Gated Convolutional Bidirectional Attention-based Model for Off-topic Spoken Response Detection

Off-topic spoken response detection, the task aiming at predicting whether a response is off-topic for the corresponding prompt, is important for an automated speaking assessment system. In many real-world educational applications, off-topic spoken response detectors are required to achieve high recall for off-topic responses not only on seen prompts but also on prompts that are unseen during training. In this paper, we propose a novel approach for off-topic spoken response detection with high off-topic recall on both seen and unseen prompts. We introduce a new model, Gated Convolutional Bidirectional Attention-based Model (GCBiA), which applies bi-attention mechanism and convolutions to extract topic words of prompts and key-phrases of responses, and introduces gated unit and residual connections between major layers to better represent the relevance of responses and prompts. Moreover, a new negative sampling method is proposed to augment training data. Experiment results demonstrate that our novel approach can achieve significant improvements in detecting off-topic responses with extremely high on-topic recall, for both seen and unseen prompts.Comment: ACL2020 long pape

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation.

Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against macrophage foam cell formation, our recent understanding of the influence that apoE can exert to control atherosclerosis has significantly widened. Among apoE's newfound athero-protective properties include an ability to control exaggerated hematopoiesis, blood monocyte activation and aortic stiffening in mice with hyperlipidemia. Mechanisms responsible for these exciting new properties extend beyond apoE's ability to prevent cellular lipid excess. Rather, new findings have revealed a role for apoE in regulating microRNA-controlled cellular signaling in cells of the immune system and vascular wall. Remarkably, infusions of apoE-responsive microRNA mimics were shown to substitute for apoE in protecting against systemic and vascular inflammation to suppress atherosclerosis in mice with hyperlipidemia. Finally, more recent evidence suggests that apoE may control the release of microvesicles that could modulate cellular signaling, inflammation and atherosclerosis at a distance. These exciting new findings position apoE within the emerging field of intercellular communication that could introduce new approaches to control atherosclerosis cardiovascular disease

What Causes the Volatility of the Balancing Item?

This paper analyzes the impacts of timing errors, capital flows and economic openness on the behavior of the balancing item. We choose Norway, Sweden, Philippines and South Africa as sample countries where the size of the balancing item is often excess the IMF's criterion of ‘smallness'. The empirical results show that the sources of the volatility of the balancing item are different among these four countries.Balancing item, Balance of payments