2,243 research outputs found

    Time Series Data Mining: A Retail Application Using SAS Enterprise Miner

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    Modern technologies have allowed for the amassment of data at a rate never encountered before. Organizations are now able to routinely collect and process massive volumes of data. A plethora of regularly collected information can be ordered using an appropriate time interval. The data would thus be developed into a time series. With such data, analytical techniques can be employed to collect information pertaining to historical trends and seasonality. Time series data mining methodology allows users to identify commonalities between sets of time-ordered data. This technique is supported by a variety of algorithms, notably dynamic time warping (DTW). This mathematical technique supports the identification of similarities between numerous time series. The following research aims to provide a practical application of this methodology using SAS Enterprise Miner, an industry-leading software platform for business analytics. Due to the prevalence of time series data in retail settings, a realistic product sales transaction data set was analyzed. This information was provided by dunnhumbyUSA. Interpretations were drawn from output that was generated using “TS nodes” in SAS Enterprise Miner

    P-225: Effective blood-pressure control with valsartan/HCTZ combination therapy in patients with moderate to severe systolic hypertension: The valor trial

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    Increasing evidence shows that combination therapy with at least two antihypertensive agents is needed to achieve appropriate blood-pressure (BP) control in a large part of the hypertensive population. One of the most appealing combinations is that of adding a diuretic to an angiotensin-receptor blocker (ARB). We studied the effects on sitting systolic BP of the combinations valsartan (V; an ARB) 160 mg + HCTZ 12.5 mg and V160 mg + HCTZ 25 mg od, compared with monotherapy V160 mg od. Treatment-naive and previously treated patients (N=767) with moderate to severe systolic hypertension (SBP ≥160 mm Hg and ≤200 mmHg) and with or without co-morbidities, were randomised (after a 2-week washout if previously treated and a 2 week placebo run-in period) to either V80 od (monotherapy group) or V160 od (combination groups) for 4 weeks, with force-tration to V160 mg, V160/HCTZ 12.5 od or V160/HCTZ 25 od for an additional 4 weeks. Endpoints were change in SBP between V160 and V160/HCTZ 25 and between V160/HCTZ 12.5 and V160; changes in DBP between groups, response rates and tolerability. As shown in the Table, all treatments were highly effective and there were additional SBP and DBP reductions in the combination groups. Responder rates were above 50% in all groups and reached 75% in the V160/HCTZ 25 group. Rates of adverse events did not differ significantly between monotherapy and combination therapies. Table 1 V160 V160/HCTZ12.5 V160/HCTZ25 N 261 254 252 Male/female 130/131 141/113 140/112 Mean age 60.4 (10.6) 60.8 (11.5) 60.7 (11.6) Baseline mean SBP/DBP 167.9 (8.0)/93.2 (8.9) 167.4 (8.3)/93.4 (9.6) 167.2 (7.9)/93.7 (8.8) Mean change SBP/DBP −20.7 (15.7)/−6.6 (8.9) −27.9 (13.8) *−10.2 (7.7)* −28.3 (13.1) *−10.1 (7.8)* Response rate¥ 56.9% 74.4% * 75% * Any AE (monotherapy phase/combination phase) 37.3%/27.5% 32.1%/28.6% 32.8%/34.0% Values in brackets are ± SD. *P < 0.05 vs V160; ¥SBP < 140 or decrease in SBP ≥20 mmHg and/or DBP<90 mmHg. V160 mg od is safe and effective in patients with moderate to severe systolic hypertension. Adding HCTZ 12.5 or 25 mg provides significant additional reductions in systolic and diastolic BP and increases responder rates compared with V160 mg monotherapy, with maintained excellent tolerabilit

    Continuous-wave spontaneous lasing in mercury pumped by resonant two-photon absorption

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    The first continuous-wave two-photon absorption laser-induced stimulated emission (CTALISE) is demonstrated. The 7^1S-6^1P transition in mercury at 1014nm wavelength is used and selective lasing of different isotopes is observed.Comment: 3 pages, 5 figure

    Comportamiento de la parasitosis intestinal en niños menores de 15 años que habitan en área urbana del Municipio de Ocotal, Departamento de Nueva Segovia en el año 2015

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    Se realizó un estudio descriptivo, retrospectivo de corte transversal a 117 niños, cuyo principal objetivo fue determinar el comportamiento de las parasitosis intestinal en niños menores de 15 años, que habitan en el área urbana del municipio de Ocotal, departamento de Nueva Segovia en el año 2015. Se identificó un total de 10 especies, de estos 8 fueron Protozoos (amebas, flagelados, Blastocystis hominis, coccidios) y 2 de Helmintos (Hymenolepis, Trichuris) con un porcentaje total de parasitación del 83.8%. En el grupo de los protozoos, Giardia intestinalis fue el de mayor prevalencia (40.2%), seguido por Blastocystis hominis con (35.9%), y Helmintos, fue Hymenolepis nana (2.6%), Al analizar el sexo, las niñas presentaron el mayor porcentaje con el 87%, y si se analiza por cada especie identificada los mayores porcentajes presentados por los niños correspondieron a Entamoeba coli (23.8%), Entamoeba complejo (28.6%) y Giardia intestinalis (42.9%), y en las niñas fueron Entamoeba hartmanni (7.4%), Endolimax (29.6%), Iodamoeba (20.4%), Cyclospora (1.9%), Blastocystis (40.7%), Hymenolepis (3.7%) y Trichuris (1.9%). En relación a la edad se nota que están más parasitados los niños de edad escolar 6 a 8 años (91.7%) y de 9 a 11 años (95.7%). El porcentaje total de multi parasitismos identificados en los niños estudiados fue del 53%, que osciló de 2 a 5 especies diferentes. En conclusión tenemos que se identificó una prevalencia total de 83.8%, encontrándose protozoos de mayor predominio fueron Giardia intestinalis (40.2%), Blastocystis hominis (35.9%), Endolimax nana (27.4%). Marcado predominio de los protozoos 83.8% en relación a los helmintos 3.4%. Se demostró que el sexo femenino presentó mayor prevalencia de parasitación total con el 87%, encontrándose 8 especies, 3 patógenos y Blastocystis hominis, siendo la edad más afectada fue la escolar de 9 a 11 años con 95.7%. En lo relacionado al multi parasitismos total es de alta prevalencia con el 53%, con mayor frecuencia la presencia de dos especies parasitarias con el 22.2%, estos porcentajes altos se explican por la existencia de condiciones higiénico sanitaria precaria; la ausencia de alcantarillado (70.1%), y la presencia de vectores como son las moscas con el 66.7% y mamíferos con 76.1%

    Electrochemical Pitting And Repassivation On Icosahedral AL-CU-FE, And A Comparison With Crystalline Phases

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    We report the electrochemical potentials at which localized pitting and repassivation occur on icosahedral Al-Cu-Fe, and on a series of related alloys and elemental metals. The electrochemistry occurs in a buffered NaCI solution, pH 8.4. Under these conditions, pitting and repassivation appear to be controlled mainly by the chemical composition of the alloy, although the quasicrystalline phase displays an anomalous resistance to repassivation. Corrosion of this phase proceeds by dissolution of Al and Fe, leaving behind pits which are Cu-enriched

    High capacity digital beam steering technology

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    A novel method is described in detail for steering light in many directions without moving mechanical parts. The method involves a combination of liquid crystal cells and polarizing beam splitters. The polarization at each beam splitter is controlled by applying a signal to its corresponding liquid crystal cell. A study of light steering techniques is described for efficient beam placement, in a line and plane. These techniques permit accurate, non-mechanical, beam steering limited by the response time of the liquid crystal cells. A theoretical limit to the number of discrete directions is described and closely approached for a one dimensional system

    The Industrial Village Energy Approach: A Cost-Effective Approach To Balance Interests and Collaboratively Harness Onsite Solar Energy

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    While the residential sector has seen a strong and rapid uptake of photovoltaic panels on rooftops in the last decade, especially in Australia, the uptake has been much slower on commercial and industrial roofs. This research focuses on how commercial and industrial precincts can transition to cost-effective long-term solar energy generation in a manner that creates multiple benefits. The outcome is a new approach that benefits the energy customers, the embedded utility and the environment
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