305 research outputs found
Myanmar Climate-Smart Agriculture Strategy
Myanmar has committed to apply CSA to contribute to regional food security and environmental protection during the 24th ASEAN Summit on May 10, 2014. The Myanmar CSA strategy encompasses the development of technical, policy and investment conditions to achieve a sustainable agricultural development for food security and nutrition through climate-resilient and sustainable agriculture. Myanmar’s CSA strategy aims to be socially, culturally and politically appropriate, environment-friendly and economically feasible to promote and attain sustainable agriculture, food security and nutrition, agricultural development and climate change adaptation and mitigation. Myanmar’s CSA strategy also aims to provide context and analysis for addressing agriculture in international climate negotiations to better inform climate negotiators and other stakeholders by identifying options and unpacking issues of interest
Caught between COVID-19, Coup and Conflict—What Future for Myanmar Higher Education Reforms?
On 1 February 2021, Myanmar military dictators seized power from the elected government and halted the country’s budding reform process. This article explores how Myanmar’s higher education (HE) sector was affected by the coup and COVID-19 and how this has resulted in societal conflict. The article reviews first the history of military coups, then the education reforms in general and what was done in HE, before discussing the effects of COVID-19 and the coup on the sector. Voices from HE teaching staff show the tension in the role of HE as a vehicle for reform and promulgation of those in power. The article argues that the national vision propagated by Myanmar’s HE sector is juxtaposed to that propagated by the Tatmadaw, both claiming to represent Myanmar’s future. This research highlights the dual forces of the COVID-19 pandemic and military coup at a crucial time for HE reforms in a fragile, conflict-affected state, with the future of the reform goals of equity and equality of the sector at stake
Evaluating the reliability of non-specialist observers in the behavioural assessment of semi-captive Asian elephant welfare
Recognising stress is an important component in maintaining the welfare of captive animal populations, and behavioural observation provides a rapid and non-invasive method to do this. Despite substantial testing in zoo elephants, there has been relatively little interest in the application of behavioural assessments to the much larger working populations of Asian elephants across Southeast Asia, which are managed by workers possessing a broad range of behavioural knowledge. Here, we developed a new ethogram of potential stress- and work-related behaviour for a semi-captive population of Asian elephants. We then used this to collect observations from video footage of over 100 elephants and evaluated the reliability of behavioural welfare assessments carried out by non-specialist observers. From observations carried out by different raters with no prior experience of elephant research or management, we tested the reliability of observations between-observers, to assess the general inter-observer agreement, and within-observers, to assess the consistency in behaviour identification. The majority of ethogram behaviours were highly reliable both between- and within-observers, suggesting that overall, behaviour was highly objective and could represent easily recognisable markers for behavioural assessments. Finally, we analysed the repeatability of individual elephant behaviour across behavioural contexts, demonstrating the importance of incorporating a personality element in welfare assessments. Our findings highlight the potential of non-expert observers to contribute to the reliable monitoring of Asian elephant welfare across large captive working populations, which may help to both improve elephant wellbeing and safeguard human workers
Spread of artemisinin resistance in Plasmodium falciparum malaria.
BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia and now poses a threat to the control and elimination of malaria. Mapping the geographic extent of resistance is essential for planning containment and elimination strategies. METHODS: Between May 2011 and April 2013, we enrolled 1241 adults and children with acute, uncomplicated falciparum malaria in an open-label trial at 15 sites in 10 countries (7 in Asia and 3 in Africa). Patients received artesunate, administered orally at a daily dose of either 2 mg per kilogram of body weight per day or 4 mg per kilogram, for 3 days, followed by a standard 3-day course of artemisinin-based combination therapy. Parasite counts in peripheral-blood samples were measured every 6 hours, and the parasite clearance half-lives were determined. RESULTS: The median parasite clearance half-lives ranged from 1.9 hours in the Democratic Republic of Congo to 7.0 hours at the Thailand-Cambodia border. Slowly clearing infections (parasite clearance half-life >5 hours), strongly associated with single point mutations in the "propeller" region of the P. falciparum kelch protein gene on chromosome 13 (kelch13), were detected throughout mainland Southeast Asia from southern Vietnam to central Myanmar. The incidence of pretreatment and post-treatment gametocytemia was higher among patients with slow parasite clearance, suggesting greater potential for transmission. In western Cambodia, where artemisinin-based combination therapies are failing, the 6-day course of antimalarial therapy was associated with a cure rate of 97.7% (95% confidence interval, 90.9 to 99.4) at 42 days. CONCLUSIONS: Artemisinin resistance to P. falciparum, which is now prevalent across mainland Southeast Asia, is associated with mutations in kelch13. Prolonged courses of artemisinin-based combination therapies are currently efficacious in areas where standard 3-day treatments are failing. (Funded by the U.K. Department of International Development and others; ClinicalTrials.gov number, NCT01350856.)
Asian elephants exhibit post-reproductive lifespans
Background The existence of extended post-reproductive lifespan is an evolutionary puzzle, and its taxonomic prevalence is debated. One way of measuring post-reproductive life is with post-reproductive representation, the proportion of adult years lived by females after cessation of reproduction. Analyses of post-reproductive representation in mammals have claimed that only humans and some toothed whale species exhibit extended post-reproductive life, but there are suggestions of a post-reproductive stage for false killer whales and Asian elephants. Here, we investigate the presence of post-reproductive lifespan in Asian elephants using an extended demographic dataset collected from semi-captive timber elephants in Myanmar. Furthermore, we investigate the sensitivity of post-reproductive representation values to availability of long-term data over 50 years. Results We find support for the presence of an extended post-reproductive stage in Asian elephants, and that post-reproductive representation and its underlying demographic rates depend on the length of study period in a long-lived animal. Conclusions The extended post-reproductive lifespan is unlikely due to physiological reproductive cessation, and may instead be driven by mating preferences or condition-dependent fertility. Our results also show that it is crucial to revisit such population measures in long-lived species as more data is collected, and if the typical lifespan of the species exceeds the initial study period
Testing a brief web-based intervention to increase recognition of tobacco constituents
Objective: We examined website formats to increase smokers\u27 recognition of harmful and potentially harmful constituents (HPHCs) in cigarettes.
Methods: Adult, daily smokers (N = 279) were randomized to view a brief, single-page study website showing HPHC names and uses. The intervention site was tailored + interactive, labeled by cigarette brand/subbrand showing color imagery and pop-up boxes; the generic + static website (control) was unbranded in greyscale. Eye tracking equipment measured attention (dwell time) to precise website features. Linear regression analyses compared attention to HPHC descriptions and the correct recognition of 15 HPHC chemicals. A randomly selected sub-sample (N = 30) of participants qualitatively rated website usability.
Results: Despite spending less dwell time on the HPHC text and entire website, adult smokers who viewed the generic + static website had greater improvement in HPHC recognition compared to the tailored + interactive website (4.6 vs 3.6; p = .02); this finding contrasts with current literature on tailoring and interactivity. Both websites were rated highly on ease-of-use and readability.
Conclusions: Basic formats and narrative HPHC Web-based content attracted less visual attention, yet increased recognition of these chemicals in cigarettes, compared to brand-tailored, interactive web-based content
Autologous/Allogeneic Hematopoietic Cell Transplantation (HCT) Versus Tandem Autologous Transplantation for Multiple Myeloma - Comparison of Long Term Post Relapse Survival
Shining light on data-poor coastal fisheries
This is the final version. Available on open access from Frontiers Media via the DOI in this recordData Availability Statement:
VIIRS Boat Detection data productmade available open access by the Earth Observation Group, Payne Institute for Public Policy (https://eogdata.mines.edu/vbd/). The other datasets presented in this article are not readily available because data requests need to be made directly to the WCS Myanmar offices. Requests to access the datasets should be directed to WCS Myanmar, [email protected] fisheries provide livelihoods and sustenance for millions of people globally but are often poorly documented. Data scarcity, particularly relating to spatio-temporal trends in catch and effort, compounds wider issues of governance capacity. This can hinder the implementation and effectiveness of spatial tools for fisheries management or conservation. This issue is acute in developing and low income regions with many small-scale inshore fisheries and high marine biodiversity, such as Southeast Asia. As a result, fleets often operate unmonitored with implications for target and non-target species populations and the wider marine ecosystem. Novel and cost-effective approaches to obtain fisheries data are required to monitor these activities and help inform sustainable fishery and marine ecosystem management. One such example is the detection and numeration of fishing vessels that use artificial light to attract catch with nighttime satellite imagery. Here we test the efficiency and application value of nighttime satellite imagery, in combination with landings data and GPS tracked vessels, to estimate the footprint and biomass removal of an inshore purse seine fishery operating within a region of high biodiversity in Myanmar. By quantifying the number of remotely sensed vessel detections per month, adjusted for error by the GPS tracked vessels, we can extrapolate data from fisher logbooks to provide fine-scale spatiotemporal estimates of the fishery’s effort, value and biomass removal. Estimates reveal local landings of nearly 9,000 mt worth close to $4 million USD annually. This approach details how remote sensed and in situ collected data can be applied to other fleets using artificial light to attract catch, notably inshore fisheries of Southeast Asia, whilst also providing a much-needed baseline understanding of a data-poor fishery’s spatiotemporal activity, biomass removal, catch composition and landing of vulnerable species.Wildlife Conservation Societ
Is bigger better? The relationship between size and reproduction in female Asian elephants
The limited availability of resources is predicted to impose trade-offs
between growth, reproduction and self-maintenance in animals. However,
although some studies have shown that early reproduction suppresses
growth, reproduction positively correlates with size in others. We use
detailed records from a large population of semi-captive elephants in
Myanmar to assess the relationships between size (height and weight),
reproduction and survival in female Asian elephants, a species
characterized by slow, costly life history. Although female height gain
during the growth period overlapped little with reproductive onset in
the population, there was large variation in age at first reproduction
and only 81% of final weight had been reached by peak age of
reproduction at the population level (19 years). Those females beginning
reproduction early tended to be taller and lighter later in life,
although these trends were not significant. We found that taller females
were more likely to have reproduced by a given age, but such effects
diminished with age, suggesting there may be a size threshold to
reproduction which is especially important in young females. Because
size was not linked with female survival during reproductive ages, the
diminishing effect of height on reproduction with age is unlikely to be
due to biased survival of larger females. We conclude that although
reproduction may not always impose significant costs on growth, height
may be a limiting factor to reproduction in young female Asian
elephants, which could have important implications considering their
birth rates are low and peak reproduction is young – 19 years in this
population. © 2017 European Society For Evolutionary Biology. Journal of
Evolutionary Biology © 2017 European Society For Evolutionary Biology</p
Host immunity and the assessment of emerging artemisinin resistance in a multinational cohort
38 Artemisinin-resistant falciparum malaria, defined by a slow-clearance phenotype and the presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally-acquired immunity to malaria clears parasites independently of antimalarial drugs. We hypothesise that between- and within-population variations in host immunity influence parasite clearance after artemisinin treatment and the interpretation of emerging artemisinin resistance. Antibodies specific to 12 P. falciparum sporozoite and blood-stage antigens were determined in 959 patients (from 11 sites in Southeast Asia) participating in a multinational cohort study assessing parasite clearance half-life (PCt½) after artesunate treatment and kelch13 mutations. Linear mixed-effects modelling of pooled individual patient data assessed the association between antibody responses and PCt½. P. falciparum antibodies were lowest in areas where the prevalence of kelch13 mutations and slow PCt½ were highest (Spearman ρ = -0·90 (95% CI: -0·97, -0·65) and -0·94 (-0·98, -0·77) respectively). P. falciparum antibodies were associated with faster PCt½ (mean difference in PCt½ according to seropositivity -0·16 to -0·65 hours depending on antigen); antibodies have a greater impact on the clearance of kelch13 mutant compared to wild-type parasites (mean difference in PCt½ according to seropositivity -0·22 to -0·61 hours faster in kelch13 mutants compared to wild-type parasites). Naturally-acquired immunity accelerates the clearance of artemisinin-resistant parasites in patients with falciparum malaria, and may confound the current working definition of artemisinin resistance. Immunity may also play an important role in the emergence and transmission potential of artemisinin-resistant parasites
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