15,142 research outputs found

    Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms.

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    Staphylococcus aureus biofilms are a significant problem in health care settings, partly due to the presence of a nondividing, antibiotic-tolerant subpopulation. Here we evaluated treatment of S. aureus UAMS-1 biofilms with HT61, a quinoline derivative shown to be effective against nondividing Staphylococcus spp. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections

    A cross-cultural study of mood in K-POP Songs

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    Prior research suggests that music mood is one of the most important criteria when people look for music – but the perception of mood may be subjective and can be influenced by many factors including the listeners’ cultural background. In recent years, the number of studies of music mood perceptions by various cultural groups and of automated mood classification of music from different cultures has been increasing. However, there has yet to be a well-established testbed for evaluating cross-cultural tasks in Music Information Retrieval (MIR). Moreover, most existing datasets in MIR consist mainly of Western music and the cultural backgrounds of the annotators were mostly not taken into consideration or were limited to one cultural group. In this study, we built a collection of 1,892 K-pop (Korean Pop) songs with mood annotations collected from both Korean and American listeners, based on three different mood models. We analyze the differences and similarities between the mood judgments of the two listener groups, and propose potential MIR tasks that can be evaluated on this dataset. © Xiao Hu, Jin Ha Lee, Kahyun Choi, J. Stephen Downie.published_or_final_versio

    Data Science as an Emerging Discipline: The Roles of iSchools in the Era of Big Data

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    Workshop 4b: Information Science to Data Science: New Directions for iSchools Part 2 of 2 - Session 2A: Collaborative and Interdisciplinary Nature of IS2DSHosts: Wuhan University School of Information Management and the Sungkyunkwan University Library & Information Science and Data Science DepartmentData science has been a hype in both academia and industry. It is a high time for iSchools to reflect the roles they are playing and how they can contribute in the data science space, specifically in the areas of education and research. This position paper reviews data science related teaching and research activities in tier 1 iSchools and discusses the potentials of iSchools in shaping up the future of Data science.published_or_final_versio

    Use of a Chemical-Looping Reaction to Determine the Residence Time Distribution of Solids in a Circulating Fluidized Bed

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    The residence time distribution (RTD) of solids in various sections of a circulating fluidized bed (CFB) is of great importance for design and operation but is often difficult to determine experimentally. A noninvasive method is described, for which the RTD was derived from temporal measurements of the temperature following the initiation of a chemical-looping reaction. To demonstrate the method, a CuO-based oxygen carrier was used in a small-scale CFB, and measurements were made in the fuel reactor, operated as a bubbling fluidized bed. The measurements were fitted to the tanks-in-series model, modified to account for heat losses from the reactor. There was excellent agreement between the model and the experiment. Limitations and further improvements of the method are discussed, also with respect to larger reactors.This work is supported by the Engineering and Physical Sciences Research Council (EPSRC Grant EP/I010912/1).This is the final version of the article. It first appeared from Wiley via http://dx.doi.org/10.1002/ente.20160014

    WiMIR: An Informetric Study on Women Authors in ISMIR

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    Poster session 3: paper no. PS3-29Organized by New York University and Columbia UniversityThe Music Information Retrieval (MIR) community is becoming increasingly aware of a gender imbalance evident in ISMIR participation and publication. This paper reports upon a comprehensive informetric study of the publication, authorship and citation characteristics of female researchers in the context of the ISMIR conferences. All 1,610 papers in the ISMIR proceedings written by 1,910 unique authors from 2000 to 2015 were collected and analyzed. Only 14.1% of all papers were led by female researchers. Temporal analysis shows that the percentage of lead female authors has not improved over the years, but more papers have appeared with female coauthors in very recent years. Topics and citation numbers are also analyzed and compared between female and male authors to identify research emphasis and to measure impact. The results show that the most prolific authors of both genders published similar numbers of ISMIR papers and the citation counts of lead authors in both genders had no significant difference. We also analyzed the collaboration patterns to discover whether gender is related to the number of collaborators. Implications of these findings are discussed and suggestions are proposed on how to continue encouraging and supporting female participation in the MIR field.published_or_final_versio

    Exploration of the material property space for chemical looping air separation applied to carbon capture and storage

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    Oxy-fuel combustion is one route to large scale carbon capture and storage. Fuel is combusted in oxygen rather than air, allowing pure CO2 to be captured and sequestered. Currently, the required oxygen is produced via cryogenic air separation, which imposes a significant energy penalty. Chemical looping air separation (CLAS) is an alternative process for the production of oxygen, and relies on the repeated oxidation and reduction of solid oxygen carriers (typically metal oxides). The energy efficiency is governed by the thermodynamic properties of the oxygen carrier material, and how well the CLAS process can be heat-integrated with the process consuming oxygen. In this study, key thermodynamic properties have been identified and assessed using a steady state model of a CLAS-oxy-fuel power plant. It is demonstrated that energy penalties as low as 1.5 percentage points can be obtained for a narrow range of material properties. Based on density functional theory calculations, 14 oxygen carrier systems, which are novel or have received little attention, have been identified that could potentially achieve this minimal energy penalt

    Microstructures and resistivity of cuprate/manganite bilayer deposited on SrTiO3 substrate

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    Thin Yba[SUB2]Cu[SUB3]O[SUB7-δ/La[SUB0.67]Ca[SUB0.33]MnO[SUB3] (YBCO/LCMO) films were grown on SrTiO[SUB3](STO)substrates by magnetron sputtering technique. The microstructures of the bilayers were characterized and a standard four-probe technique was applied to measure the resistivity of the samples. The interdiffusions at the YBCO/LCMO and LCMO/STO interfaces formed two transient layers with the thickness of about 3 and 2 nm, respectively. All the bilayers were well textured along the c axis. At low temperature, the superconductivity can only be observed when the thickness of YBCO is more than 25 nm. When the thickness of YBCO is less than 8 nm, the bilayers show only ferromagnetism. The superconductivity and ferromagnetism perhaps coexist in the bilayer with the YBCO thickness of 12.5 nm. These interesting properties are related to the interaction between spin polarized electrons in the manganites and the cooper pairs in the cuprates. © 2003 American Institute of Physics.published_or_final_versio

    The conceptualisation and measurement of DSM-5 Internet Gaming Disorder: the development of the IGD-20 Test

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    Background: Over the last decade, there has been growing concern about ‘gaming addiction’ and its widely documented detrimental impacts on a minority of individuals that play excessively. The latest (fifth) edition of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-5) included nine criteria for the potential diagnosis of Internet Gaming Disorder (IGD) and noted that it was a condition that warranted further empirical study. Aim: The main aim of this study was to develop a valid and reliable standardised psychometrically robust tool in addition to providing empirically supported cut-off points. Methods: A sample of 1003 gamers (85.2% males; mean age 26 years) from 57 different countries were recruited via online gaming forums. Validity was assessed by confirmatory factor analysis (CFA), criterion-related validity, and concurrent validity. Latent profile analysis was also carried to distinguish disordered gamers from non-disordered gamers. Sensitivity and specificity analyses were performed to determine an empirical cut-off for the test. Results: The CFA confirmed the viability of IGD-20 Test with a six-factor structure (salience, mood modification, tolerance, withdrawal, conflict and relapse) for the assessment of IGD according to the nine criteria from DSM-5. The IGD-20 Test proved to be valid and reliable. According to the latent profile analysis, 5.3% of the total participants were classed as disordered gamers. Additionally, an optimal empirical cut-off of 71 points (out of 100) seemed to be adequate according to the sensitivity and specificity analyses carried
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