410 research outputs found

    A summary of operations and practice at Shenandoah-Dives

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    The property of the Shenandoah-Dives Mining Company is located in the Animas Mining District, San Juan County, Colorado. The Mine is located on King Solomon Mountain, four miles east and one mile south of Silverton. Silverton is on a branch line of the narrow guage Denver & Rio Grande Western Railway, on which the nearest smelter is located at Durango, a distance of about fifty miles. Included in this report is a claim map showing all the claims and their relative locations --Location of the Property, page 1

    The Impact of the Michigan Gaming Act on Political Contributions

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    Article published in the Michigan State University School of Law Student Scholarship Collection

    Beneath and Beyond the Surfaces: The Road to A Wild Old Man on The Road

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    The psychological themes of innocence, guilt, and betrayal are central to much of Morley Callaghan's works. As Patricia Morley indicates in her article, "Innocence Betrayal and Betraying," there is a significant difference in the treatment of innocence between Callaghan's novels of the thirties and his postwar work. Using the psychoanalytic model of criticism, this thematic development is examined from Callaghan's thirties period to his last novel, A Wild Old Man on the Road (1988). Having established the psychodynamics within both representative novels from several phases in Callaghan's career, as well as the evolving pattern throughout, this analysis reveals a significant correlation between the psychological conflicts within each novel and period, and as they evolve thematically, the various dynamic points within the Oedipus Complex, as described by Sigmund Freud. Callaghan's protagonists feature an inherent Oedipal fixation: they attempt, to varying degrees, yet are unable to attain, Oedipal resolution.Master of Arts (MA

    Advanced Manufacturing of Microengineered Ionic Polymer Metal Composites for Enhanced Sensing Capabilities

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    Ionic Polymer Metal Composites (IPMCs) are ionic electroactive polymers thatexhibit active and passive actuation, sensing, and energy harvesting capabilities. The composite is comprised of an ionic exchange membrane that is sandwiched between two noble metal electrodes and infused with a polar solvent. IPMCs have been primarily studied for their potential as artificial muscles and biomimetic soft robotic actuators, while IPMC sensors have been relatively less examined. In sensing applications, applied mechanical deformation initiates a redistribution of charge within the material, which produces measurable electrical output. In this thesis, two advanced additive manufacturing-based approaches for the fabrication of engineered Ionic Polymer Metal Composite (eIPMC) sensors are investigated. The development of an engineered polymer-metal electrode interface with 3D inkjet-printed and stencil-printed microfeatures is examined for the creation of eIPMC compression sensors with enhanced sensing capabilities.The first chapter provides a thorough review of the background of IPMC sensortechnology and the connection between the material’s structure, fabrication, and sensing performance. IPMC compression sensing is discussed by examining two common theories used to describe the materials underlying compression sensing mechanism. Next, the conventional and advanced manufacturing methods are reviewed to illuminate the motivation of this current work. It is proposed that advancements in manufacturing techniques can ultimately address the current limitations of IPMC sensor application and guide future modeling and research endeavors. IPMC sensor applications and challenges are also thoroughly explored.The second chapter presents two novel approaches for the creation of eIPMCsensors via two additive manufacturing methods: (1) inkjet-printing and (2) stencil-printing. In this work, we tailor the morphology of the polymer-electrode interface with additively manufactured polymer microfeatures to produce inhomogeneous strain upon application of external compression. The goal is to improve the material’s multiphysics sensing properties and produce engineered IPMC (eIPMC) strain sensors with superior sensing performance. Experiments were conducted to compare the sensing behavior between standard (control) IPMC sensors fabricated from commercially available Nafion polymer sheet stock and eIPMC compression sensors. It was found that eIPMC sensors generally outperformed standard IPMC sensors

    Computational Neuroscience: Finding patterns in cortical responses

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    Simulations predict a paradoxical effect that should be revealed by patterned stimulation of the cortex

    The 8th annual computational and systems neuroscience (Cosyne) meeting

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    1 Department of Neurobiology, Harvard Medical School, Boston, USA -- 2 Departments of Psychology and Neurobiology, Center for Perceptual Systems, The University of Texas at Austin, Austin USAThe 8th annual Computational and Systems Neuroscience meeting (Cosyne) was held February 24-27, 2011 in Salt Lake City, Utah (abstracts are freely available online: http://www.cosyne.org/c/index.php?title=Cosyne2011_Program webcite). Cosyne brings together experimental and theoretical approaches to systems neuroscience, with the goal of understanding neurons, neural assemblies, and the perceptual, cognitive and behavioral functions they mediate. The range of questions available to systems and computational neuroscience has grown substantially in recent years, with both theoretical and experimental approaches driven by the increasing availability of data about neural circuits and systems. The Cosyne meeting has reflected this growth, nearly doubling in size since the first meeting in 2004, to a new record of nearly 600 attendees this year. It remains single-track, which allows discussions of presentations to drive scientific interaction between attendees with diverse backgrounds. Poster sessions take place each evening, which provide a forum for intense scientific conversations that frequently spill out into more informal settings late at night. The meeting is followed by two days of workshops, held at the Snowbird ski resort, which feature more specialized talks and interactive discussions on a wide collection of topics, this year ranging from consciousness and compressed sensing to dynamics, learning, and [email protected]

    Amartya Sen, ethics, and economics in the health care sector.

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    Economics promotes market mechanisms for the efficient use of resources in satisfying human want, yet market mechanisms are apparently unable to provide adequate health care and thereby satisfy a need central to a person’s well-being. This research report looks at the views of Amartya Sen and particularly his ideas of distributive justice and capability. It also considers some of the insights that economics provides for an understanding of the apparent limitations that occur in health care provision. The findings point towards a curtailed view of what may reasonably be obtained and a recognition that only limited agreement on any arrangement for health care provision may be possible within society. Sen’s capability approach provides a pertinent and expansive measure of a person’s well-being and freedom; it should not be ignored in any evaluation of well-being or the acceptability of any policy purporting to improve well-being

    Microstimulation of Frontal Cortex Can Reorder a Remembered Spatial Sequence

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    Complex goal-directed behaviors extend over time and thus depend on the ability to serially order memories and assemble compound, temporally coordinated movements. Theories of sequential processing range from simple associative chaining to hierarchical models in which order is encoded explicitly and separately from sequence components. To examine how short-term memory and planning for sequences might be coded, we used microstimulation to perturb neural activity in the supplementary eye field (SEF) while animals held a sequence of two cued locations in memory over a short delay. We found that stimulation affected the order in which animals saccaded to the locations, but not the memory for which locations were cued. These results imply that memory for sequential order can be dissociated from that of its components. Furthermore, stimulation of the SEF appeared to bias sequence endpoints to converge toward a location in contralateral space, suggesting that this area encodes sequences in terms of their endpoints rather than their individual components

    Effect of Multivitamin Supplementation on Measles Vaccine Response among HIV-exposed Uninfected Tanzanian Infants.

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    Immunization and nutritional interventions are mainstays of child health programs in sub-Saharan Africa, yet few published data exist on their interactions. HIV-exposed (but uninfected) infants enrolled in a randomized placebo-controlled trial of multivitamin supplements (vitamins B complex, C, and E) conducted in Tanzania were sampled for an assessment of measles IgG quantity and avidity at 15 to 18 months. Infants were vaccinated between 8.5 and 12 months of age, and all mothers received high-dose multivitamins as the standard of care. Of 201 HIV-exposed infants who were enrolled, 138 (68.7%) were seropositive for measles. There were no effects of infant multivitamin supplementation on measles seroconversion proportions, IgG concentrations, or IgG avidity (P > 0.05). The measles seroconversion proportion was greater for HIV-exposed infants vaccinated at 10 to 11 months of age than for those vaccinated at 8.5 to 10 months (P = 0.032) and greater for infants whose mothers had a CD4 T-cell count of <200 cells/μl than for infants whose mothers had a CD4 T-cell count of >350 cells/μl (P = 0.039). Stunted infants had a significantly decreased IgG quantity compared to nonstunted infants (P = 0.012). As for measles avidity, HIV-exposed infants vaccinated at 10 to 11 months had increased antibody avidity compared to those vaccinated at 8.5 to 10 months (P = 0.031). Maternal CD4 T-cell counts of <200 cells/μl were associated with decreased avidity compared to counts of >350 cells/μl (P = 0.047), as were lower infant height-for-age z-scores (P = 0.016). Supplementation with multivitamins containing B complex, C, and E does not appear to improve measles vaccine responses for HIV-exposed infants. Studies are needed to better characterize the impact of maternal HIV disease severity on the immune system development of HIV-exposed infants and the effect of malnutrition interventions on vaccine responses. (This study has been registered at ClinicalTrials.gov under registration no. NCT00197730.)
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