2,216 research outputs found

    Three Letter Words: OMG

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    A magazine by 'Publish and be Damned' related to the fringes of publishing edited by myself (with Kate Phillimore and Louise O'hare). Including my interview with slash fiction founder 'Della Van Hise' and my review of 'Seeing is Believing', Kunst Werke

    Hannes Zebedin: Living in Glass Houses

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    Catalogue essay for Hannes Zebedin exhibition at Secession, Vienna. The essay explores Zebedin's work in relationship to civic life and third sector economies

    Games & Theory

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    ‘Games & Theory’ was an international exhibition of the work of contemporary artists who share interests in play, sports and gaming. It was curated by Hammonds for the South London Art Gallery (SLG) in summer 2008. Conventionally, play is understood as unfettered creative freedom, while gaming addresses competition and strategy. The exhibition’s originality lay in the way it brought these two distinct theories into dialogue. Hammonds’s exhibition explored the proposition that, as a social practice, play can also be understood as a form of political negotiation. Taking its cue from Situationist thinking, the exhibition explored the radical potential of play as a form of resistance and expression of freedom. The exhibition was structured as a playground to test the extent to which the conventional spaces of the gallery and its immediate environment could be modified and extended. ‘Games & Theory’ also engaged with the challenge of examining the ways in which conventional art practices and objects – such as painting – could be modified by participatory practices associated with play. This was one of a series of projects curated by Hammonds at the SLG that transformed the gallery into an alternative social space. The exhibition marked the starting point of a three-year programme of ‘play’ within the SLG’s programme. Hammonds set these curatorial ideas in a critical and artistic context in an essay entitled ‘Games people play’ in the accompanying book, The Cat Came as a Tomato: Conversations on Contemporary Art and Play (2011). In it, Hammonds reflected on the ways in which art has been conventionally grouped with play to contain it outside the public/political space. The exhibition was reviewed in Frieze, Art Monthly, Time Out and Art Review (all 2008)

    World Bank policies and the obligation of its members to respect, protect and fulfil the right to health

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    The majority of World Bank donors are States parties to the main inter-national human rights conventions. This article uses the right to health as a lens for examining the obligations of donor States parties with re-spect to their involvement in the World Bank's development activities, which use the Poverty Reduction Strategy Paper (PRSP) process as their framework. The article uses the concept of core obligations to examine and assess public expenditure budgeting in the health care sectors of Mozambique, Rwanda, and Uganda, as provided for in the PRSP process. It argues that the current PRSPs make it impossible to fund public health care at a level that satisfies the requirements of core obligations. It concludes by calling on donor countries to comply with their interna-tional human rights obligations

    Ground Level

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    Exhibition catalogue from the touring show 'Ground Level' - Hayward Touring Curatorial Open 2010. The exhibition explored artists using cartographic processes, and the catalogue essay explores the relationship between experience of a landscape and its abstraction in mapping. The exhibition itself addressed notions of displaying artists practice as research rather than art object

    Rigid unit modes in tetrahedral crystals

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    The 'rigid unit mode' (RUM) model requires unit blocks, in our case tetrahedra of SiO_4 groups, to be rigid within first order of the displacements of the O-ions. The wave-vectors of the lattice vibrations, which obey this rigidity, are determined analytically. Lattices with inversion symmetry yield generically surfaces of RUMs in reciprocal space, whereas lattices without this symmetry yield generically lines of RUMs. Only in exceptional cases as in beta-quartz a surface of RUMs appears, if inversion symmetry is lacking. The occurence of planes and bending surfaces, straight and bent lines is discussed. Explicit calculations are performed for five modifications of SiO_2 crystals.Comment: 18 pages, 6 figures, improved notatio

    The emergence of a global right to health norm--the unresolved case of universal access to quality emergency obstetric care.

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    BACKGROUND: The global response to HIV suggests the potential of an emergent global right to health norm, embracing shared global responsibility for health, to assist policy communities in framing the obligations of the domestic state and the international community. Our research explores the extent to which this global right to health norm has influenced the global policy process around maternal health rights, with a focus on universal access to emergency obstetric care. METHODS: In examining the extent to which arguments stemming from a global right to health norm have been successful in advancing international policy on universal access to emergency obstetric care, we looked at the period from 1985 to 2013 period. We adopted a qualitative case study approach applying a process-tracing methodology using multiple data sources, including an extensive literature review and limited key informant interviews to analyse the international policy agenda setting process surrounding maternal health rights, focusing on emergency obstetric care. We applied John Kingdon's public policy agenda setting streams model to analyse our data. RESULTS: Kingdon's model suggests that to succeed as a mobilising norm, the right to health could work if it can help bring the problem, policy and political streams together, as it did with access to AIDS treatment. Our analysis suggests that despite a normative grounding in the right to health, prioritisation of the specific maternal health entitlements remains fragmented. CONCLUSIONS: Despite United Nations recognition of maternal mortality as a human rights issue, the relevant policy communities have not yet managed to shift the policy agenda to prioritise the global right to health norm of shared responsibility for realising access to emergency obstetric care. The experience of HIV advocates in pushing for global solutions based on right to health principles, including participation, solidarity and accountability; suggest potential avenues for utilising right to health based arguments to push for policy priority for universal access to emergency obstetric care in the post-2015 global agenda

    Global constitutionalism, applied to global health governance: uncovering legitimacy deficits and suggesting remedies.

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    BACKGROUND: Global constitutionalism is a way of looking at the world, at global rules and how they are made, as if there was a global constitution, empowering global institutions to act as a global government, setting rules which bind all states and people. ANALYSIS: This essay employs global constitutionalism to examine how and why global health governance, as currently structured, has struggled to advance the right to health, a fundamental human rights obligation enshrined in the International Covenant on Economic, Social and Cultural Rights. It first examines the core structure of the global health governance architecture, and its evolution since the Second World War. Second, it identifies the main constitutionalist principles that are relevant for a global constitutionalism assessment of the core structure of the global health governance architecture. Finally, it applies these constitutionalist principles to assess the core structure of the global health governance architecture. DISCUSSION: Leading global health institutions are structurally skewed to preserve high incomes countries' disproportionate influence on transnational rule-making authority, and tend to prioritise infectious disease control over the comprehensive realisation of the right to health. CONCLUSION: A Framework Convention on Global Health could create a classic division of powers in global health governance, with WHO as the law-making power in global health governance, a global fund for health as the executive power, and the International Court of Justice as the judiciary power

    Fluorescence-based incision assay for human XPF-ERCC1 activity identifies important elements of DNA junction recognition

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    The structure-specific endonuclease activity of the human XPF–ERCC1 complex is essential for a number of DNA processing mechanisms that help to maintain genomic integrity. XPF–ERCC1 cleaves DNA structures such as stem–loops, bubbles or flaps in one strand of a duplex where there is at least one downstream single strand. Here, we define the minimal substrate requirements for cleavage of stem–loop substrates allowing us to develop a real-time fluorescence-based assay to measure endonuclease activity. Using this assay, we show that changes in the sequence of the duplex upstream of the incision site results in up to 100-fold variation in cleavage rate of a stem-loop substrate by XPF-ERCC1. XPF–ERCC1 has a preference for cleaving the phosphodiester bond positioned on the 3′-side of a T or a U, which is flanked by an upstream T or U suggesting that a T/U pocket may exist within the catalytic domain. In addition to an endonuclease domain and tandem helix–hairpin–helix domains, XPF has a divergent and inactive DEAH helicase-like domain (HLD). We show that deletion of HLD eliminates endonuclease activity and demonstrate that purified recombinant XPF–HLD shows a preference for binding stem–loop structures over single strand or duplex alone, suggesting a role for the HLD in initial structure recognition. Together our data describe features of XPF–ERCC1 and an accepted model substrate that are important for recognition and efficient incision activity
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