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Global discovery of adaptive mutations.
Although modern DNA sequencing enables rapid identification of genetic variation, characterizing the phenotypic consequences of individual mutations remains a labor-intensive task. Here we describe array-based discovery of adaptive mutations (ADAM), a technology that searches an entire bacterial genome for mutations that contribute to selectable phenotypic variation between an evolved strain and its parent. We found that ADAM identified adaptive mutations in laboratory-evolved Escherichia coli strains with high sensitivity and specificity
Suicide related ideation and behavior among Canadian gay and bisexual men: a syndemic analysis
Gender-Specific Situational Correlates of Syringe Sharing during a Single Injection Episode
Ce document est la pré-publication d'un article paru dans AIDS and Behavior 2011; 15(1): 75-85 url: http://link.springer.com/journal/volumesAndIssues/10461IRSC et FRSQ Réseau SIDA et maladies infectieuse
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