3,607 research outputs found
Canadian / U.S. Exchange Rates and Nonresident Investors: Their Influence on Residential Property Values
Factors external to a home’s characteristics may influence the sales price. This analysis focuses on Bellingham, Washington, because of several influences including the Canadian economy and nonresidents. First estimated is a constant-quality Bellingham housing price index, which is used as the dependent variable in a reduced-form model of market price to estimate the impact of the exchange rate. The analysis (1984-94) suggests that a 10% rise in the exchange rate leads to a 7.7% rise in Bellingham home prices. Additionally, in 1990, non-county buyers paid 4% to 6% more than county residents and non-county sellers received 6% to 8% less.
The Influence of Canadian Investment on U.S. Residential Property Values
This study is an examination of the impact of foreign investors on an American residential real estate market. Point Roberts, Washington, a real estate market that is dominated by Canadians, is the focus of the analysis. Utilizing a ten-year database of home sales, the empirical analysis suggests that the Canadian/U.S. dollar exchange rate and market conditions in nearby Vancouver, British Columbia, strongly influence Point Roberts residential property price levels. A rising Canadian dollar seems to motivate increased demand for Point Roberts property by Canadian investors, for example. The sensitivity of real estate prices to exchange-rate changes appears to be a three-to-six-month lagged function. In general, it appears that a higher Canadian dollar will increase the Canadian demand for Point Roberts real estate which, in turn, leads to higher transaction prices. In addition, transaction prices in Point Roberts are slightly more volatile than are prices in the Vancouver market.
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Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
How pathogenic cluster of differentiation 4 (CD4) T cells in rheumatoid arthritis (RA) develop remains poorly understood. We used Nur77-a marker of T cell antigen receptor (TCR) signaling-to identify antigen-activated CD4 T cells in the SKG mouse model of autoimmune arthritis and in patients with RA. Using a fluorescent reporter of Nur77 expression in SKG mice, we found that higher levels of Nur77-eGFP in SKG CD4 T cells marked their autoreactivity, arthritogenic potential, and ability to more readily differentiate into interleukin-17 (IL-17)-producing cells. The T cells with increased autoreactivity, nonetheless had diminished ex vivo inducible TCR signaling, perhaps reflective of adaptive inhibitory mechanisms induced by chronic autoantigen exposure in vivo. The enhanced autoreactivity was associated with up-regulation of IL-6 cytokine signaling machinery, which might be attributable, in part, to a reduced amount of expression of suppressor of cytokine signaling 3 (SOCS3)-a key negative regulator of IL-6 signaling. As a result, the more autoreactive GFPhi CD4 T cells from SKGNur mice were hyperresponsive to IL-6 receptor signaling. Consistent with findings from SKGNur mice, SOCS3 expression was similarly down-regulated in RA synovium. This suggests that despite impaired TCR signaling, autoreactive T cells exposed to chronic antigen stimulation exhibit heightened sensitivity to IL-6, which contributes to the arthritogenicity in SKG mice, and perhaps in patients with RA
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A framework for the simulation of regional decadal variability for agricultural and other applications
Climate prediction on decadal time scales is currently an active area of research, and reliable model-based forecasts of regional "near-term" climate change have yet to be demonstrated. In the absence of such forecasts, synthetic data sequences that capture the statistical properties of observed near-term climate variability have potential value. Incorporation of a climate change component in such sequences can help define risk estimates for a range of climatic stresses, including those lying beyond what has been experienced in the past. Properly conditioned simulations can be used to drive agricultural, hydrological or other application models, enabling resilience testing of adaptation or decision systems. The use of statistically-based methods enables the efficient generation of large ensembles of synthetic sequences and consequently, the creation of well-defined probabilistic risk estimates. In this report we examine some procedures for the generation of synthetic climate sequences that incorporate both the statistics of observed variability and expectations regarding future regional climate change. Model fitting and simulation are considered in the framework of classical time series analysis, with methodology conditioned by requirements particular to the decadal climate problem. A method of downscaling annualized simulations to the daily time step, while preserving subannual statistical properties, is presented and other possible methods discussed. Deployment in the applications setting, the details of which may vary considerably, depending on regional climate characteristics, available data and the design of follow-on models, is considered and elements of a case study presented
Diffusion of renewable energy technologies: Case studies of enabling frameworks in developing countries
Model for the hydration of non-polar compounds and polymers
We introduce an exactly solvable statistical-mechanical model of the
hydration of non-polar compounds, based on grouping water molecules in clusters
where hydrogen bonds and isotropic interactions occur; interactions between
clusters are neglected. Analytical results show that an effective strengthening
of hydrogen bonds in the presence of the solute, together with a geometric
reorganization of water molecules, are enough to yield hydrophobic behavior. We
extend our model to describe a non-polar homopolymer in aqueous solution,
obtaining a clear evidence of both ``cold'' and ``warm'' swelling transitions.
This suggests that our model could be relevant to describe some features of
protein folding.Comment: REVTeX, 6 pages, 3 figure
Southern Cosmology Survey I: Optical Cluster Detections and Predictions for the Southern Common-Area Millimeter-Wave Experiments
We present first results from the Southern Cosmology Survey, a new
multiwavelength survey of the southern sky coordinated with the Atacama
Cosmology Telescope (ACT), a recently commissioned ground-based mm-band Cosmic
Microwave Background experiment. This article presents a full analysis of
archival optical multi-band imaging data covering an 8 square degree region
near right ascension 23 hours and declination -55 degrees, obtained by the
Blanco 4-m telescope and Mosaic-II camera in late 2005. We describe the
pipeline we have developed to process this large data volume, obtain accurate
photometric redshifts, and detect optical clusters. Our cluster finding process
uses the combination of a matched spatial filter, photometric redshift
probability distributions and richness estimation. We present photometric
redshifts, richness estimates, luminosities, and masses for 8 new
optically-selected clusters with mass greater than 3\times10^{14}M_{\sun} at
redshifts out to 0.7. We also present estimates for the expected
Sunyaev-Zel'dovich effect (SZE) signal from these clusters as specific
predictions for upcoming observations by ACT, the South Pole Telescope and
Atacama Pathfinder Experiment.Comment: 12 pages, 8 figures, accepted in ApJ. Reflects changes from referee
as well as a new Table providing mass estimates and positions for all
clusters in the surve
MycoBank gearing up for new horizons.
MycoBank, a registration system for fungi established in 2004 to capture all taxonomic novelties, acts as a coordination hub between repositories such as Index Fungorum and Fungal Names. Since January 2013, registration of fungal names is a mandatory requirement for valid publication under the International Code of Nomenclature for algae, fungi and plants (ICN). This review explains the database innovations that have been implemented over the past few years, and discusses new features such as advanced queries, registration of typification events (MBT numbers for lecto, epi- and neotypes), the multi-lingual database interface, the nomenclature discussion forum, annotation system, and web services with links to third parties. MycoBank has also introduced novel identification services, linking DNA sequence data to numerous related databases to enable intelligent search queries. Although MycoBank fills an important void for taxon registration, challenges for the future remain to improve links between taxonomic names and DNA data, and to also introduce a formal system for naming fungi known from DNA sequence data only. To further improve the quality of MycoBank data, remote access will now allow registered mycologists to act as MycoBank curators, using Citrix software
Letter from Arthur W. Hansen
Letter concerning a position in department of chemistry at Utah Agricultural College
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