171 research outputs found

    Attitudes and perceptions regarding entrepreneurship around the world : a cluster analysis approach

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    Nowadays it is believed that entrepreneurship could be a driving force in growth and develop-ment. For the achievement of a relevant national entrepreneurship rate the social and economic business environment can be crucial. However, despite the international attention given to entrepreneurship, it is not known if it is a global phenomenon or if there are particular regions where the entrepreneurial activity is specially recognized by society. Applying cluster analysis statistical techniques to a dataset gathered by the Global Entrepreneurship Monitor (GEM) and that includes, in 2010, 59 countries this paper intends to identify groups of countries with the same population attitude and perception regarding entrepreneurship

    Attitudes and perceptions regarding entrepreneurship around the world : a cluster analysis approach

    Get PDF
    Nowadays it is believed that entrepreneurship could be a driving force in growth and development. For the achievement of a relevant national entrepreneurship rate the social and economic business environment can be crucial. However, despite the international attention given to entrepreneurship, it is not known if it is a global phenomenon or if there are particular regions where the entrepreneurial activity is specially recognized by society. Applying cluster analysis statistical techniques to a dataset gathered by the Global Entrepreneurship Monitor (GEM) and that includes, in 2010, 59 countries this paper intends to identify groups of countries with the same population attitude and perception regarding entrepreneurship

    Conceitos que caracterizam o mundo espiritual de uma pessoa em unidades fraseológicas com componente onomástico nas línguas tártara, turca e inglesa

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    The article is devoted to comparative analysis of phraseological units describing the spiritual world of a person in Tatar, Turkish and English languages. The concepts of the spiritual world of man are of interest for studying the linguistic picture of the world of three different structured languages. The relevance of the research is determined by the fact that phraseological units are one of the most difficult studies in science linguistics. This study is devoted to the comparative consideration of concepts characterizing the spiritual world of a person through the prism of phraseological units in Tatar, Turkish and English linguistics. The study was conducted at the intersection of linguocognitive, anthropocentric, structural-semantic, communicative-functional paradigms involving a large volume of ethnocultural information of each language.O artigo é dedicado à análise comparativa de unidades fraseológicas que descrevem o mundo espiritual de uma pessoa nas línguas tártara, turca e inglesa. Os conceitos do mundo espiritual do homem são de interesse para estudar a imagem linguística do mundo de três línguas estruturalmente diferentes. A relevância da pesquisa é determinada pelo fato de que as unidades fraseológicas são um dos estudos mais difíceis na ciência linguística. Este estudo é dedicado à consideração comparativa de conceitos que caracterizam o mundo espiritual do homem através do prisma de unidades fraseológicas na linguística tártara, turca e inglesa. O estudo foi realizado na interseção de paradigmas linguocognitivos, antropocêntricos, estruturais-semânticos e comunicativos-funcionais, que envolveram um grande volume de informações etnoculturais de cada língua

    Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

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    [This corrects the article DOI: 10.1186/s13054-016-1208-6.]

    Osteointegration of soft tissue grafts within the bone tunnels in anterior cruciate ligament reconstruction can be enhanced

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    Anterior cruciate ligament reconstruction with a soft tissue autograft (hamstring autograft) has grown in popularity in the last 10 years. However, the issues of a relatively long healing time and an inferior histological healing result in terms of Sharpey-like fibers connection in soft tissue grafts are still unsolved. To obtain a promising outcome in the long run, prompt osteointegration of the tendon graft within the bone tunnel is essential. In recent decades, numerous methods have been reported to enhance osteointegration of soft tissue graft in the bone tunnel. In this article, we review the current literature in this research area, mainly focusing on strategies applied to the local bone tunnel environment. Biological strategies such as stem cell and gene transfer technology, as well as the local application of specific growth factors have been reported to yield exciting results. The use of biological bone substitute and physical stimulation also obtained promising results. Artificially engineered tissue has promise as a solution to the problem of donor site morbidity. Despite these encouraging results, the current available evidence is still experimental. Further clinical studies in terms of randomized control trial in the future should be conducted to extrapolate these basic science study findings into clinical practice. © 2009 Springer-Verlag.postprin

    Plakophilin-3 Is Required for Late Embryonic Amphibian Development, Exhibiting Roles in Ectodermal and Neural Tissues

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    The p120-catenin family has undergone a significant expansion during the evolution of vertebrates, resulting in varied functions that have yet to be discerned or fully characterized. Likewise, members of the plakophilins, a related catenin subfamily, are found throughout the cell with little known about their functions outside the desmosomal plaque. While the plakophilin-3 (Pkp3) knockout mouse resulted in skin defects, we find larger, including lethal effects following its depletion in Xenopus. Pkp3, unlike some other characterized catenins in amphibians, does not have significant maternal deposits of mRNA. However, during embryogenesis, two Pkp3 protein products whose temporal expression is partially complimentary become expressed. Only the smaller of these products is found in adult Xenopus tissues, with an expression pattern exhibiting distinctions as well as overlaps with those observed in mammalian studies. We determined that Xenopus Pkp3 depletion causes a skin fragility phenotype in keeping with the mouse knockout, but more novel, Xenopus tailbud embryos are hyposensitive to touch even in embryos lacking outward discernable phenotypes, and we additionally resolved disruptions in certain peripheral neural structures, altered establishment and migration of neural crest, and defects in ectodermal multiciliated cells. The use of two distinct morpholinos, as well as rescue approaches, indicated the specificity of these effects. Our results point to the requirement of Pkp3 in amphibian embryogenesis, with functional roles in a number of tissue types
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