Венчурні інвестиції: сутність, форми, контрагенти

У статті досліджено генезис категорії "венчурні інвестиції", еволюцію форм організації венчурних інвестицій, конкретизовано специфіку інвесторів і реципієнтів венчурного капіталу

Effect of pediatric physical therapy on deformational plagiocephaly in children with positional preference: a randomized controlled trial

Objective To study the effect of pediatric physical therapy on positional preference and deformational plagiocephaly.\ud \ud Design Randomized controlled trial.\ud \ud Setting Bernhoven Hospital, Veghel, the Netherlands.\ud \ud Participants Of 380 infants referred to the examiners at age 7 weeks, 68 (17.9%) met criteria for positional preference, and 65 (17.1%) were enrolled and followed up at ages 6 and 12 months.\ud \ud Intervention Infants with positional preference were randomly assigned to receive either physical therapy (n = 33) or usual care (n = 32).\ud \ud Main Outcome Measures The primary outcome was severe deformational plagiocephaly assessed by plagiocephalometry. The secondary outcomes were positional preference, motor development, and cervical passive range of motion.\ud \ud Results Both groups were comparable at baseline. In the intervention group, the risk for severe deformational plagiocephaly was reduced by 46% at age 6 months (relative risk, 0.54; 95% confidence interval, 0.30-0.98) and 57% at age 12 months (0.43; 0.22-0.85). The numbers of infants with positional preference needed to treat were 3.85 and 3.13 at ages 6 and 12 months, respectively. No infant demonstrated positional preference at follow-up. Motor development was not significantly different between the intervention and usual care groups. Cervical passive range of motion was within the normal range at baseline and at follow-up. When infants were aged 6 months, parents in the intervention group demonstrated significantly more symmetry and less left orientation in nursing, positioning, and handling.\ud \ud Conclusion A 4-month standardized pediatric physical therapy program to treat positional preference significantly reduced the prevalence of severe deformational plagiocephaly compared with usual care

Real-Time System Implementation on Autonomous Lego-Robot

A new hardware abstraction layer was created for the EV3. This includes drivers for UART, timers, interrupt controller, SPI and I2C peripherals. This was documented using Doxygen; an in-code documenting tool. Doxygen was used to create an off-line reference manual for the abstraction layer as a PDF (generated with LaTeX). Using the new drivers for the timer and interrupt controller, FreeRTOS was implemented on the EV3 using the timer interrupt as an RTOS tick interrupt for the FreeRTOS scheduler. A new port file for the RTOS was created that is compatible with the Texas Instruments AM1808 MCU in the EV3, and Doxygen was then configured to extract the FreeRTOS code structure such that the RTOS layer interface documentation was added to the reference manual. The robot was built using a previously built AVR-based robot as a reference. EV3 Large Servo Motors were used for wheel movement and to control the sensor tower. Given the remaining sensor ports on the EV3 only fits four sensors and there is no access to the GPIO pins in the AM1808 in the EV3 directly, there is not enough room for the remaining sensors to be implemented on the robot without an additional hardware card to interface with the sensors. The sensors needed for the SLAM application are four IR sensors, one gyro, one electronic compass and a BLE dongle. Plans were made to use a card developed for a similar problem on a Lego NXT robot, but due to time constraints, the card was not produced in this thesis. Finally, the application was ported to the EV3 and with FreeRTOS running almost no changes to the code was needed to get implemented, only a few minor EV3 specific hardware calls to the motors needed to be changed

Exercise training in pediatric patients with end-stage renal disease

The objective of this study was to determine the feasibility and efficacy of an exercise training program to improve exercise capacity and fatigue level in pediatric patients with end-stage renal disease (ESRD). Twenty children on dialysis intended to perform a 12-week graded community-based exercise program. Exercise capacity and fatigue level were studied; muscle force and health-related quality of life were secondary outcomes. All outcomes were measured at baseline (T = 0) and after intervention (T = 1). Fourteen of the 20 patients (70%) either did not start the program or did not complete the program. Of these patients, seven did not complete or even start the exercise program because of a combination of lack of time and motivational problems. Six patients were not able to continue the program or were unable to do the follow-up measurements because of medical problems. Exercise capacity and muscle strength was higher after the exercise program in the children who completed the training. In conclusion, exercise training is difficult to perform in children with ESRD and is not always feasible in real-life situations for many children with ESRD

Effects of temperature on amoebic gill disease development : Does it play a role?

Funding Information Scottish Government project grant. Grant Number: AQ0080 University of Aberdeen Marine Scotland Science (MSS) Marine Laboratory, UKPeer reviewedPostprintPostprin

Forebygge utvikling av skadelig seksuell atferd hos barn og unge

Innledning: Helsedirektoratet omtaler skadelig seksuell atferd [SSA] mot barn og unge som en av de største utfordringene i folkehelsearbeidet nå og i tiden fremover. Barn og unge står for rundt 30-50 prosent av overgrep mot barn og unge, og det er trolig store mørketall. Barn og unges utvikling kan påvirkes av ulike faktorer i hverdagen. SSA mot barn og unge kan medføre alvorlige psykiske og fysiske konsekvenser. Oppgavens hensikt er å undersøke hva forskning sier om forebyggende tiltak rettet mot utvikling av SSA hos barn og unge. Metode: En litteraturstudie med systematisk litteratursøk i databaser. Resultat: En oversiktsartikkel, en kvalitativ forskningsartikkel og en kvantitativ forskningsartikkel ble inkludert. Tre faktorer for å forebygge utvikling av SSA hos barn og unge ble identifisert: bedre seksualundervisning, barns kunnskap og kompetanse til kritisk vurdering av pornografisk innhold, og undervisning av foreldre og skoleansatte. Barn og unge har behov for seksualundervisning før fylte 6 og 12 års alder. Rollespill og aktiv deltakelse i undervisningen har vist positiv effekt på kunnskapsutbyttet av seksualundervisning. Eksponering for pornografi og kritisk vurdering av pornografisk innhold må adresseres i seksualundervisning. Rollemodeller som foreldre og skoleansatte er viktige informasjonskilder for barn og unge, og deres kunnskap om SSA er av stor betydning for å forebygge utvikling av skadelig seksuell atferd. Konklusjon: Litteraturgjennomgangen identifiserte tre faktorer som kan forebygge utvikling av SSA hos barn og unge; tidligere og bedre seksualundervisning, barns kompetanse om kritiske vurdering av pornografisk innhold, og kunnskapen om SSA hos foreldre og skoleansatte. Helsesykepleier er i en unik posisjon til å forebygge utvikling av SSA med sin sentrale rolle i helsestasjon og skolehelsetjenesten. Tiltakene i denne litteraturgjennomgangen styrker forebyggingsagendaen til helsesykepleier, herunder forebygge utvikling av skadelig seksuell atferd hos barn og unge

Prolonged exercise testing in two children with a mild Multiple Acyl-CoA-Dehydrogenase deficiency

BACKGROUND: Multiple Acyl-CoA-Dehydrogenase deficiency (MADD) is an inherited metabolic disorder characterized by impaired oxidation of fatty acids and some amino acids. METHODS: We were interested whether children with MADD could tolerate a prolonged low-intensity exercise test and if this test could have any additional diagnostic value. Therefore, we performed a maximal exercise test and a low-intensity prolonged exercise test in 2 patients with MADD and in 5 control subjects. During a prolonged exercise test the subjects exercised on a cycle ergometer at a constant workload of 30% of their maximum for 90 minutes and heart rate, oxygen uptake, fuel utilization and changes in relevant blood and urinary parameters were monitored. RESULTS: The tests were tolerated well. During the prolonged exercise test the fatty acid oxidation (FAO) was quite low compared to 5 control subjects, while characteristic metabolites of MADD appeared in plasma and urine. CONCLUSION: We suggest that the prolonged exercise test could be of diagnostic importance and might replace the fasting test as a diagnostic procedure in some cases, particularly in patients with anamnestic signs of intolerance for prolonged exercise