Static aerodynamic characteristics of a 0.035-scale model of a modified NKC-135 airplane at a Mach number of 0.28

A 0.035-scale model fo a modified NKC-135 airplane was tested in 12-foot pressure wind tunnel to determine the effects on the static aerodynamic characteristics of modifications to the basic aircraft. Modifications investigated included: nose, lower fuselage, and upper fuselage radomes; wing pylons and pods; overwing probe; and air conditioning inlets. The investigation was performed at a Mach number of 0.28 over a Reynolds number range from 6.6 to 26.2 million per meter. Angles of attack and sideslip varied from -8 deg to 20 deg and from -18 deg to 8 deg, respectively, for various combinations of flap, aileron, and rudder deflections. A limited analysis of the test results indicates that the addition of the radomes reduces lateral-directional stability and control effectiveness of the basic aircraft

Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation

Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area. Research projects in this area tend to be small and driven by particular institutional problems or concerns. As a consequence, proposed solutions from experimental projects and prototypes tend not to scale to millions of digital objects, nor do the results from disparate projects readily build on each other. It is also unclear whether it is worthwhile to seek general solutions or whether different strategies are needed for different types of digital objects and collections. The lack of coordination in both research and development means that there are some areas where researchers are reinventing the wheel while other areas are neglected. Digital archiving and preservation is an area that will benefit from an exercise in analysis, priority setting, and planning for future research. The WG aims to survey current research activities, identify gaps, and develop a white paper proposing future research directions in the area of digital preservation. Some of the potential areas for research include repository architectures and inter-operability among digital archives; automated tools for capture, ingest, and normalization of digital objects; and harmonization of preservation formats and metadata. There can also be opportunities for development of commercial products in the areas of mass storage systems, repositories and repository management systems, and data management software and tools.

Estimates in Beurling--Helson type theorems. Multidimensional case

We consider the spaces $A_p(\mathbb T^m)$ of functions $f$ on the $m$ -dimensional torus $\mathbb T^m$ such that the sequence of the Fourier coefficients $\hat{f}=\{\hat{f}(k), ~k \in \mathbb Z^m\}$ belongs to $l^p(\mathbb Z^m), ~1\leq p<2$. The norm on $A_p(\mathbb T^m)$ is defined by $\|f\|_{A_p(\mathbb T^m)}=\|\hat{f}\|_{l^p(\mathbb Z^m)}$. We study the rate of growth of the norms $\|e^{i\lambda\varphi}\|_{A_p(\mathbb T^m)}$ as $|\lambda|\rightarrow \infty, ~\lambda\in\mathbb R,$ for $C^1$ -smooth real functions $\varphi$ on $\mathbb T^m$ (the one-dimensional case was investigated by the author earlier). The lower estimates that we obtain have direct analogues for the spaces $A_p(\mathbb R^m)$

Absorbing boundary conditions for the Westervelt equation

The focus of this work is on the construction of a family of nonlinear absorbing boundary conditions for the Westervelt equation in one and two space dimensions. The principal ingredient used in the design of such conditions is pseudo-differential calculus. This approach enables to develop high order boundary conditions in a consistent way which are typically more accurate than their low order analogs. Under the hypothesis of small initial data, we establish local well-posedness for the Westervelt equation with the absorbing boundary conditions. The performed numerical experiments illustrate the efficiency of the proposed boundary conditions for different regimes of wave propagation

Atmospheric conditions and their effect on ball-milled magnesium diboride

Magnesium diboride bulk pellets were fabricated from pre-reacted MgB2 powder ball milled with different amounts of exposure to air. Evidence of increased electron scattering including increased resistivity, depressed Tc, and enhanced Hc2 of the milled and heat treated samples were observed as a result of increased contact with air. These and other data were consistent with alloying with carbon as a result of exposure to air. A less clear trend of decreased connectivity associated with air exposure was also observed. In making the case that exposure to air should be considered a doping process, these results may explain the wide varibability of "undoped" MgB2 properties extant in the literature.Comment: Work presented at ASC 2006 in Seattl

Maternal neurofascin-specific autoantibodies bind to structures of the fetal nervous system during pregnancy, but have no long term effect on development in the rat

Neurofascin was recently reported as a target for axopathic autoantibodies in patients with multiple sclerosis (MS), a response that will exacerbate axonal pathology and disease severity in an animal model of multiple sclerosis. As transplacental transfer of maternal autoantibodies can permanently damage the developing nervous system we investigated whether intrauterine exposure to this neurofascin-specific response had any detrimental effect on white matter tract development. To address this question we intravenously injected pregnant rats with either a pathogenic anti-neurofascin monoclonal antibody or an appropriate isotype control on days 15 and 18 of pregnancy, respectively, to mimic the physiological concentration of maternal antibodies in the circulation of the fetus towards the end of pregnancy. Pups were monitored daily with respect to litter size, birth weight, growth and motor development. Histological studies were performed on E20 embryos and pups sacrificed on days 2, 10, 21, 32 and 45 days post partum. Results: Immunohistochemistry for light and confocal microscopy confirmed passively transferred anti-neurofascin antibody had crossed the placenta to bind to distinct structures in the developing cortex and cerebellum. However, this did not result in any significant differences in litter size, birth weight, or general physical development between litters from control mothers or those treated with the neurofascin-specific antibody. Histological analysis also failed to identify any neuronal or white matter tract abnormalities induced by the neurofascin-specific antibody. Conclusions: We show that transplacental transfer of circulating anti-neurofascin antibodies can occur and targets specific structures in the CNS of the developing fetus. However, this did not result in any pre- or post-natal abnormalities in the offspring of the treated mothers. These results assure that even if anti-neurofascin responses are detected in pregnant women with multiple sclerosis these are unlikely to have a negative effect on their children

Positive youth development in swimming: clarification and consensus of key psychosocial assets

The purpose of this study was to gain a more cohesive understanding of the assets considered necessary to develop in young swimmers to ensure both individual and sport specific development. This two stage study involved (a) a content analysis of key papers to develop a list of both psychosocial skills for performance enhancement and assets associated with positive youth development, and (b) in-depth interviews involving ten expert swim coaches, practitioners and youth sport scholars. Five higher order categories containing seventeen individual assets emerged. These results are discussed in relation to both existing models of positive youth development and implications for coaches, practitioners and parents when considering the psychosocial development of young British swimmers

The Status of Licensed Professional Counselors in Michigan Public Universities

This article documents the findings of a study investigating the employment status of licensed professional counselors in Michigan’s 15 public universities. Structured interviews were conducted by telephone with 85 professionals working in college counseling centers, career centers, advising, admissions, financial aid, and residence life offices. The results indicated that only a very small percentage of employees in these offices are licensed as professional counselors, and a substantial number have not received training in counseling

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Systematic Review of Preclinical Surgical Meshes for Hernia Repair

Hernia repair is one of the most common procedures performed around the world. Surgical mesh materials are used to reinforce hernia repairs and improve surgical outcomes. However, current commercial mesh materials produce problems such as infection, rejection, shrinkage, adhesion, and mechanical failure. These problems contribute to a high rate of hernia recurrence and mesh removal. With the number of hernias expected to rise in the future due to increases in obesity and diabetes, the need for more effective mesh materials is critical. This review aims to identify, evaluate, and summarize experimental surgical mesh materials used in the preclinical stages of development and catalogue their characteristics and the tests used for their evaluation.https://digitalcommons.unmc.edu/surp2021/1053/thumbnail.jp