Large scale correlations of quasar polarisation vectors: Hints of extreme scale structures?

A survey measuring quasar polarization vectors has been started in two regions towards the North and South Galactic Poles. Here, We review the discovery of significant correlations of orientations of polarization vectors over huge angular distances. We report new results including a larger sample of the quasars confirming the existence of coherent orientations at redshifts z>1.Comment: Proc. of Astronomical Polarimetry - Current Status and Future Directions March 15-19, 2004. Waikoloa Beach Marriott, Hawaii. 5 pages, 3 figure

Building patterns by traveling vortices and dipoles in periodic dissipative media

We analyze pattern-formation scenarios in the two-dimensional (2D) complex Ginzburg-Landau (CGL) equation with the cubic-quintic (CQ) nonlinearity and a cellular potential. The equation models laser cavities with built-in gratings, which are used to stabilize 2D patterns. The pattern-building process is initiated by kicking a localized compound mode, in the form of a dipole, quadrupole, or vortex which is composed of four local peaks. The hopping motion of the kicked mode through the cellular structure leads to the generation of various extended patterns pinned by the structure. In the ring-shaped system, the persisting freely moving dipole hits the stationary pattern from the opposite side, giving rise to several dynamical regimes, with the pinned multi-soliton chain playing the role of the Newton's cradle (NC)

A strict lower-limit EBL: Applications on gamma-ray absorption

A strict lower limit flux for the extragalactic background light from ultraviolet to the far-infrared photon energies is presented. The spectral energy distribution is derived using an established EBL model based on galaxy formation. The model parameters are chosen to fit the lower limit data from number count observations in particular recent results by the SPITZER infrared space telescope. A lower limit EBL model is needed to calculate guaranteed absorption due to pair production in extragalactic gamma-ray sources as in TeV blazars.Comment: Comments: 4 pages, 2 figures, submitted to proceedings of "4th Heidelberg International Symposium on High Energy Gamma-Ray Astronomy 2008

On the equivalence of N=1 brane worlds and geometric singularities with flux

We consider Kaluza Klein reductions of M-theory on the Z_N orbifold of the spin bundle over S^3 along two different U(1) isometries. The first one gives rise to the familiar ``large N duality'' of the N=1 SU(N) gauge theory in which the UV is realized as the world-volume theory of N D6-branes wrapped on S^3, whereas the IR involves N units of RR flux through an S^2. The second reduction gives an equivalent version of this duality in which the UV is realized geometrically in terms of an S^2 of A_{N-1} singularities, with one unit of RR flux through the S^2. The IR is reached via a geometric transition and involves a single D6 brane on a lens space S^3/Z_N or, alternatively, a singular background (S^2\times R^4)/Z_N, with one unit of RR flux through S^2 and, localized at the singularities, an action of their stabilizer group in the U(1) RR gauge bundle, so that no massless twisted states occur. We also consider linear sigma-model descriptions of these backgrounds.Comment: 25 pages, LaTeX; v2: one reference added, published versio

Phosphorylation of CENP-A on serine 7 does not control centromere function

CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal regions. In humans, several post-translational modifications occur on CENP-A, but their role in centromere function remains controversial. One of these modifications of CENP-A, phosphorylation on serine 7, has been proposed to control centromere assembly and function. Here, using gene targeting at both endogenous CENP-A alleles and gene replacement in human cells, we demonstrate that a CENP-A variant that cannot be phosphorylated at serine 7 maintains correct CENP-C recruitment, faithful chromosome segregation and long-term cell viability. Thus, we conclude that phosphorylation of CENP-A on serine 7 is dispensable to maintain correct centromere dynamics and function

320g Ionization-Heat Cryogenic Detector for Dark Matter Search in the EDELWEISS Experiment

The EDELWEISS experiment used in 2001 a 320g heat-and-ionization cryogenic Ge detector operated in a low-background environment in the Laboratoire Souterrain de Modane for direct WIMP detection. This detector presents an increase of more than 4 times the mass of previous detectors. Calibrations of this detector are used to determine its energy resolution and fiducial volume, and to optimize the detector design for the 1kg phase of the EDELWEISS-I experiment. Analysis of the calibrations and characteristics of a first series of 320g-detectors are presented.Comment: 4 pages, 3 figure

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly

Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere assembly have been completed in G1/S, continued CENP-A binding is not required for maintaining kinetochore attachment to centromeres or for centromere function in the next mitosis. Degradation of CENP-A prior to kinetochore assembly is found to block deposition of CENP-C and CENP-N, but not CENP-T, thereby producing defective kinetochores and failure of chromosome segregation. Without the continuing presence of CENP-A, CENP-B binding to alphoid DNA sequences becomes essential to preserve anchoring of CENP-C and the kinetochore to each centromere. Thus, there is a reciprocal interdependency of CENP-A chromatin and the underlying repetitive centromere DNA sequences bound by CENP-B in the maintenance of human chromosome segregation

A New Probe of the Planet-Forming Region in T Tauri Disks

We present new observations of the FUV (1100-2200 Angstrom) radiation field and the near- to mid-IR (3--13.5 micron) spectral energy distribution (SED) of a sample of T Tauri stars selected on the basis of bright molecular disks (GM Aur, DM Tau, LkCa15). In each source we find evidence for Ly alpha induced H2 fluorescence and an additional source of FUV continuum emission below 1700 Angstroms. Comparison of the FUV spectra to a model of H2 excitation suggests that the strong continuum emission is due to electron impact excitation of H2. The ultimate source of this excitation is likely X-ray irradiation which creates hot photo-electrons mixed in the molecular layer. Analysis of the SED of each object finds the presence of inner disk gaps with sizes of a few AU in each of these young (~1 Myr) stellar systems. We propose that the presence of strong H2 continuum emission and inner disk clearing are related by the increased penetration power of high energy photons in gas rich regions with low grain opacity.Comment: 5 pages, 3 figures, accepted by ApJ Letter