A Grounded Theory of Suicidality in Children Ten and Younger

Once every two days in the United States, a child aged 5 to 14 years old dies by suicide (World Health Organization, 2010). When viewed on a spectrum that includes suicidal ideation, verbalizations, behaviors, and attempts, the problem of youth suicidality is actually far greater than the numbers of completed suicides suggest (Cheng, Tao, Riley, Kann, Ye, Tian...Hu, 2009). This study examined suicidality in children ages 10 and younger, and included the characteristics of suicidal children, factors that influence childhood suicidality, and treatment implications. The researcher conducted 12 semi-structured qualitative interviews with experienced treatment providers and performed a content analysis on 22 treatment charts of children identified as being suicidal in order to construct a grounded theory on childhood suicidality. This study found a core category of childhood suicidality, which resulted in 4 axial codes related to the spectrum suicidality present in children 10 and younger, including: suicidal ideation, verbalization, behaviors, and attempts. Through 21 open and 6 focused codes, it was also shown that suicidal children present with a range of behavioral and emotional disruption. A total of 6 axial codes interpreted causal conditions of childhood suicidality, including: abuse & neglect, separation from a primary caregiver, other trauma & stressors, negative familial influences, mental illness, and physical illness. Treatment implications were also found, and included 1 axial code of psychiatric interventions, as well as a researcher-developed theoretical code the primary researcher has labeled The RESCUE Model for Childhood Suicidality, which provides a framework for treatment that teachers, counselors, parents and other caregivers can use when they encounter suicidal children 10 and younger. Finally, barriers to the effective treatment of childhood suicidality were also discussed as a mediating factor to the success of treatment interventions

Top Management Team Competencies - A Study of an International Acquisition by a Medium-Sized, Swedish Engineering Company

The aim of this thesis is to create a competency model that is applicable to the top management team (TMT) of a medium-sized, Swedish engineering company before and during a company expansion to countries in which it does not already have operations in. Using theory and empirical data from interviews, a comparison is made in order to present a Final Competency Model in the end. In the first chapter, the Theoretical Framework that is, theory on numerous topics relevant to internationalization in general is presented and discussed, before it is concluded and a presentation of the identified competencies is made. The next chapter, containing empirical data from three interviews, presents arguments that supports and/or contradicts each of the identified competencies. It further presents three additional competencies that were derived solely based on the three interviews and therefore is specific to the case. In conclusion, ten competencies were identified whose importance is argued for in many of the sections of this thesis. The competencies that are not possessed by the TMT, or the teams responsible for the company’s expansion project, in this case an expansion into Norway, appear to be acquired through external consultants or recruitment. In order to achieve the desired synergies the case company uses detailed checklists and processes while a person with a very strong internal network is responsible for the integration project. Additionally, the empirical data indicates a focus towards the organizational culture, rather than the national culture, when the case company analyzed and prepared for the acquisition and integration of the Norwegian company

Synthesis and Characterization of New Azido Esters Derived from Malonic Acid

Three new α,α‐diazidated azido esters derived from malonic acid were synthesized and characterized with a method of diazidation under mild reaction conditions. They are energy‐rich, small, liquid molecules which contain up to six azido moieties. The three synthesized compounds were compared to already known azidated malonic acid esters regarding their density, thermal stability, calculated heat of formation and energetic properties. Further they were tested and classified for their sensitivities according to UN guidelines

El turismo como actividad productiva en los puertos, los puertos como atractivos turísticos. Nuevas miradas sobre el puerto de la ciudad de Mar del Plata

El presente trabajo busca compartir la experiencia llevada a cabo por estudiantes y docentes de la carrera Licenciatura en Turismo de la Facultad de Ciencias Económicas y Sociales (FCEyS) de la Universidad Nacional de Mar del Plata (UNMdP) en la zona puerto de la ciudad de Mar del Plata, Buenos Aires, Argentina durante el año 2020. El proyecto que se presenta surge a partir de una iniciativa de la Secretaría de Vinculación con el Medio de esta Unidad Académica y contó con el acompañamiento de la delegación de Coordinación Turística de la Subsecretaría de Turismo de la Provincia de Buenos Aires y el asesoramiento del Consorcio Portuario Regional de la ciudad. Mar del Plata se constituye como primer destino doméstico de Argentina, su promedio de visitas anuales (previo a la irrupción del COVID-19) superaba los 8 millones de personas (Ente Municipal de Turismo, Municipalidad de General Pueyrredon, 2019). Dentro de los circuitos turísticos de la ciudad, la zona puerto es de las más convocantes para turistas y residentes. En este espacio se desarrollan diversas actividades pesqueras, industriales, comerciales, de servicios y turístico-recreativas que se complementan, transformando el entorno en un atractivo turístico. El proyecto que se describe tuvo como foco la obtención de nuevas miradas sobre la zona con la propuesta de circuitos turísticos innovadores que consideran a la actividad turística desde el punto de vista productivo y complementario en los puertos y, a la vez, a estos puertos como atractivos turísticos en sí mismos. Los ejes transversales de esta nueva propuesta también buscaban incorporar aspectos claves de la innovación, la incorporación de tecnología a la experiencia, la sustentabilidad, y la accesibilidad en términos de igualdad.Fil: Mertens, Violeta. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Veltri, Romina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Heimsch, Anna Madelein. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Riquert, Astrid. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina

Turismo y espacio público: percepciones de los actores comunitarios en destinos costeros. El caso de la "Asamblea por los Espacios Públicos" en el Partido de Gral. Pueyrredon (Argentina)

Mar del Plata es reconocida como uno de los principales destinos turísticos del país, siendo la playa uno de los atractivos más elegidos por una gran cantidad de argentinos que disfrutan de su verano en la ciudad. El proceso de urbanización que trajo consigo el crecimiento del movimiento turístico, dio lugar a una serie de transformaciones en la configuración de los espacios públicos. En este sentido, desde inicios del siglo XX ciertos agentes turísticos comenzaron a apreciar la franja costera como un factor productivo para la explotación turística, la cual se daría a partir de la privatización de las playas (Castellucci, 2022; Cicalese, 2002; Cruz, 2020). Dicha acción generó conflicto con distintos actores locales, tales como los residentes, los cuales se agruparon en organizaciones para defender la utilización y disfrute de sus espacios (Cicalese, 2002; Cruz, 2020). En este contexto, el presente trabajo tiene como objetivo estudiar la percepción de los miembros de la "Asamblea por los Espacios Públicos" respecto del desarrollo del turismo en el espacio costero sur del Partido de General Pueyrredon.Fil: Heimsch, Anna Madelein. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Castellucci, Daniela I. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Cruz, Gonzalo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina

Effects of a tree row on greenhouse gas fluxes, growing conditions and soil microbial communities on an oat field in Southern Finland

Agricultural ecosystems are facing critical loss of biodiversity, soil nutrients, and cultural values. Intensive crop production has caused landscape homogenisation, with trees and hedges increasingly disappearing from agricultural land. Changes in farming practices are essential to increase biodiversity and improve soil biogeochemical processes, such as nutrient cycling, soil carbon uptake, and sequestration, as well as to improve the resilience and fertility of farming systems. Agroforestry is an important practice for implementing and improving natural and cultural value of landscapes, but in northern countries, agroforestry methods remain rarely utilised. Our study was conducted in Southern Finland on an agricultural field where a row of willow and alder was planted 6 years prior to our study. We concentrated on the effects of the tree row on crop growing conditions and how far from the trees possible impacts can be observed. We studied soil properties, carbon dioxide (CO2), nitrous oxide (N2O), and methane (CH4) exchange, and soil microbial communities. The impact of trees on crop growing conditions, biomass production, and greenhouse gas fluxes was modest and did not extend further than few meters from the tree row in the warm and dry growing season of 2019. N2O and CH4 fluxes were negligible and the tree row did not increase greenhouse gas emissions from soil. Soil microbial diversity was clearly improved by the presence of trees due to more diverse habitats. The tree row also slightly decreased the estimated annual net emissions of carbon into the atmosphere. Due to positive indications of the effects of agroforestry on biodiversity and carbon uptake, we highly recommend further studies within various agroforestry practices in Nordic countries

Carbon dioxide fluxes and carbon balance of an agricultural grassland in southern Finland

A significant proportion of the global carbon emissions to the atmosphere originate from agriculture. Therefore, continuous long-term monitoring of CO2 fluxes is essential to understand the carbon dynamics and balances of different agricultural sites. Here we present results from a new eddy covariance flux measurement site located in southern Finland. We measured CO2 and H2O fluxes at this agricultural grassland site for 2 years, from May 2018 to May 2020. In particular the first summer experienced prolonged dry periods, which affected the CO2 fluxes, and substantially larger fluxes were observed in the second summer. During the dry summer, leaf area index (LAI) was notably lower than in the second summer. Water use efficiency increased with LAI in a similar manner in both years, but photosynthetic capacity per leaf area was lower during the dry summer. The annual carbon balance was calculated based on the CO2 fluxes and management measures, which included input of carbon as organic fertilizers and output as yield. The carbon balance of the field was -57 +/- 10 and -86 +/- 12 g C m(-2) yr(-1) in the first and second study years, respectively.Peer reviewe

Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium Falciparum Infected Red Blood Cells

Plasmodium falciparum causes the most lethal form of malaria. Peroxide antimalarials based on artemisinin underpin the frontline treatments for malaria, but artemisinin resistance is rapidly spreading. Synthetic peroxide antimalarials, known as ozonides, are in clinical development and offer a potential alternative. Here, we used chemoproteomics to investigate the protein alkylation targets of artemisinin and ozonide probes, including an analogue of the ozonide clinical candidate, artefenomel. We greatly expanded the list of proteins alkylated by peroxide antimalarials and identified significant enrichment of redox-related proteins for both artemisinins and ozonides. Disrupted redox homeostasis was confirmed by dynamic live imaging of the glutathione redox potential using a genetically encoded redox-sensitive fluorescence-based biosensor. Targeted liquid chromatography-mass spectrometry (LC-MS)-based thiol metabolomics also confirmed changes in cellular thiol levels. This work shows that peroxide antimalarials disproportionately alkylate proteins involved in redox homeostasis and that disrupted redox processes are involved in the mechanism of action of these important antimalarials