Effects of hole-boring and relativistic transparency on particle acceleration in overdense plasma irradiated by short multi-PW laser pulses

Propagation of short and ultra-intense laser pulses in a semi-infinite space of overdense hydrogen plasma is analyzed via fully-relativistic, real geometry particle-in-cell (PIC) simulations including radiation friction. The relativistic transparency and hole-boring regimes are found to be sensitive to the transverse plasma field, backward light reflection, and laser pulse filamentation. For laser intensities approaching $I\sim10^{24}$ W/cm$^2$ the direct laser acceleration of protons, along with ion Coulomb explosion, results in their injection into the acceleration phase of the compressed electron wave at the front of the laser pulses. The protons are observed to be accelerated up to 10-20 GeV with densities around a few times the critical density. The effect strongly depends on initial density and laser intensity disappearing with initial density increase and intensity decrease

Orientational Ordering of Nonplanar Phthalocyanines on Cu(111): Strength and Orientation of the Electric Dipole Moment

In order to investigate the orientational ordering of molecular dipoles and the associated electronic properties, we studied the adsorption of chlorogallium phthalocyanine molecules (GaClPc, Pc=C_32N_8H_16) on Cu(111) using the X-ray standing wave technique, photoelectron spectroscopy, and quantum chemical calculations. We find that for sub-monolayer coverages on Cu(111) the majority of GaClPc molecules adsorb in a 'Cl-down' configuration by forming a covalent bond to the substrate. For bilayer coverages the XSW data indicate a co-existence of the 'Cl-down' and 'Cl-up' configuration on the substrate. The structural details established for both cases and supplementary calculations of the adsorbate system allow us to analyze the observed change of the work function.Comment: 4 pages, 4 figures, accepted for publication in Phys. Rev. Let

Donor killer immunoglobulin-like receptor haplotype B/x induces severe acute graft-versus-host disease in the presence of HLA mismatch in T-cell replete hematopoietic cell transplantation.

新潟大学博士（医学）Natural killer cells have been identified as a mediator of alloimmune reactions in allogeneic hematopoietic stem cell transplantation (HSCT). Killer immunoglobulin-like receptors (KIRs) are an important determinant of natural killer cell function. The relationship between KIR genotypes/haplotypes and clinical outcomes of allogeneic HSCT is complex and inconsistent among several reports. We assessed the clinical impact of KIR haplotype on T cell–replete allogeneic HSCTs performed in a single Japanese center for hematological malignancies (n = 106). A comparison of 2 groups, donor haplotypes A/A and B/x, revealed no significant differences in overall survival, relapse, and nonrelapse mortality. However, grade III to IV acute graft-versus-host disease (GVHD) occurred significantly more frequently in the KIR haplotype B/x group (A/A versus B/x: 4.9% versus 20.0%; P = .02). This was even more evident when HLA mismatch was present. The highest incidences of grade II to IV and grade III to IV acute GVHD were observed in patients who received allografts from HLA-mismatched donors with KIR haplotype B/x. These data highlight the importance of KIR genotyping in donor matching, especially when HLA mismatch allogeneic grafting is planned.学位の種類: 博士（医学）. 報告番号: 甲第4261号. 学位記番号: 新大院博（医）甲第739号. 学位授与年月日: 平成29年3月23日Biology of Blood and Marrow Transplantation 23(4)606-611,2017新大院博（医）甲第739号thesi

Photoelectron detection from transient species in organic semiconducting thin films by dual laser pulse irradiation

An Nd3+:YAG pulsed laser was employed as a light source for two-photon photoemission from organic semiconducting thin films in low vacuum and air. Photoionization by the two-photon process was confirmed in both the environments by measuring photoemission current. By constructing a pump–probe system, photoemissions from transient species formed by the pump light irradiation were detected by probe light irradiation as a result of a linear increase in the photocurrent with the pump power via a one-photon process. Thus, we propose a novel method called two-photon photoelectron yield spectroscopy to determine the excited-state energy levels in ambient environments

胃がん検診用高濃度硫酸バリウムの物理特性

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Charge coupling in multi-stage laser wakefield acceleration

The multi-stage technique for laser driven acceleration of electrons become a critical part of full-optical, jitter-free accelerators. Use of several independent laser drivers and shorter length plasma targets allows the stable and reproducible acceleration of electron bunches (or beam) in the GeV energies with lower energy spreads. At the same time the charge coupling, necessary for efficient acceleration in the consecutive acceleration stage(s), depends collectively on the parameters of the injected electron beam, the booster stage, and the non-linear transverse dynamics of the electron beam in the laser pulse wake. An unmatched electron beam injected in the booster stage(s), and its non-linear transverse evolution may result in perturbation and even reduction of the field strength in the acceleration phase of the wakefield. Analysis and characterization of charge coupling in multi-stage laser wakefield acceleration (LWFA) become ultimately important. Here, we investigate two-stage LWFA via fully relativistic multi-dimensional particle-in-cell simulations, and underlying the most critical parameters, which affect the efficient coupling and acceleration of the electron beam in the booster stage.Comment: 10 figure