FLOSSTV Free, Libre, Open Source Software (FLOSS) within participatory 'TV hacking' Media and Arts Practices

This research operates in the context of a European political discourse, where the main concern is counter­cultural approaches to non­ mandatory collaboration and contractual agreements. FLOSSTV (Free, Libre, Open Source Software TV) covers a broad range of practices, from television via documentary up to media arts productions. This thesis documents the endeavour to formulate a policy for FLOSS culture. FLOSSTV studies the impact of new intellectual property legislation on media production, as well as conceptions and applications of collective authorship and alternative licensing schemes. FLOSSTV sets out to explore methods that can facilitate media and arts practitioners wishing to engage in collaborative media productions. The thesis sets out to investigate the theories and histories of collaborative media and arts productions in order to set the ground for an exploration of the tools, technologies and aesthetics of such collaborations. The FLOSSTV thesis proposes a set of contracts and policies that allow for such collaborations to develop. It is through practice that this research explores FLOSS culture, including its methods, licensing schemes and technologies. In order to focus the research within the field of FLOSSTV I initiated the practice ­based Deptford.TV pilot project as the central research experiment for the FLOSSTV thesis. DVD ONE contains a series of films produced collaboratively for Deptford.TV that express the characteristics and contractual arrangements of FLOSS culture. Deptford.TV is an online audiovisual database primarily collecting media assets around the Deptford area, in South­East London, UK. Deptford.TV functions as an open, collaborative platform that allows artists, film­makers, researchers and participants of the local workshops in and around Deptford, and also beyond Deptford, to store, share, re­edit and redistribute their footage and projects. The open and collaborative nature of the Deptford.TV project demonstrates a form of shared media practice in two ways: audiences become producers by submitting their own footage, and the database enables the contributors to interact with each other. Through my practice­lead research project Deptford.TV I argue that, by supporting collaborative methods and practices, FLOSS (Free, Libre, Open Source Software) can empower media and arts practitioners to collaborate in production and distribution processes of media and arts practices

A PRELIMINARY STUDY OF THE PALEOLITHIC AND NEOLITHIC CONTRIBUTION THE EUROPEAN MTDNA FLOW IN SHAPING THE GENETIC STRUCTURE OF RECENT BOSNIAN POPULATION

The mitochondrial DNA (mtDNA) polymorphisms in Bosnian human population was analyzed by means of hypervariable segment I and II (HVSI and HVSII) sequencing and restriction fragment-length polymorphism analysis of the mtDNA coding region. The results suggest that shaping the genetic structure of recent Bosnian population likely to be affected by the expansion from the European glacial refuges area at the end of the Last Glacial Maximum (LGM), postglacial expansions from southwestern refuges of Europe, the Italian Peninsula and the dispersion in periods of more recent historical events, from the East European Plain. Especially interesting feature of the Neolithic expansion in this area is the ancient African/South Asian haplogroup N1a with the HVSI variant 16147G, which is almost absent in Europe. The haplotyps HVSI with variant 16147G suggest the colonization of the Northeast Bosnia region by Neolithic communities in the Early Neolithic period of expansion through Europe, as evidenced by the archaeological remains of the Starcevo culture

Erasmus XR - immersive experiences in European academic institutions

This paper discusses the Erasmus XR project which responds to the urgent need to enrich the existing educational programs for both cultural and media managers, but also for artists aspiring to connect with their audiences in the digital space. The project’s overall goal is to develop an educational offer for these groups in the field of immersive media (XR), and ways of using these media to engage audiences. More specifically, the project aims at increasing the skills and competences of the participants in designing and evaluating immersive experiences in order to effectively manage, disseminate, and produce culture in the digital sphere.peer-reviewe

Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory

The Ras GTPase activating proteins (RasGAPs) are regulators of the conserved Ras/MAPK pathway. Various roles of some of the RasGAPs in learning and memory have been reported in different model systems, yet, there is no comprehensive study to characterize all gap genes in any organism. Here, using reverse genetics and neurobehavioural tests, we studied the role of all known genes of the rasgap family in C. elegans in associative learning and memory. We demonstrated that their proteins are implicated in different parts of the learning and memory processes. We show that gap-1 contribute redundantly with gap-3 to the chemosensation of volatile compounds, gap-1 plays a major role in associative learning, while gap-2 and gap-3 are predominantly required for short- and long-term associative memory. Our results also suggest that the C. elegans Ras orthologue let-60 is involved in multiple processes during learning and memory. Thus, we show that the different classes of RasGAP proteins are all involved in cognitive function and their complex interplay ensures the proper formation and storage of novel information in C. elegans

Alternative splicing: a potential therapeutic target in hematological malignancies

Leukemia represents the most prevalent malignancy in children, constituting 30% of childhood cancer cases, with acute lymphoblastic leukemia (ALL) being particularly heterogeneous. This paper explores the role of alternative splicing in leukemia, highlighting its significance in cancer development and progression. Aberrant splicing is often driven by mutations in splicing-factor genes, which can lead to the production of variant proteins that contribute to oncogenesis. The spliceosome, a complex of small nuclear RNAs and proteins, facilitates RNA splicing, a process critical for generating diverse mRNA and protein products from single genes. Mutations in splicing factors, such as U2AF1, SF3B1, SRSF2, ZRSR2, and HNRNPH1, are frequently observed across various hematological malignancies and are associated with poor prognosis and treatment resistance. This research underscores the necessity of understanding the mechanisms of RNA splicing dysregulation in order to develop targeted therapies to correct these aberrant processes, thereby improving outcomes for patients with leukemia and related disorders

Investigational Anti SARS-COVID 19 Medication

The newly identified severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) that originated in December 2019 in Wuhan, China. By July 2020, the WHO reported over 17 million confirmed cases in over 200 countries around the globe. This review discusses how the COVID-19 pandemic may affect healthy people, structure and replication cycle of SARS- CoV-2; targets and therapeutics SARS- CoV-2 and anti-COVID drugs: strategies and perspectives