Tuberculin skin test results in HIV-infected patients in India: implications for latent tuberculosis treatment

OBJECTIVE: To evaluate the utility of the tuberculin skin test (TST) in detecting latent and active tuberculosis (TB) among human immunodeficiency virus (HIV) infected patients in South India. DESIGN: TSTs and CD4 counts were collected from 631 HIV-infected individuals without active TB and 209 antiretroviral and anti-tuberculosis treatment-naïve HIVinfected patients with TB. We calculated the proportion of TST-positive individuals, as well as the sensitivity, specificity, positive predictive value (PPV) and negative predictive value of TST in the diagnosis of TB. RESULTS: Among subjects without active TB, 28% with a CD4 count �100 cells/�l vs. 43% of the total cohort had a TST �5 mm (P � 0.14), while the proportions with induration �10 mm were 14% vs. 36%, respectively (P � 0.01). Among those with active TB, using a 5 mm cut-off, the sensitivity was 42% for those with CD4 counts �200 cells/�l compared to 70% for those with CD4 counts �200 cells/�l (P � 0.001). The PPV for detecting active TB was 29%. CONCLUSIONS: TST is a poor predictor of both latent and active TB in HIV-infected individuals in TB endemic countries. Programmes offering treatment for latent TB should consider including all HIV-positive patients regardless of TST status, or use other indicators, such as CD4 count

Vortex behavior near a spin vacancy in 2D XY-magnets

The dynamical behavior of anisotropic two dimensional Heisenberg models is still a matter of controversy. The existence of a central peak at all temperatures and a rich structure of magnon peaks are not yet understood. It seems that the central peaks are related, in some way, to structures like vortices. In order to contribute to the discussion of the dynamical behavior of the model we use Monte Carlo and spin dynamics simulations as well analytical calculations to study the behavior of vortices in the presence of nonmagnetic impurities. Our simulations show that vortices are attracted and trapped by the impurities. Using this result we show that if we suppose that vortices are not very much disturbed by the presence of the impurities, then they work as an attractive potential to the vortices explaining the observed behavior in our simulations.Comment: 4 pages, 6 figure

Monte Carlo study of the critical temperature for the planar rotator model with nonmagnetic impurities

We performed Monte Carlo simulations to calculate the Berezinskii-Kosterlitz-Thouless (BKT) temperature $T_{BKT}$ for the two-dimensional planar rotator model in the presence of nonmagnetic impurity concentration $(\rho)$. As expected, our calculation shows that the BKT temperature decreases as the spin vacancies increase. There is a critical dilution $\rho_c \approx 0.3$ at which $T_{BKT} =0$. The effective interaction between a vortex-antivortex pair and a static nonmagnetic impurity is studied analytically. A simple phenomenological argument based on the pair-impurity interaction is proposed to justify the simulations.Comment: 5 pages, 5 figures, Revetex fil

Role of Light Vector Mesons in the Heavy Particle Chiral Lagrangian

We give the general framework for adding "light" vector particles to the heavy hadron effective chiral Lagrangian. This has strong motivations both from the phenomenological and aesthetic standpoints. An application to the already observed D \rightarrow \overbar{K^*} weak transition amplitude is discussed.Comment: 19 pages, LaTeX documen

Baryons with Two Heavy Quarks as Solitons

Using the chiral soliton model and heavy quark symmetry we study baryons containing two heavy quarks. If there exists a stable (under strong interactions) meson consisting of two heavy quarks and two light ones, then we find that there always exists a state of this meson bound to a chiral soliton and to a chiral anti-soliton, corresponding to a two heavy quark baryon and a baryon containing two heavy anti-quarks and five light quarks, or a ``heptaquark".Comment: 7 pages and 2 postscript figures appended, LaTex, UCI-TR 94-3

Heavy Quark Solitons: Strangeness and Symmetry Breaking

We discuss the generalization of the Callan-Klebanov model to the case of heavy quark baryons. The light flavor group is considered to be $SU(3)$ and the limit of heavy spin symmetry is taken. The presence of the Wess-Zumino-Witten term permits the neat development of a picture , at the collective level, of a light diquark bound to a ``heavy" quark with decoupled spin degree of freedom. The consequences of $SU(3)$ symmetry breaking are discussed in detail. We point out that the $SU(3)$ mass splittings of the heavy baryons essentially measure the ``low energy" physics once more and that the comparison with experiment is satisfactory.Comment: 17 pages, RevTEX. Minor typos corrected and new references adde

Morphology of supported polymer electrolyte ultra-thin films: a numerical study

Morphology of polymer electrolytes membranes (PEM), e.g., Nafion, inside PEM fuel cell catalyst layers has significant impact on the electrochemical activity and transport phenomena that determine cell performance. In those regions, Nafion can be found as an ultra-thin film, coating the catalyst and the catalyst support surfaces. The impact of the hydrophilic/hydrophobic character of these surfaces on the structural formation of the films has not been sufficiently explored yet. Here, we report about Molecular Dynamics simulation investigation of the substrate effects on the ionomer ultra-thin film morphology at different hydration levels. We use a mean-field-like model we introduced in previous publications for the interaction of the hydrated Nafion ionomer with a substrate, characterized by a tunable degree of hydrophilicity. We show that the affinity of the substrate with water plays a crucial role in the molecular rearrangement of the ionomer film, resulting in completely different morphologies. Detailed structural description in different regions of the film shows evidences of strongly heterogeneous behavior. A qualitative discussion of the implications of our observations on the PEMFC catalyst layer performance is finally proposed

Heavy Quark Solitons

We investigate the heavy baryons which arise as solitonic excitations in a ``heavy meson" chiral Lagrangian which includes the light vector particles. It is found that the effect of the light vectors may be substantial. We also present a simple derivation which clearly shows the connection to the Callan-Klebanov approach.Comment: 13 pages; LaTex; SU-4240-532; UR 1306/ER-40685-755 (Minor typos corrected

Effective Hadron Dynamics: From Meson Masses to the Proton Spin Puzzle

We construct a three flavor chiral Lagrangian of pseudoscalars and vectors with special emphasis on the symmetry breaking terms. Comparing tree level two and three point functions with experiment allows us to first, fix the parameters of the model (including the light quark mass ratios) and second, to predict $m(K^{*+})-m(K^{*\circ}),\, \Gamma(K^*\rightarrow K\pi)$ and $\Gamma(\phi\rightarrow K {\overline K})$. The last mentioned quantities come out reasonably well, in contrast to an ``ordinary" $SU(3)$ treatment. For this purpose we need ``second order" symmetry breakers involving the vector fields analogous to those needed for the chiral perturbation theory program with only pseudoscalars. An improved description of the $\eta-\eta^\prime$ system is also given. We then use the soliton sector of this improved chiral Lagrangian to investigate some aspects of baryon physics which are especially sensitive to symmetry breaking. For this purpose a fairly elaborate ``cranking" techinque is employed in connection with the collective Hamiltonian. In addition to the ``strong" baryon mass spectrum a careful investigation is made of the non-electromagnetic part of the neutron-proton mass difference. This work is needed to improve our previous estimates concerning the two component approach to the ``proton spin" puzzle. We find that both the ``matter" and ``glue" contributions are small but they do tend to cancel each other.Comment: 33 pages, LaTe

Overview of marine fisheries in India during 2007

Fisheries sector in India plays an important role in the country’s economy and it supports the livelihood of millions of people. India is having 8,129 km of coastal length with 2.02 million sq. km of Exclusive Economic Zone (upto 200 m depth) and 0.452 million sq. km of continental shelf area