1,156 research outputs found

    A comparative study between deep learning algorithm and bayesian network on Advanced Persistent Threat (APT) attack detection

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    Advanced Persistent Threat (APT) attacks are a major concern for the cybersecurity in digital world due to their advanced nature. Attackers are skilful to cause maximal destruction for targeted cyber environment. These APT attacks are also well funded by governments in many cases. The APT attacker can achieve his hostile goals by obtaining information and gaining financial benefits regarding the infrastructure of a network. It is highly important to study proper countermeasures to detect these attacks as early as possible due to sophisticated methods. It is difficult to detect this type of attack since the network may crash because of high traffic. Hence, in this study, this research is to study the comparison between Multilayer Perceptron and Naïve-Bayes of APT attack detection. Since the APT attack is persistent and permanent presence in the victim system, so minimal false positive rate (FPR) and high accuracy detection is required to detect the APT attack detection. Besides, Multilayer Perceptron algorithm has high true positive rate (TPR) in the detection of APT attack compared to Naïve Bayes algorithm. This means that Multilayer Perceptron algorithm can detect APT attack more accurately. Based on the result, it also can conclude that the lower the false positive rate (FPR), the more accurate to detect APT attack. Lastly, the research would also help to spread the awareness about the APT intrusion where it possibly can cause huge damage to everyone

    Fabrication of Photovoltaic Cell From Rhenium Containing Polymer

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    Photovoltaic devices were fabricated using rhenium bis(arylimino) acenaphthene (DIAN) complex containing poly(p-phenylenevinylene). These polymers absorb strongly in the visible region at ca. 440-550 nm. In addition, this type of transition metal based polymers have been shown to exhibit large photo-sensitivity due to the presence of the rhenium complex, which has a relatively long-lived Metal-to-Ligand Charge Transfer (MLCT) character. By using this type of polymers, the metal content can be adjusted easily by simply changing the monomer feed ratio. Moreover, the excited state properties and electronic absorption properties can be modified by varying the structure of the diimine ligand coordinated to the metal. This approach allows us to fine-tune the absorption spectra of the polymers by employing different types of rhenium complex derivatives. PEDOT:PSS and PTCDI were used as the hole and electron transport layers, respectively. The ITO/PEDOT:PSS/DIAN-PPV/PTCDI/Al devices were found to exhibit photovoltaic response under the illumination of AMI solar radiation. The short-circuit current ISC, open-circuit voltage V OC, and the fill factor FF were measured to be 38 μA/cm 2, 0.93 V and 0.21 respectively. Another photovoltaic device was prepared with the structure ITO/PEDOT:PSS/DIAN-PPV:TiO2/PTCDI/Al and its photovoltaic properties were studied. The presence of TiO2 will assist the electron transport of the DIAN-PPV to the PTCDI, in which the electrons can be collected at the aluminium electrode. The short-circuit current ISC open-circuit voltage VOC, and the fill factor FF were measured to be 51 μA/cm2, 1.18 V and 0.12 respectively. It was observed that the power conversion efficiency of photovoltaic devices related closely to the rhenium content and the structure of the rhenium complex used.published_or_final_versio

    Preliminary work on coconut milk fouling deposits study

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    The characterizations of coconut milk fouling deposits formed during pasteurization process at temperature from 70 to 80ºC were investigated. Both in-situ (using lab-scale plate heat exchanger) and ex-situ methods (using shakable water bath) were applied in preparing the fouling sample and for cleaning study. A few microanalyses such as proximate analysis, texture analysis and microstructure analysis were carried out to examine the characteristics of the coconut milk fouling deposits. Selection of raw material and determination of the optimal process parameters for pasteurization process were done to obtain a typical pasteurization condition as applied in the coconut milk product industry in Malaysia. The changes of the overall heat transfer coefficient (U) during the process were studied. The removal/cleaning of coconut milk fouling deposit was also studied at 80°C, 2 LPM and with 2 %V/V hydroxide of alkaline solution (optimal condition obtained from ex-situ method). The results indicate that fouling period was occurred during coconut milk pasteurization and it caused a resistance to heat transfer. Coconut milk fouling deposit which contains of high fat content (29.25%) can be removed by applying single stage clean-in-place (CIP) method with alkaline solution. The factors causing fouling were studied

    CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

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    Macrophages abundantly found in the tumor microenvironment enhance malignancy(1). At metastatic sites a distinct population of metastasis associated macrophages (MAMs) promote tumor cell extravasation, seeding and persistent growth(2). Our study has defined the origin of these macrophages by showing Gr1+ inflammatory monocytes (IMs) are preferentially recruited to pulmonary metastases but not primary mammary tumors, a process also found for human IMs in pulmonary metastases of human breast cancer cells. The recruitment of these CCR2 (receptor for chemokine CCL2) expressing IMs and subsequently MAMs and their interaction with metastasizing tumor cells is dependent on tumor and stromal synthesized CCL2 (FigS1). Inhibition of CCL2/CCR2 signaling using anti-CCL2 antibodies blocks IM recruitment and inhibits metastasis in vivo and prolongs the survival of tumor-bearing mice. Depletion of tumor cell-derived CCL2 also inhibits metastatic seeding. IMs promote tumor cell extravasation in a process that requires monocyte-derived VEGF. CCL2 expression and macrophage infiltration are correlated with poor prognosis and metastatic disease in human breast cancer (Fig S2)(3-6). Our data provides the mechanistic link between these two clinical associations and indicates new therapeutic targets for treating metastatic breast disease

    Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan

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    OBJECTIVE: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. METHODS: Using data from the National Health Insurance (NHI) Research Database in Taiwan, we conducted a nationwide cross-sectional study of data collected from 22 643 748 beneficiaries of the NHI in 2004; among them 1 045 059 individuals had physician-diagnosed gout. We estimated relative risks (RR) of gout in individuals with affected first-degree and second-degree relatives and relative contributions of genes (heritability), common environment shared by family members and non-shared environment to gout susceptibility. RESULTS: RRs for gout were significantly higher in individuals with affected first-degree relatives (men, 1.91 (95% CI 1.90 to 1.93); women, 1.97 (95% CI 1.94 to 1.99)) and also in those with affected second-degree relatives (men, 1.27 (95% CI 1.23 to 1.31); women, 1.40 (95% CI 1.35 to 1.46)). RRs (95% CIs) for individuals with an affected twin, sibling, offspring, parent, grandchild, nephew/niece, uncle/aunt and grandparent were 8.02 (6.95 to 9.26), 2.59 (2.54 to 2.63), 1.96 (1.95 to 1.97), 1.93 (1.91 to 1.94), 1.48 (1.43 to 1.53), 1.40 (1.32 to 1.47), 1.31 (1.24 to 1.39), and 1.26 (1.21 to 1.30), respectively. The relative contributions of heritability, common and non-shared environmental factors to phenotypic variance of gout were 35.1, 28.1 and 36.8% in men and 17.0, 18.5 and 64.5% in women, respectively. CONCLUSIONS: This population-based study confirms that gout aggregates within families. The risk of gout is higher in people with a family history. Genetic and environmental factors contribute to gout aetiology, and the relative contributions are sexually dimorphic

    Impacts of risk based capital regulation in Malaysian Islamic insurers (Takaful)

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    Risk Based Capital framework for Takaful operators (RBCT) is enforced by the Central Bank of Malaysia with the aim to ensure that Takaful operators have adequate capital to provide sound financial service. The objectives of this article is to examine the impacts of RBCT on efficiency, productivity and competitiveness level of Family Takaful Operators (FTO) and the relationship between efficiency and competitiveness in FTO in Malaysia. This study employs three methods namely Data Envelopment Analysis (DEA), Malmquist Productivity Index (MPI) and Panzar Rosse (PR) to investigate the impacts of RBC on the efficiency, productivity and competitiveness of FTO in Malaysia. The efficiency results indicate that after RBCT comes into effect, the cost efficiency has achieved higher efficient level. Although the productivity efficiency are improving, the technological systems of FTO are yet to achieve a reasonable level. From competitiveness results, the FTO are less competitive prior the implementation of RBCT, but has become more competitive after the regulation of RBCT framework. Furthermore, the more efficient of a Takaful market, the more competitive the market is. The implication of this study is that regulators need to impose prudent risk based capital regulation because it will improve the efficiency and competitiveness of Islamic insurers

    Analysis of the impact of length of stay on the quality of service experience, satisfaction and loyalty

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    Although length of stay is a relevant variable in destination management, little research has been produced connecting it with tourists' post-consumption behaviour. This research compares the post-consumption behaviour of same-day visitors with overnight tourists in a sample of 398 domestic vacationers at two Mediterranean heritage-and-beach destinations. Although economic research on length of stay posits that there are destination benefits in longer stays, same-day visitors score higher in most of the post-consumption variables under study. Significant differences arise in hedonic aspects of the tourist experience and destination loyalty. Thus, we propose that length of stay can be used as a segmentation variable. Furthermore, destination management organisations need to consider length of stay when designing tourism policies. The tourist product and communication strategies might be adapted to different vacation durations

    ROCK Inhibitor Is Not Required for Embryoid Body Formation from Singularized Human Embryonic Stem Cells

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    We report a technology to form human embryoid bodies (hEBs) from singularized human embryonic stem cells (hESCs) without the use of the p160 rho-associated coiled-coil kinase inhibitor (ROCKi) or centrifugation (spin). hEB formation was tested under four conditions: +ROCKi/+spin, +ROCKi/-spin, -ROCKi/+spin, and -ROCKi/-spin. Cell suspensions of BG01V/hOG and H9 hESC lines were pipetted into non-adherent hydrogel substrates containing defined microwell arrays. hEBs of consistent size and spherical geometry can be formed in each of the four conditions, including the -ROCKi/-spin condition. The hEBs formed under the -ROCKi/-spin condition differentiated to develop the three embryonic germ layers and tissues derived from each of the germ layers. This simplified hEB production technique offers homogeneity in hEB size and shape to support synchronous differentiation, elimination of the ROCKi xeno-factor and rate-limiting centrifugation treatment, and low-cost scalability, which will directly support automated, large-scale production of hEBs and hESC-derived cells needed for clinical, research, or therapeutic applications

    Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity

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    Urban Biodiversity and Landscape Ecology: Patterns, Processes and Planning

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    Effective planning for biodiversity in cities and towns is increasingly important as urban areas and their human populations grow, both to achieve conservation goals and because ecological communities support services on which humans depend. Landscape ecology provides important frameworks for understanding and conserving urban biodiversity both within cities and considering whole cities in their regional context, and has played an important role in the development of a substantial and expanding body of knowledge about urban landscapes and communities. Characteristics of the whole city including size, overall amount of green space, age and regional context are important considerations for understanding and planning for biotic assemblages at the scale of entire cities, but have received relatively little research attention. Studies of biodiversity within cities are more abundant and show that longstanding principles regarding how patch size, configuration and composition influence biodiversity apply to urban areas as they do in other habitats. However, the fine spatial scales at which urban areas are fragmented and the altered temporal dynamics compared to non-urban areas indicate a need to apply hierarchical multi-scalar landscape ecology models to urban environments. Transferring results from landscape-scale urban biodiversity research into planning remains challenging, not least because of the requirements for urban green space to provide multiple functions. An increasing array of tools is available to meet this challenge and increasingly requires ecologists to work with planners to address biodiversity challenges. Biodiversity conservation and enhancement is just one strand in urban planning, but is increasingly important in a rapidly urbanising world
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