33 research outputs found

    The Role of Albumin-Globulin Ratio on Predicting Postoperative Pancreatic Fistula in Pancreaticoduodenectomy Patients

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    Background and aim: The albumin-globulin ratio (AGR) is one of the indicators of inflammation and immunity and it has a prognostic significance in many malignant diseases. Previous studies have shown the relationship between inflammatory mediators and POPF. This study aimed to evaluate the relation of AGR, which is a relatively new indicator, with postoperative pancreatic fistula (POPF). Methods: Pancreaticoduodenectomy (PD) patients between 2017 and 2020 were retrospectively analyzed and divided into two groups as those with and without clinically relevant POPF (CR-POPF). They were compared in terms of preoperative-postoperative AGR and clinicodemographic characteristics. AGR was calculated as Albumin / (Total protein-albumin) and the cutoff point for AGR was determined according to Youden&amp;rsquo;s index. Results: CR-POPF developed in 21% of 121 patients who underwent PD. There was no difference between the groups in terms of age, gender, comorbid disease status, pancreatic duct width, and anastomosis technique. Preoperative and postoperative day-3 (POD3) albumin levels and AGR were found to be significantly lower in the CR-POPF group. Multivariate analysis showed that AGR and pancreatic tissue stiffness are independent risk factors for the development of POPF. Conclusions: Low AGR is an independent risk factor for the development of CR-POPF. To reduce the incidence of POPF, this ratio should be tried to be kept at an optimal level.</jats:p

    Why People Vote for Thin-Centred Ideology Parties? A Multi-Level Multi-Country Test of Individual and Aggregate Level Predictors

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    The present research investigates the individual and aggregate level determinants of support for thin-centred ideology parties across 23 European countries. Employing a multilevel modelling approach, we analysed European Social Survey data round 7 2014 (N = 44000). Our findings show that stronger identification with one’s country and confidence in one’s ability to influence the politics positively but perceiving the system as satisfactory and responsive; trusting the institutions and people, and having positive attitudes toward minorities, i.e., immigrants and refugees, negatively predict support for populist and single issue parties. The level of human development and perceptions of corruption at the country level moderate these effects. Thus, we provide the first evidence that the populist surge is triggered by populist actors’ capacity to simultaneously invoke vertical, “ordinary” people against “the elites”, and horizontal, “us” against “threatening aliens”, categories of people as well as the sovereignty of majority over minorities. These categories and underlying social psychological processes of confidence, trust, and threats are moderated by the general level of human development and corruption perceptions in a country. It is, therefore, likely that voting for populist parties will increase as the liberally democratic countries continue to prosper and offer better opportunities for human development. Stronger emphasis on safeguarding the integrity of the economic and democratic institutions, as our findings imply, and preserving their ethical and honest, i.e., un-corrupt, nature can keep this surge under check
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