The Marriage of Heaven and Hell? Philip Pullman, C.S. Lewis, and the Fantasy Tradition

Closely scrutinizes Pullman’s frequent denials of his quite obvious debt to C.S. Lewis, finding the hidden nuances in Pullman’s statements by separating out his responses to Lewis as a reader, author, and critic. The inescapable conclusion is that not only is Pullman writing classic fantasy, he is in close agreement with Lewis on many points as a reader and critic

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

O uso de textos polêmicos em sala de aula: formação e prática docente

O objetivo deste texto é duplo. Primeiro, analisa como Discursos, formas socialmente aceitas de falar/ouvir e escrever/ler sobre sujeitos em grupos sociais específicos (Gee, 2008), podem influenciar o uso ou a censura a textos polêmicos por docentes em sala de aula. Discute o que as pesquisas têm revelado sobre docentes utilizando em suas aulas o tema da diversidade. A partir de exemplo de livro de literatura sobre a temática do racismo, traz sugestões para que os professores possam conduzir discussões que respeitem a diversidade cultural de seus alunos e propiciem a formação de opiniões críticas, fazendo assim do professor da educação básica um sujeito responsivo

<b>My Own Invention</b> - Ten Years of Excellence in Poetry for Children

Daniel Hade surveys 10 years of the Lee Bennett Hopkins Poetry Award which aims to recognize annually the most outstanding new book of poetry for young people and generally to promote the reading enjoyment of poetry for children

<b>Illuminating Texts</b>: - A Short Primer on Children's Books in the Global Economy

Eight publishing corporations produced over 84% of the books reviewed in The Horn Book Magazine in 2000 and over 75% of the books that received a starred review in The School Library Journal in 2000. These corporations' interests in children's books have little to do with bringing compelling stories to children. Rather, their interests run to "branding," "licensing," "vertical integration," "meaning brokering," and "synergy," because these are the paths to greater sales and profits. When we unpack what these words and phrases mean, what we find is chilling

Inside The Picture, Outside The Frame: Semiotics And The Reading Of Wordless Picture Books

The publishing world has witnessed a proliferation of word less children’s books during th e past 40 years. Books in this genre offer young readers invitat ionsto transact with a whole system of images as th ey navigate these texts. Using asemiotic framework, this study focuses on three children’s readings of word less picture books and explores the ways in which they assign meaning to a variety of visual signs and cues. The data indicate that the children make sens e of wordlesspicture books by using sense-making processes similar to those used in the reading of print-based texts. Specifically, they construct mean ing through the use of priorknowledge and experiences, attention to inter textual cues, multiple perspectivetaking, reliance upon story langu age and rituals, and the implementation ofactive, playful behaviors as part of the reading process. © 2000 by the Association for Childhood Education International