendelstein Calar Alto Pixellensing Project (WeCAPP). WeCAPP has monitored M31 from 1997 till 2008 in both R- and I-filters, thus provides the longest baseline of all M31 microlensing surveys. The data are analyzed with the difference imaging analysis, which is most suitable to study variability in crowded stellar fields. We extracted light curves based on each pixel, and devised selection criteria that are optimized to identify microlensing events. This leads to 10 new events, and sums up to a total of 12 microlensing events from WeCAPP, for which we derive their timescales, flux excesses, and colors from their light curves. The color of the lensed stars fall between (R-I) = 0.56 to 1.36, with a median of 1.0 mag, in agreement with our expectation that the sources are most likely bright, red stars at post main-sequence stage. The event FWHM timescales range from 0.5 to 14 days, with a median of 3 days, in good agreement with predictions based on the model of Riffeser et al. (2006).Comment: 44 pages, 16 figures, 5 tables. ApJ accepte

    The Wendelstein Calar Alto Pixellensing Project (WeCAPP): the M31 Nova catalogue

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    We present light curves from the novae detected in the long-term, M31 monitoring WeCAPP project. The goal of WeCAPP is to constrain the compact dark matter fraction of the M31 halo with microlensing observations. As a by product we have detected 91 novae benefiting from the high cadence and highly sensitive difference imaging technique required for pixellensing. We thus can now present the largest CCD and optical filters based nova light curve sample up-to-date towards M31. We also obtained thorough coverage of the light curve before and after the eruption thanks to the long-term monitoring. We apply the nova taxonomy proposed by Strope et al. (2010) to our nova candidates and found 29 S-class novae, 10 C-class novae, 2 O-class novae and 1 J-class nova. We have investigated the universal decline law advocated by Hachichu and Kato (2006) on the S-class novae. In addition, we correlated our catalogue with the literature and found 4 potential recurrent novae. Part of our catalogue has been used to search for optical counter-parts of the super soft X-ray sources detected in M31 (Pietsch et al. 2005). Optical surveys like WeCAPP, and coordinated with multi-wavelength observation, will continue to shed light on the underlying physical mechanism of novae in the future.Comment: 15 pages, 15 figures, 7 tables, A&A accepted for publication. The appendix is stored in the Data Conservanc

    The GALATEA Test-Facility for High Purity Germanium Detectors

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    GALATEA is a test facility designed to investigate bulk and surface effects in high purity germanium detectors. A vacuum tank houses an infrared screened volume with a cooled detector inside. A system of three stages allows an almost complete scan of the detector. The main feature of GALATEA is that there is no material between source and detector. This allows the usage of alpha and beta sources as well as of a laser beam to study surface effects. A 19-fold segmented true-coaxial germanium detector was used for commissioning

    Hubble Space Telescope weak lensing study of the z=0.83 cluster MS 1054-03

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    We have measured the weak gravitational lensing signal of MS 1054-03, a rich and X-ray luminous cluster of galaxies at a redshift of z=0.83, using a two-colour mosaic of deep WFPC2 images. The small corrections for the size of the PSF and the high number density of background galaxies obtained in these observations result in an accurate and well calibrated measurement of the lensing induced distortion. The strength of the lensing signal depends on the redshift distribution of the background galaxies. We used photometric redshift distributions from the Northern and Southern Hubble Deep Fields to relate the lensing signal to the mass. The predicted variations of the signal as a function of apparent source magnitude and colour agrees well with the observed lensing signal. We determine a mass of (1.2+-0.2)x10^15 Msun within an aperture of radius 1 Mpc. Under the assumption of an isothermal mass distribution, the corresponding velocity dispersion is 1311^{+83}_{-89} km/s. For the mass-to-light ratio we find 269+-37 Msun/Lsun. The errors in the mass and mass-to-light ratio include the contribution from the random intrinsic ellipticities of the source galaxies, but not the (systematic) error due to the uncertainty in the redshift distribution. However, the estimates for the mass and mass-to-light ratio of MS 1054-03 agree well with other estimators, suggesting that the mass calibration works well. The reconstruction of the projected mass surface density shows a complex mass distribution, consistent with the light distribution. The results indicate that MS 1054-03 is a young system. The timescale for relaxation is estimated to be at least 1 Gyr. Averaging the tangential shear around the cluster galaxies, we find that the velocity dispersion of an Lstar galaxy is 203+-33 km/s.Comment: 21 pages, Latex, with 27 figures (3 figures bitmapped), ApJ, in press. Version (with non-bitmapped figures) available at http://www.astro.rug.nl/~hoekstra/papers.htm
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