Racjonalność i skuteczność planowania na przykładzie gminnego programu profilaktyki i rozwiązywania problemów alkoholowych

In the system of legal sources, apart from typical acts of local law created in accordance with the provisions of the Constitution, there are also acts that do not fall within the constitutional standards of law, although they concern, among other things, important social and economic issues. Such documents (planning acts, programmes, or strategies), although enacted by resolutions, often fail to contain generally binding regulations. Although this does not prevent them from having a binding force, they should nevertheless be made in compliance with the generally recognised rules of lawmaking, including the principles of proportionality, rationality, communicativeness and brevity. The generally applicable provisions often impose on local self-governments an obligation to create acts regulating important social issues, such as for instance programmes preventing and solving alcohol-related problems and determining the way of dealing with alcohol addiction in local conditions. However, these programmes are often developed in violation of the rules of a rational law-making process, and are frequently detached from the local reality, which makes them ineffective. Therefor it may be worth considering another way of responding to the problem of alcoholism, not necessarily by means of resolutions adopted annually. The obligation to develop a prevention and resolution programme addressing alcohol-related problems could be replaced, for example, by certain specific organisational measures, an educational programme, or the implementation of other measures. The law is not always the right way to achieve the goals set, but the above recommendation will requires statutory changes first, anyway.W systemie źródeł prawa wyróżnić można, obok typowych aktów prawa miejscowego stanowionych zgodnie z przepisami Konstytucji, także takie akty, które nie mieszczą się w standardach konstytucyjnych źródeł prawa, choć dotyczą istotnych kwestii społecznych, gospodarczych itp. Tego rodzaju dokumenty (np. akty planowania, programy, strategie itp.), mimo że są uchwalane w drodze uchwał, nie zawsze zawierają przepisy powszechnie obowiązujące. Bez względu jednak na moc wiążącą aktu normatywnego prawodawca powinien przestrzegać powszechnie uznawanych reguł stanowienia prawa, w tym zasady proporcjonalności, racjonalności, komunikatywności i zwięzłości. Przepisy powszechnie obowiązujące często nakładają na samorządy lokalne obowiązek tworzenia aktów regulujących ważne kwestie społeczne, np. program profilaktyki i rozwiązywania problemów alkoholowych dotyczący zagadnienia sposobu postępowania ze zjawiskiem nałogu alkoholowego w warunkach lokalnych. Programy te często opracowywane są z naruszeniem reguł racjonalnego tworzenia prawa, a ponadto oderwane są od lokalnej rzeczywistości, co powoduje, że są one nieskuteczne. Warto zatem rozważyć możliwość innego sposobu reagowania na zjawisko alkoholizmu, nie za pomocą corocznie uchwalanych uchwał. Obowiązek sporządzania programu profilaktyki i rozwiązywania problemów alkoholowych mógłby zostać zastąpiony np. odpowiednimi działaniami organizacyjnymi, edukacyjnymi itp. Prawo nie zawsze jest właściwym sposobem osiągania zakładanych celów. Wymaga to jednak zmian ustawowych

RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors

The YbeB (DUF143) family of uncharacterized proteins is encoded by almost all bacterial and eukaryotic genomes but not archaea. While they have been shown to be associated with ribosomes, their molecular function remains unclear. Here we show that YbeB is a ribosomal silencing factor (RsfA) in the stationary growth phase and during the transition from rich to poor media. A knock-out of the rsfA gene shows two strong phenotypes: (i) the viability of the mutant cells are sharply impaired during stationary phase (as shown by viability competition assays), and (ii) during transition from rich to poor media the mutant cells adapt slowly and show a growth block of more than 10 hours (as shown by growth competition assays). RsfA silences translation by binding to the L14 protein of the large ribosomal subunit and, as a consequence, impairs subunit joining (as shown by molecular modeling, reporter gene analysis, in vitro translation assays, and sucrose gradient analysis). This particular interaction is conserved in all species tested, including Escherichia coli, Treponema pallidum, Streptococcus pneumoniae, Synechocystis PCC 6803, as well as human mitochondria and maize chloroplasts (as demonstrated by yeast two-hybrid tests, pull-downs, and mutagenesis). RsfA is unrelated to the eukaryotic ribosomal anti-association/60S-assembly factor eIF6, which also binds to L14, and is the first such factor in bacteria and organelles. RsfA helps cells to adapt to slow-growth/stationary phase conditions by down-regulating protein synthesis, one of the most energy-consuming processes in both bacterial and eukaryotic cells

The Herschel Exploitation of Local Galaxy Andromeda (HELGA). I: Global far-infrared and sub-mm morphology

We have obtained Herschel images at five wavelengths from 100 to 500 micron of a ~5.5x2.5 degree area centred on the local galaxy M31 (Andromeda), our nearest neighbour spiral galaxy, as part of the Herschel guaranteed time project "HELGA". The main goals of HELGA are to study the characteristics of the extended dust emission, focusing on larger scales than studied in previous observations of Andromeda at an increased spatial resolution, and the obscured star formation. In this paper we present data reduction and Herschel maps, and provide a description of the far-infrared morphology, comparing it with features seen at other wavelengths. We use high--resolution maps of the atomic hydrogen, fully covering our fields, to identify dust emission features that can be associated to M31 with confidence, distinguishing them from emission coming from the foreground Galactic cirrus. Thanks to the very large extension of our maps we detect, for the first time at far-infrared wavelengths, three arc-like structures extending out to ~21, ~26 and ~31 kpc respectively, in the south-western part of M31. The presence of these features, hosting ~2.2e6 Msol of dust, is safely confirmed by their detection in HI maps. Overall, we estimate a total dust mass of ~5.8e7 Msol, about 78% of which is contained in the two main ring-like structures at 10 and 15 kpc, at an average temperature of 16.5 K. We find that the gas-to-dust ratio declines exponentially as a function of the galacto-centric distance, in agreement with the known metallicity gradient, with values ranging from 66 in the nucleus to ~275 in the outermost region. [Abridged]Comment: 15 Pages, 9 Figures. Accepted for publication in Astronomy and Astrophysics. A high resolution version of the paper can be found at http://wazn.ugent.be/jfritz/HelgaI_final.pd

Minding impacting events in a model of stochastic variance

We introduce a generalisation of the well-known ARCH process, widely used for generating uncorrelated stochastic time series with long-term non-Gaussian distributions and long-lasting correlations in the (instantaneous) standard deviation exhibiting a clustering profile. Specifically, inspired by the fact that in a variety of systems impacting events are hardly forgot, we split the process into two different regimes: a first one for regular periods where the average volatility of the fluctuations within a certain period of time is below a certain threshold and another one when the local standard deviation outnumbers it. In the former situation we use standard rules for heteroscedastic processes whereas in the latter case the system starts recalling past values that surpassed the threshold. Our results show that for appropriate parameter values the model is able to provide fat tailed probability density functions and strong persistence of the instantaneous variance characterised by large values of the Hurst exponent is greater than 0.8, which are ubiquitous features in complex systems.Comment: 18 pages, 5 figures, 1 table. To published in PLoS on

Characterization of Microstructure of a Postglacial Deposit Based on in Situ Testing, Laboratory Testing, and Numerical Analysis

publishedVersio

Community Service Learning Packet

This learning packet contains a set of exercises designed to stimulate the student\u27s thinking about their community and the value of community service. It begins with a personal definition of the word community. From this definition, the student then gathers information about the school community. Hopefully, by attending school club meetings students will increase their sense of belonging and learn about options for volunteering at their campus. The notion that young people are selfish and hedonistic is examined in a section about stereotypes and biased news reporting. To break up the worksheet sequence two movie assignment guides are provided, where students view stories of compassion or caring and documentaries about youth performing volunteer service

Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon

The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local land–atmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good