264 research outputs found

    Review of Person Re-identification Techniques

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    Person re-identification across different surveillance cameras with disjoint fields of view has become one of the most interesting and challenging subjects in the area of intelligent video surveillance. Although several methods have been developed and proposed, certain limitations and unresolved issues remain. In all of the existing re-identification approaches, feature vectors are extracted from segmented still images or video frames. Different similarity or dissimilarity measures have been applied to these vectors. Some methods have used simple constant metrics, whereas others have utilised models to obtain optimised metrics. Some have created models based on local colour or texture information, and others have built models based on the gait of people. In general, the main objective of all these approaches is to achieve a higher-accuracy rate and lowercomputational costs. This study summarises several developments in recent literature and discusses the various available methods used in person re-identification. Specifically, their advantages and disadvantages are mentioned and compared.Comment: Published 201

    Actin polymerization controls the activation of multidrug efflux at fertilization by translocation and fine-scale positioning of ABCB1 on microvilli.

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    © The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology of the Cell 23 (2012): 3663-3672, doi:10.1091/mbc.E12-06-0438.Fertilization changes the structure and function of the cell surface. In sea urchins, these changes include polymerization of cortical actin and a coincident, switch-like increase in the activity of the multidrug efflux transporter ABCB1a. However, it is not clear how cortical reorganization leads to changes in membrane transport physiology. In this study, we used three-dimensional superresolution fluorescence microscopy to resolve the fine-scale movements of the transporter along polymerizing actin filaments, and we show that efflux activity is established after ABCB1a translocates to the tips of the microvilli. Inhibition of actin poly­merization or bundle formation prevents tip localization, resulting in the patching of ABCB1a at the cell surface and decreased efflux activity. In contrast, enhanced actin polymerization promotes tip localization. Finally, interference with Rab11, a regulator of apical recycling, inhibits activation of efflux activity in embryos. Together our results show that actin-mediated, short-range traffic and positioning of transporters at the cell surface regulates multidrug efflux activity and highlight the multifaceted roles of microvilli in the spatial distribution of membrane proteins.Funding was provided by the National Institute of Child Health and Human Development (058070), the National Center for Research Resources (P30-NS047101), the Krinsk Research Advancement Initiative to A.H., a Scripps Postdoctoral Scholar Fellowship to K.W., and NICHD award 062178 to A.M.R

    Pattern of thyroid diseases in central Sudan: Nuclear medicine perspective

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    Thyroid scintigraphy using Tc-99m pertechnetate is a frequently performed procedure in routine nuclear medicine practice in addition to thyroid hormonal assay by radioimmunoassay (RIA). There is no clear description of thyroid diseases pattern in Sudan using nuclear medicine as a diagnostic tool. The aim of this retrospective study is to determine the pattern of thyroid diseases using the nuclear medicine facilities in our institute during a period (2001-2003). Methods: All patients referred to the department of nuclear medicine for thyroid scan from January 2001 to December 2003 were included in this study and the thyroid function test when available. Data were analyzed by SPSS software. Results: A total of 2070 patients were referred to the department and only 1605 (77.5%) have thyroid function test results available for scan reporting. Female to male ratio is 9:1. The mean age is 34 ±13.36 (1-86 years old). The most common pattern is simple multinodular goiter 784 (37.8%) and the second is solitary thyroid nodule 506 (24.4%), followed by simple diffuse goiter 415 (20%). From a total of 1605 thyroid function test results, 1377 patients (85.8%) were euthyroid, 168 (10.5%) were having hyperthyroidism while only 60 (3.7%) were having hypothyroidism. Conclusion: The vast majority of patients in this study were young females with simple goiter and normal radionuclide uptake. No more information gained particularly when the patient is known clinically and biochemically to have a simple goiter. A solitary cold nodule is also common.Keywords: Thyroid scan, goiter, cold nodule, iodine deficiency, thyroid disease

    Biopiracy <i>versus </i>one-world medicine – from colonial relicts to global collaborative concepts

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    Background: Practices of biopiracy to use genetic resources and indigenous knowledge by Western companies without benefit-sharing of those, who generated the traditional knowledge, can be understood as form of neocolonialism.Hypothesis: : The One-World Medicine concept attempts to merge the best of traditional medicine from developing countries and conventional Western medicine for the sake of patients around the globe.Study design: Based on literature searches in several databases, a concept paper has been written. Legislative initiatives of the United Nations culminated in the Nagoya protocol aim to protect traditional knowledge and regulate benefit-sharing with indigenous communities. The European community adopted the Nagoya protocol, and the corresponding regulations will be implemented into national legislation among the member states. Despite pleasing progress, infrastructural problems of the health care systems in developing countries still remain. Current approaches to secure primary health care offer only fragmentary solutions at best. Conventional medicine from industrialized countries cannot be afforded by the impoverished population in the Third World. Confronted with exploding costs, even health systems in Western countries are endangered to burst. Complementary and alternative medicine (CAM) is popular among the general public in industrialized countries, although the efficacy is not sufficiently proven according to the standards of evidence-based medicine. CAM is often available without prescription as over-the-counter products with non-calculated risks concerning erroneous self-medication and safety/toxicity issues. The concept of integrative medicine attempts to combine holistic CAM approaches with evidence-based principles of conventional medicine.Conclusion: To realize the concept of One-World Medicine, a number of standards have to be set to assure safety, efficacy and applicability of traditional medicine, e.g. sustainable production and quality control of herbal products, performance of placebo-controlled, double-blind, randomized clinical trials, phytovigilance, as well as education of health professionals and patients

    Morphology selection of nanoparticle dispersions by polymer media

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    A systematic theory of ultrathin polymer films as organizing media to achieve 2D nanoparticle arrangements was developed. The key physical variables to achieve nanoparticle dispersions and control morphology were determined.open727

    Image subset communication for resource-constrained applications in wireless sensor networks

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    Exploitation of TerraSAR-X Data for Land use/Land Cover Analysis Using Object-Oriented Classification Approach in the African Sahel Area, Sudan.

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    Recently, object-oriented classification techniques based on image segmentation approaches are being studied using high-resolution satellite images to extract various thematic information. In this study different types of land use/land cover (LULC) types were analysed by employing object-oriented classification approach to dual TerraSAR-X images (HH and HV polarisation) at African Sahel. For that purpose, multi-resolution segmentation (MRS) of the Definiens software was used for creating the image objects. Using the feature space optimisation (FSO) tool the attributes of the TerraSAR-X image were optimised in order to obtain the best separability among classes for the LULC mapping. The backscattering coefficients (BSC) for some classes were observed to be different for HH and HV polarisations. The best separation distance of the tested spectral, shape and textural features showed different variations among the discriminated LULC classes. An overall accuracy of 84 % with a kappa value 0.82 was resulted from the classification scheme, while accuracy differences among the classes were kept minimal. Finally, the results highlighted the importance of a combine use of TerraSAR-X data and object-oriented classification approaches as a useful source of information and technique for LULC analysis in the African Sahel drylands

    Magnetization study of Ni/Ag multilayers

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    The magnetic properties of Ni/Ag multilayers, prepared by evaporation in ultrahigh vacuum under controlled conditions, have been systematically studied by magnetic measurements. A spin-wave theory has been used to explain the temperature dependence of the magnetization and the approximate values for the bulk exchange interaction Jb and surface exchange interaction JS for various Ni layer thicknesses have been obtained.The magnetic properties of Ni/Ag multilayers, prepared by evaporation in ultrahigh vacuum under controlled conditions, have been systematically studied by magnetic measurements. A spin-wave theory has been used to explain the temperature dependence of the magnetization and the approximate values for the bulk exchange interaction Jb and surface exchange interaction JS for various Ni layer thicknesses have been obtained
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