Who Are the Givers? Briefing Paper on British Social Attitudes to Charitable Giving

This Institute for Philanthropy paper summarizes the findings of the annual British Social Attitudes Survey on the attitudes and values of Britons regarding charitable giving and philanthropy, and on their behavior. The authors differentiate the target group by age, education, religion, income, political affiliation, and newspaper readership, and determines that there are broadly three groups in British society: contributors, bystanders, and investors

Critical heritage studies, cultural heritage and the current political context in the UK: supporting critical practice?

This paper was conceived of as a brief and fairly straightforward survey of some of the current, imminent and potential shifts in policy and personnel, which might shape ‘heritage practice’ and which might become the basis for further analysis within critical heritage studies. It proposed a brief survey of the Culture White Paper and of the broad focus – if focus isn’t too flattering a term – of current government policy; the actual and potential implications of changes in governance in a number of heritage organisations, from the splitting up of English Heritage to the move to trust status by many local authority museums, and the inevitable impact of reductions in public funding. Instead, it was shaped by the events of late June and early July 2016: the EU Referendum, the 100th anniversary of the battle of the Somme, games of football, Chilcot, and the Museum of the Year Award

Ulnar variance and load transfer in the forearm during maximal grip: a finite element study

The aim of the study was to simulate the effects, ulnar variance has on the load distribution to the radius and ulna during maximal gripping and compare to previously published measurements, which used load cells placed on the forearm bones to measure the load ratio

A three-dimensional finite element model of maximal grip loading in the human wrist

The aim of this work was to create an anatomically accurate three-dimensional finite element model of the wrist, applying subject-specific loading and quantifying the internal load transfer through the joint during maximal grip. For three subjects, representing the anatomical variation at the wrist, loading on each digit was measured during a maximal grip strength test with simultaneous motion capture. The internal metacarpophalangeal joint load was calculated using a biomechanical model. High-resolution magnetic resonance scans were acquired to quantify bone geometry. Finite element analysis was performed, with ligaments and tendons added, to calculate the internal load distribution. It was found that for the maximal grip the thumb carried the highest load, an average of 72.2 ¡ 20.1 N in the neutral position. Results from the finite element model suggested that the highest regions of stress were located at the radial aspect of the carpus. Most of the load was transmitted through the radius, 87.5 per cent, as opposed to 12.5 per cent through the ulna with the wrist in a neutral position. A fully three-dimensional finite element analysis of the wrist using subject-specific anatomy and loading conditions was performed. The study emphasizes the importance of modelling a large ensemble of subjects in order to capture the spectrum of the load transfer through the wrist due to anatomical variation

Beware the painful nerve palsy; neurostenalgia, a diagnosis not to be missed

We present a case of painful radial nerve palsy following application of a humeral lengthening frame. At re-operation, the radial nerve was found to be compressed against a distal pin. This was re-sited providing immediate pain relief and a gradual resolution of the radial nerve palsy. Pain in association with a nerve palsy should alert the clinician to the possibility of nerve compression that may benefit from urgent decompression

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins

In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for the detection of polyether toxins (prymnesins) associated with harmful algal blooms. The added-value of the CuAAC-based approach is evident from our ability to detect novel prymnesin-like compounds in algal species with previously uncharacterised toxins

The determination of traces of inorganic anions by kinetochromic spectrophotometry

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Questionnaire tools for the diagnosis of carpal tunnel syndrome from the patient history

Introduction: There remains no “gold standard” for the diagnosis of carpal tunnel syndrome (CTS). Clinical diagnosis is often held to be paramount but depends on the skills of the individual practitioner. We describe two mathematical approaches to the analysis of a history obtained by questionnaire. Methods: We used two earlier instruments, a conventional logistic regression analysis, and an artificial neural network to analyze data from 5860 patients referred for diagnosis of hand symptoms. We evaluated their ability to predict whether nerve conduction studies would show evidence of CTS using receiver operating characteristic curves. Results: Both new instruments outperformed the existing tools, achieving sensitivity of 88% and specificity of 50% in predicting abnormal median nerve conduction. When combined, 96% sensitivity and 50% specificity were achieved. Conclusion: The combined instrument can be used as a preliminary screening tool for CTS, for self-diagnosis, and as a supplement to diagnosis in primary care