Wisconsin’s Environmental Public Health Tracking Network: Information Systems Design for Childhood Cancer Surveillance

In this article we describe the development of an information system for environmental childhood cancer surveillance. The Wisconsin Cancer Registry annually receives more than 25,000 incident case reports. Approximately 269 cases per year involve children. Over time, there has been considerable community interest in understanding the role the environment plays as a cause of these cancer cases. Wisconsin’s Public Health Information Network (WI-PHIN) is a robust web portal integrating both Health Alert Network and National Electronic Disease Surveillance System components. WI-PHIN is the information technology platform for all public health surveillance programs. Functions include the secure, automated exchange of cancer case data between public health–based and hospital-based cancer registrars; web-based supplemental data entry for environmental exposure confirmation and hypothesis testing; automated data analysis, visualization, and exposure–outcome record linkage; directories of public health and clinical personnel for role-based access control of sensitive surveillance information; public health information dissemination and alerting; and information technology security and critical infrastructure protection. For hypothesis generation, cancer case data are sent electronically to WI-PHIN and populate the integrated data repository. Environmental data are linked and the exposure–disease relationships are explored using statistical tools for ecologic exposure risk assessment. For hypothesis testing, case–control interviews collect exposure histories, including parental employment and residential histories. This information technology approach can thus serve as the basis for building a comprehensive system to assess environmental cancer etiology

Chapter Title Occupational Determinants of Cognitive Decline and Dementia AU2 AU1

U. Bültmann, J. Siegrist (eds.), Handbook of Disability, Work and Health, HandbookSeries in Occupational Health Sciences,Cognitive decline and dementia are major burden for our aging society. The pathological processes implicated in dementia seem to be active many years before the first clinical signs. The life-course approach aims to integrate the different biological, social, clinical, psychological, and environmental components that interact all along the lifetime of a person, factors which are major determinants of our cognitive aging. Some studies illustrate how occupation and occupational exposures affect later in life cognitive functioning or dementia occurrence. Higher occupational status, complex occupational roles, or jobs that are challenging seem to have a protective effect on cognitive functioning and dementia occurrence, even when controlling for education. Conversely, high-strain work and passive jobs that lack both sel