Invasive salmonellosis by the very rare salmonella choleraesuis in a returning traveler on a tumor necrosis factor-α inhibitor

Salmonella choleraesuis is one of the least commonly reported nontyphoidal salmonellae in the United States, accounting for only 0.08% and ranking lower than 20th place among all human source salmonellosis reported to the CDC in 2009. In the state of Connecticut, only 12 cases have been reported since 1998 and our case is the only case since 2008. We report a case of invasive Salmonellosis caused by Salmonella choleraesuis in a patient on an antitumor necrosis factor-α agent (adalimumab) who recently returned from a trip to the Dominican Republic

Lunar material transport vehicle

The proposed vehicle, the Lunar Material Transport Vehicle (LMTV), has a mission objective of efficient lunar soil material transport. The LMTV was designed to meet a required set of performance specifications while operating under a given set of constraints. The LMTV is essentially an articulated steering, double-ended dump truck. The vehicle moves on four wheels and has two identical chassis halves. Each half consists of a chassis frame, a material bucket, two wheels with integral curvilinear synchronous motors, a fuel cell and battery arrangement, an electromechanically actuated dumping mechanism, and a powerful microprocessor. The vehicle, as designed, is capable of transporting up to 200 cu ft of material over a one mile round trip per hour. The LMTV is capable of being operated from a variety of sources. The vehicle has been designed as simply as possible with attention also given to secondary usage of components

Copper(II) and Nickel(II) Octabromo-tetrakis(pentafluorophenyl)Porphyrin Complexes

The copper and nickel complexes of 2,3,7,8,12,13,17, 18-octabromo-5,10,15,20-tetrakis(pentaftuorophenyl) porphyrin ({4,5,9,10,14,15,19,20-octabromo-2,7,12,17-tetrakis(pentaftuorophenyl)-21,22,23,24-tetraazapentacyclo[l6.2.1.1^(3,6).l^(8,11).l^(13,16)]tetracosa-l,3-(22),4,6,8(23),9,11,13(24),14,16,18(21),19-dodecaene }copper(II) 0.5-dichloromethane solvate and {4,5,9,10,14,15,19,20-octabromo-2,7,12,17-tetrakis(pentaftuorophenyl)-21,22,23,24-tetraazapentacyclo( 16.2.1.1^(3,6).l^(8,11).l^(13,16)]tetracosa-l,3(22),4,6,8(23),9,ll,13(24),14,16,18(21),19-dodecaene} nickel(II)0.5-dichloromethane solvate) form isostructural crystals. There is significant distortion from planarity of the porphyrin ring caused by the octabromo substituents interacting with the meso-pentafluorophenyl groups and with each other, with departures of the Br atoms from the plane defined by the four N atoms of up to 2.36 A. This tetrahedral distortion of the molecule does not result in any significant changes in bond distances from those in non-halogenated tetraphenylporphyrin complexes

A highly solvated zinc(II) tetrakis(pentafluorophenyl)-β-octabromoporphyrin

The title compound, {4,5,9,10,14,15,19,20-octabromo-2,7,12,17-tetrakis(pentafluorophenyl)-21,22,23,- 24-tetraazapentacyclo[16.2.1.1^(3,6).1^(8,11).1^(13,16)]tetracosa-1,3(21),4,6,8(22),9,11,13(23),14,16,18(24),19-dodecaene }zinc(II) (carbon tetrachloride, o-dichlorobenzene, acetone, methanol, water solvate) has a large tetrahedral distortion, with the Br atoms as much as 1.83 Å from the plane of the N atoms. The distortion affects primarily bond angles and bond torsion angles; bond distances in the molecule are normal. Several different solvents are incorporated into the crystal, providing a close (2.16 Å) O atom as an axial neighbor to Zn and a more distant (3.16 Å) Cl atom, in the opposite axial site

Copper(II) tetrakis(pentafluorophenyl)-β-octachloroporphyrin

The title compound, {4,5,9,10,14,15,19,20-octachloro-2,7,12, 17-tetrakis(pentafluorophenyl)-20,22,23,24- tetraazapentacyclo[l6.2.l.1^(3·6).l^(8·11).l^(13·16)]tetracosa-1,3(21),4,6,8(22),9,11, 13(23), 14, 16, 18(24), 19-dodecaene}copper(II)(CuTFPPC1_8)dichloromethane solvate, shows a large tetrahedral distortion or ruffling, with pairs of Cl atoms alternately averaging + 1.20 and -1.18 Å out of the plane of the four N atoms; the Cu atom is 0.01 Å out of the plane and the N atoms show a slight (±0.12 Å) tetrahedral distortion. A Cl atom of the solvent, at 3.515 (6) Å in an approximately axial position, is the closest non-bonded neighbor of the Cu atom

Measurement of Z-boson production and luminosity monitoring using 5.02 TeV and 13 TeV ATLAS Run-2 pp collision data

Two analyses involving Drell-Yan production using ATLAS Run-2 pp collision data are presented. First, the monitoring of luminosity at 60 second granularity using the Z-counting method is presented. This involves the selection of Z→ee and Z→µµ events combined with data-driven efficiency calculations and pileup dependent corrections from Monte Carlo. Comparisons of luminosity estimates are performed using the full Run-2 dataset from 2015-2018, where internal consistency is shown between of Z→ee and Z→µµ methods and year-dependent trends of size 1% are shown between Z-counting and the baseline ATLAS luminosity measurement. An additional study is performed to quantify statistical bias in the Z-counting methodology, which is observed to be negligible for most Run-2 conditions but can be as large as 2% when the instantaneous luminosity is low. Second, the measurement of a triple-differential Drell-Yan cross-section in mll, yll and cos(θCS) is presented. These measurements use the special low-µ runs from 2017 and 2018, constituting 256.8 pb-1 at √s = 5:02 TeV and 335.2 pb-1 at √s = 13 TeV. This includes the derivation of muon trigger efficiency scale factors, the estimation of multijet background contribution and the implementation of an unfolding procedure. The unfolded differential cross-sections are shown to be statistically limited in most analysis bins, and the inclusive fiducial cross-sections are shown to be limited by the luminosity uncertainty in the central-mass region

The effect of pregnancy and lactation on the iodine compounds in the tissues and plasma of the rat

An isotopic equilibrium method was employed, based on the chronic feeding of an 125I-labeled diet of known specific activity, to determine the distribution and quantitation of endogenously labeled iodine-containing compounds in the female rat at various periods during gestation and post-parturition. A decrease was associated with gestation in the total iodine, which was significant in all extrathyroidal tissues except the brain and muscle, and a fall in thyroxine concentration which was significant in all extrathyroidal tissues except the heart. The triiodothyronine level decreased from the control values in gestation but not as consistently. There was also a significant decrease in the total iodine and thyroxine in the plasma at this time. Concomitant with this fall in plasma iodinated compounds was a significant increase in the free thyroxine percentage. These changes were paralleled by an increased renal and fecal excretion of iodide. Total iodine, T4, T3, MIT and DIT all increased in the thyroid gland; however, these changes in the latter 3 compounds were statistically insignificant. These findings indicate that during gestation the body stores of iodinated compounds become depleted with the exception of the thyroid, which shows a greater than normal absolute concentration. A postulated increased T4 turnover rate, which could be due to a high maternal deiodination or placental thyroxine permeability and fetal deiodination, could account for the above observations. Following parturition, there was an excessive rebound of the iodinated compounds over an approximate 4 week period towards control values. In the lactating rat, these compounds remained below non-lactating levels until after weaning and then returned to the control levels rapidly. The total iodine levels in the plasma were extremely low during lactation and rose slowly as milk secretion decreased. These postpartum observations were for the most part statistically insignificant although they revealed a definite trend. These low levels of total iodine could be explained by the secretion of iodide by the mammary gland during lactation. There was an increased accumulation of total iodine, T4, T3, MIT and DIT by the thyroid gland during lactation. These data suggest an adaptation of the thyroid to the increased need for T4 to support or control the mammary glands

Detector Description and Performance for the First Coincidence Observations between LIGO and GEO

For 17 days in August and September 2002, the LIGO and GEO interferometer gravitational wave detectors were operated in coincidence to produce their first data for scientific analysis. Although the detectors were still far from their design sensitivity levels, the data can be used to place better upper limits on the flux of gravitational waves incident on the earth than previous direct measurements. This paper describes the instruments and the data in some detail, as a companion to analysis papers based on the first data.Comment: 41 pages, 9 figures 17 Sept 03: author list amended, minor editorial change

Search for Gravitational Waves from Primordial Black Hole Binary Coalescences in the Galactic Halo

We use data from the second science run of the LIGO gravitational-wave detectors to search for the gravitational waves from primordial black hole (PBH) binary coalescence with component masses in the range 0.2--$1.0 M_\odot$. The analysis requires a signal to be found in the data from both LIGO observatories, according to a set of coincidence criteria. No inspiral signals were found. Assuming a spherical halo with core radius 5 kpc extending to 50 kpc containing non-spinning black holes with masses in the range 0.2--$1.0 M_\odot$, we place an observational upper limit on the rate of PBH coalescence of 63 per year per Milky Way halo (MWH) with 90% confidence.Comment: 7 pages, 4 figures, to be submitted to Phys. Rev.

Analysis of LIGO data for gravitational waves from binary neutron stars

We report on a search for gravitational waves from coalescing compact binary systems in the Milky Way and the Magellanic Clouds. The analysis uses data taken by two of the three LIGO interferometers during the first LIGO science run and illustrates a method of setting upper limits on inspiral event rates using interferometer data. The analysis pipeline is described with particular attention to data selection and coincidence between the two interferometers. We establish an observational upper limit of $\mathcal{R}<$1.7 \times 10^{2}$per year per Milky Way Equivalent Galaxy (MWEG), with 90coalescence rate of binary systems in which each component has a mass in the range 1--3$M_\odot$.Comment: 17 pages, 9 figure