Suicide risk in schizophrenia: learning from the past to change the future

Suicide is a major cause of death among patients with schizophrenia. Research indicates that at least 5–13% of schizophrenic patients die by suicide, and it is likely that the higher end of range is the most accurate estimate. There is almost total agreement that the schizophrenic patient who is more likely to commit suicide is young, male, white and never married, with good premorbid function, post-psychotic depression and a history of substance abuse and suicide attempts. Hopelessness, social isolation, hospitalization, deteriorating health after a high level of premorbid functioning, recent loss or rejection, limited external support, and family stress or instability are risk factors for suicide in patients with schizophrenia. Suicidal schizophrenics usually fear further mental deterioration, and they experience either excessive treatment dependence or loss of faith in treatment. Awareness of illness has been reported as a major issue among suicidal schizophrenic patients, yet some researchers argue that insight into the illness does not increase suicide risk. Protective factors play also an important role in assessing suicide risk and should also be carefully evaluated. The neurobiological perspective offers a new approach for understanding self-destructive behavior among patients with schizophrenia and may improve the accuracy of screening schizophrenics for suicide. Although, there is general consensus on the risk factors, accurate knowledge as well as early recognition of patients at risk is still lacking in everyday clinical practice. Better knowledge may help clinicians and caretakers to implement preventive measures. This review paper is the results of a joint effort between researchers in the field of suicide in schizophrenia. Each expert provided a brief essay on one specific aspect of the problem. This is the first attempt to present a consensus report as well as the development of a set of guidelines for reducing suicide risk among schizophenia patients

PASTRAMI: Privacy-preserving, Auditable, Scalable & Trustworthy Auctions for Multiple Items

Decentralised cloud computing platforms enable individuals to offer and rent resources in a peer-to-peer fashion. They must assign resources from multiple sellers to multiple buyers and derive prices that match the interests and capacities of both parties. The assignment process must be decentralised, fair and transparent, but also protect the privacy of buyers. We present PASTRAMI, a decentralised platform enabling trustworthy assignments of items and prices between a large number of sellers and bidders, through the support of multi-item auctions. PASTRAMI uses threshold blind signatures and commitment schemes to provide strong privacy guarantees while making bidders accountable. It leverages the Ethereum blockchain for auditability, combining efficient off-chain computations with novel, on-chain proofs of misbehaviour. Our evaluation of PASTRAMI using Filecoin workloads show its ability to efficiently produce trustworthy assignments between thousands of buyers and sellers

Electronic Auctions with Private Bids

Auctions are a fundamental electronic commerce technology. We describe a set of protocols for performing sealed-bid electronic auctions which preserve the privacy of the submitted bids using a form of secure distributed computation. Bids are never revealed to any party, even after the auction is completed. Both first-price and second-price (Vickrey) auctions are supported, and the computational costs of the methods are low enough to allow their use in many real-world auction situations. 1 Introduction Auctions are a fundamental technology for electronic commerce. They have been suggested as a technology for controlling allocation of bandwidth [5, 10] and are increasingly seen on the web. If we could have an ideal auction, what properties might we desire? Here are some desiderata (not a complete list) for an ideal auction: ffl Economic design --- we want the auction to be designed on solid economic principles and for participants to have incentives to bid as they truly value the item ..