96 research outputs found
Marriage and Educational Attainment: A Dynamic Approach to First Union Formation
The article looks at the relationship between partnership formation & women's education in the Czech Republic. Education can serve as a proxy for cultural capital & earning potential. Therefore, it is expected to play a significant role in partnership formation. Analyses of data from the Family & Fertility Survey show that the level of education has an impact on the timing of the first union. However, when school enrollment is controlled, education does not play a significant role in the tendency to enter into marriage or cohabitation. It is not possible to demonstrate that the accumulation of human capital itself has an impact on union formation in the Czech Republic. Nor do data confirm the expectation that the influence of education should increase after the collapse of communism & the introduction of the market economy
Marriage and Cohabitation: Qualitative Differences in Partnership Arrangements
The article investigates the differences between marriage & nonmarital cohabitation. The main perspective stems from the theory of the social exchange. The author concentrates on the narrow question of financial transfers between partners & presents the hypothesis that cohabitation should represent a lesser bond union because it does not protect investments into partnerships, & it should therefore be more egalitarian. However, this hypothesis is not confirmed by the data. Even though cohabitation is indeed a departure from the traditional family pattern, it is not a departure in the direction of greater egalitarianism but rather in the direction of a female breadwinner. The social exchange theory would predict that the shift towards the female breadwinner should be compensated by the greater participation of men in the household chores. This expectation is confirmed by the data
Životní spokojenost, štěstí a rodinný stav v 21 evropských zemích
The article focuses on the relationship between marital status & life satisfaction in the countries of Europe. The first part of the article discusses subjective evaluations of life satisfaction & the theoretical concepts that explain differences in the levels of life satisfaction according to marital status. The second part of the article is devoted to empirical analyses of data from the European Social Survey (ESS), the results of which indicate that in the countries studied married people tend to be more satisfied with life than others, even though the strength of this effect varies. The differences in the effect of marriage cannot be ascribed to a given society's divorce rate. In some countries the life satisfaction of the cohabiting population is almost as high as for married people, while in other countries it is closer to the level of life satisfaction observed among single people, & in other countries the level of satisfaction of the cohabitating individuals lies midway between married & single people
1H NMR relaxometry in the TGBA* and TGBC* phases
Recent results obtained by 1H NMR relaxometry of liquid crystals having twist grain boundary (TGB) phases are here reviewed. In
particular, three chiral rod-like lactate derivative mesogens were investigated. In the isotropic phase, three-exponential magnetization
decay was observed in all cases and the three distinct spin-lattice relaxation times (T1) were assigned to three specific molecular groups
of these molecules. In the TGBA* and TGBC* phases the magnetization decay is mono-exponential and the main features of the 1H NMR
dispersion curves analyzed through a global target fitting procedure in terms of specific molecular and collective dynamics are discussed
Differential lipid dependence of the function of bacterial sodium channels
The lipid bilayer is important for maintaining the integrity of cellular compartments and plays a vital role in providing the hydrophobic and charged interactions necessary for membrane protein structure, conformational flexibility and function. To directly assess the lipid dependence of activity for voltage-gated sodium channels, we compared the activity of three bacterial sodium channel homologues (NaChBac, NavMs, and NavSp) by cumulative 22Na+ uptake into proteoliposomes containing a 3:1 ratio of 1-palmitoyl 2-oleoyl phosphatidylethanolamine and different “guest” glycerophospholipids. We observed a unique lipid profile for each channel tested. NavMs and NavSp showed strong preference for different negatively-charged lipids (phosphatidylinositol and phosphatidylglycerol, respectively), whilst NaChBac exhibited a more modest variation with lipid type. To investigate the molecular bases of these differences we used synchrotron radiation circular dichroism spectroscopy to compare structures in liposomes of different composition, and molecular modeling and electrostatics calculations to rationalize the functional differences seen. We then examined pore-only constructs (with voltage sensor subdomains removed) and found that in these channels the lipid specificity was drastically reduced, suggesting that the specific lipid influences on voltage-gated sodium channels arise primarily from their abilities to interact with the voltage-sensing subdomains
Tolerability and safety of fluvoxamine and other antidepressants
Selective serotonin [5-hydroxytryptamine (5-HT)] reuptake inhibitors (SSRIs) and the 5-HT noradrenaline reuptake inhibitor, venlafaxine, are mainstays in treatment for depression. The highly specific actions of SSRIs of enhancing serotonergic neurotransmission appears to explain their benefit, while lack of direct actions on other neurotransmitter systems is responsible for their superior safety profile compared with tricyclic antidepressants. Although SSRIs (and venlafaxine) have similar adverse effects, certain differences are emerging. Fluvoxamine may have fewer effects on sexual dysfunction and sleep pattern. SSRIs have a cardiovascular safety profile superior to that of tricyclic antidepressants for patients with cardiovascular disease; fluvoxamine is safe in patients with cardiovascular disease and in the elderly. A discontinuation syndrome may develop upon abrupt SSRI cessation. SSRIs are more tolerable than tricyclic antidepressants in overdose, and there is no conclusive evidence to suggest that they are associated with an increased risk of suicide. Although the literature suggests that there are no clinically significant differences in efficacy amongst SSRIs, treatment decisions need to be based on considerations such as patient acceptability, response history and toxicity
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