7,998 research outputs found
Finite element analysis of a deployable space structure
To assess the dynamic characteristics of a deployable space truss, a finite element model of the Scientific Applications Space Platform (SASP) truss has been formulated. The model incorporates all additional degrees of freedom associated with the pin-jointed members. Comparison of results with SPAR models of the truss show that the joints of the deployable truss significantly affect the vibrational modes of the structure only if the truss is relatively short
Long-term survival for a cohort of adults with cerebral palsy
The aim of this study was to investigate long-term survival and examine causes of death in adult patients with cerebral palsy (CP). A 1940–1950 birth cohort based on paediatric case referral allows for long-term survival follow-up. Survival is analyzed by birth characteristics and severity of disability from age 20 years (and age 2y for a subset of the data). Survival outcome compared with that expected in the general population based on English life tables. The main cohort consisted of 341 individuals, with 193 males and 148 females. Conditional on surviving to age 20 years, almost 85% of the cohort survived to age 50 years (a comparable estimate for the general population is 96%). Very few deaths were attributed to CP for those people dying over 20 years of age. Females survived better than males. However, females faced a greater increase in risk relative to the general population than did males. We conclude that survival outlook is good though lower than in the general population. The relative risk of death compared with the UK population decreases with age, although it shows some indication of rising again after age 50 years. Many more deaths were caused by diseases of the respiratory system among those dying in their 20s and 30s than would be expected in the general population. Many fewer deaths than expected in this age group are caused by injuries and accidents. For those people who die in their 40s and 50s, an increase in deaths due to diseases of the circulatory system and neoplasms is observed. More deaths than expected in this age group are due to diseases of the nervous system
Distribution and incidence of viruses in Irish seed potato crops
peer-reviewedVirus diseases are of key importance in potato production and in particular for the production of disease-free potato seed. However, there is little known about the frequency and distribution of potato virus diseases in Ireland. Despite a large number of samples being tested each year, the data has never been collated either within or across years. Information from all known potato virus testing carried out in the years 2006–2012 by the Department of Agriculture Food and Marine was collated to give an indication of the distribution and incidence of potato virus in Ireland. It was found that there was significant variation between regions, varieties, years and seed classes. A definition of daily weather data suitable for aphid flight was developed, which accounted for a significant proportion of the variation in virus incidence between years. This use of weather data to predict virus risk could be developed to form the basis of an integrated pest management approach for aphid control in Irish potato crops
Therapeutic radiographers' perceptions of the barriers and enablers to effective smoking cessation support
Introduction: Tobacco smoking during and post radiotherapy is associated with increased treatment
toxicity and increased cancer related mortality. Routine delivery of smoking cessation advice is inconsistent
in practice. This study identifies the key barriers and facilitators to the provision of effective
smoking cessation conversations in radiotherapy practice.
Methods: A baseline questionnaire (n ¼ 43) was used to identify current practice, barriers and facilitators
to smoking cessation in radiotherapy and to inform a topic guide for follow up focus groups (n ¼ 5).
Ethical approval was obtained through the 4 NHS trusts and the Health Research Authority. Focus group
transcription was coded by two researchers.
Results: Therapeutic Radiographers initiate health behaviour conversations with patients; there are a
number of factors that facilitate the likelihood of a health behaviour conversation; indication that a
patient smokes anatomical site and presence of acute effects. Key barriers to smoking cessation provision
include; lack of training, limited knowledge, limitations as a result of poor clinical infrastructure, local
culture and perceptions that patients do not prioritise smoking cessation during treatment.
Conclusion: Therapeutic Radiographers have the motivation to provide smoking cessation advice,
however they require further training to develop knowledge and skills in relation to benefits of smoking
cessation and cessation strategies. Therapeutic Radiographers also expect that patients will respond
negatively to smoking cessation advice, and that this might be damaging to the therapeutic relationship.
Departmental culture and trust infrastructure can also significantly inhibit the provision of smoking
cessation in radiotherapy practice and further support to implement NICE guidance is required
Shielding requirements of a SPECT insert for installation in a PET/MRI system
The objective of this work is to evaluate the shielding requirements of a SPECT insert for installation in the Siemens Biograph mMR in order to perform simultaneous SPECT/MR imaging of the human brain. We intend to use the radionuclides 99mTc, 123I and 111In. The main photopeaks of these radionuclides have the following energies: 140.5, 159.0, 171.3 and 245.4 keV. There is also about ∼3% of emission probability of high energy gamma photons for 123I in the range of 248-784 keV. The main constraints to the design of the gamma shielding are the presence of high energy photons, the weight, the MR compatibility and the PET LSO crystals intrinsic activity. We used GATE to simulate a SPECT acquisition, defining an MRI system with LSO crystals, a partial SPECT ring and a NEMA phantom. We also defined a lead (Pb) base plate (BP) to simulate the support system and three Pb shielding volumes with variable thickness: front and end (FE), back (B), and lateral (L) shield. These volumes reduce interference from out-of-field activity, LSO intrinsic activity and edge effects, respectively. We performed 4 sets of simulations, with variable FE, variable B, variable L and variable BP thickness, respectively, with a NEMA phantom filled with 185 MBq of 123I or 111In. For all simulations, we compared the different energy spectra and count-distribution plots. Results show that a Pb shielding configuration with a thickness of 6 mm-F, 2 mm-E, 3 mm-B, and 5 mm-L is appropriate for the insert. For 123I there is still a high contribution from high energy photons, as the amount of shielding is limited by weight, however this contribution is likely to be overestimated in the simulations as compared to practice. The effect of the LSO intrinsic activity is negligible at the energies of interest
Herbicide impacts on exotic grasses and a population of the critically endangered herb "Calystegia affinis" (Convolvulaceae) on Lord Howe Island
Introduced perennial grasses are capable of altering the habitat of native species, causing reductions in population size and vigour, and potentially affecting life-history processes such as survival, pollination and seedling recruitment. We examined the utility of herbicide treatment on two exotic grasses, Pennisetum clandestinum (Kikuyu) and Stenotaphrum secundatum (Buffalo grass) to restore the habitat of Calystegia affinis, a critically endangered species endemic to Lord Howe and Norfolk Islands. Using two herbicides, Asset (designed to affect only grasses) and Glyphosate (a general herbicide), we compared effectiveness in reducing grass cover on a population of Calystegia affinis. We protected Calystegia plants from the herbicides by ensuring their leaves were covered by plastic bags during herbicide application. Both herbicides were similarly effective in reducing grass cover after four weeks and had no noticeable adverse affect on Calystegia (suggesting the plastic bag protection was effective). After 26 weeks, Glyphosate was more effective in maintaining a reduced grass cover. Plots treated with either herbicide had a greater relative increase in abundance of Calystegia stems compared to untreated controls. The Glyphosate treatment resulted in the greatest relative increase in stem abundance, but this was not significantly greater than in the Asset treatment. We consider that spraying with Glyphosate treatment, with follow-up monitoring and spot-spraying, will assist the recovery of the Calystegia affinis population. Ultimately, the maintenance of a weed-free zone at the forest edge will provide suitable habitat for additional recruitment of this and other native species
Online modelling of water distribution system using Data Assimilation
PublishedConference Proceeding12th International Conference on Computing and Control for the Water Industry, CCWI2013This paper applies Data Assimilation (DA) methods to a Water Distribution System Model to improve the realtime estimation of water demand, and hydraulic system states. A time series model is used to forecast water demands which are used to drive the hydraulic model to predict the future system state. Both water demands and water demand model parameters are corrected via DA methods to update the system state. The results indicate that DA methods improved offline hydraulic modelling predictions. Of the DA methods, the Ensemble Kalman Filter outperformed the Kalman Filter in term of updating demands and water demand model parameters. © 2013 The Authors.The authors are grateful to United Utilities (UU), Mr D. Clucas, Mr T. Allen, Mr N. Croxton and UU hydraulic
modelling team for providing the case study data and supporting financially the STREAM EngD project
Online burst detection in a water distribution system using the Kalman filter and hydraulic modelling
PublishedThis paper presents a burst detection methodology that utilizes distributed real time sensor data in a district metered area using a data assimilation method and a hydraulic model. A sensitivity analysis was applied to evaluate the performance of various burst detection metrics under different conditions, and to identify appropriate thresholds for online burst detection using artificial generated burst events. It was found that the best performing metrics are the corrected flow residual and normalized corrected flow residual. This metric can be effective to detect bursts in a timely and reliable manner within a district metering area under assumed test conditions
The languages of peace during the French religious wars
The desirability of peace was a common topos in sixteenth-century political rhetoric, and the duty of the king to uphold the peace for the benefit of his subjects was also a long-established tradition. However, the peculiar circumstances of the French religious wars, and the preferred royal policy of pacification, galvanized impassioned debate among both those who supported and those who opposed confessional coexistence. This article looks at the diverse ways in which peace was viewed during the religious wars through an exploration of language and context. It draws not only on the pronouncements of the crown and its officials, and of poets and jurists, but also on those of local communities and confessional groups. Opinion was not just divided along religious lines; political imperatives, philosophical positions and local conditions all came into play in the arguments deployed. The variegated languages of peace provide a social and cultural dimension for the contested nature of sixteenth-century French politics. However, they could not restore harmony to a war-torn and divided kingdom
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