147 research outputs found
Les enseignants: à la recherche de leur profession
Les Enseignants: à la recherche de leur profession reprend les idées centrales présentées à la Conférence donnée, sur l'invitation de l'ATEE, au Séminaire de Barcelone, en 1993. Cet article est la reproduction du texte de support à la Conférence. Étant donné l'espace disponible, il n'a pas été possible de le travailler dans le sens d'une plus grande problématisation et élaboration théorique
The Effect of Inquiry Learning Strategy versus Expository and Achievement Motivation ON THE Students’ Outcomes in Reading Fiction of Critical Literacy Approach
the aims of this research are to know (1) the difference of students’ outcomes in reading fiction of critical literacy approach between the students taught by inquiry learning strategy and expository learning strategy; (2) the difference of students’ outcomes in reading fiction of critical literacy approach between the students who have high achievement motivation and low achievement motivation; and (3) the interaction between the learning strategy and achievement motivation and the students ‘outcomes in reading fiction of critical literacy approach. The type of this research is factorial approach experiment 2 x 2. The subjects of this research are the students of education of language and Indonesian literary study program, Teachers Training Faculty UNDANA Kupang, consisting of two parallel classes, namely 32 students of experiment group (inquiry) and 31 students of control group (expository) with moderator variable achievement motivation (high and low). The data of research result is processed by ANOVA statistical analysis. The result of research indicates that (1) the use of inquiry learning strategy is more excellent (mean 76,35) comparing to expository learning strategy (mean 71,38) to the students’ outcomes in reading fiction of critical literacy approach; (2) there is a difference of significant students ‘outcomes between the students with high achievement motivation (mean 76,82) and the students with low achievement motivation (mean 70,53); and (3) there is no significant interaction between the learning strategy and achievement motivati
Compilation of a social network lexicon for determining the profile of authors
The use of social networks is steadily increasing worldwide. Hundreds of users daily register in the different existing platforms, therefore, the content extracted from the social networks is fundamental for tasks such as sentiment analysis, detection of author profiles, identification of authors, opinions mining, plagiarism detection, calculation of similarity between texts and to develop robust systems that help to make decisions in related areas such as politics, education, economy, among others. This paper provides a lexical aid for the pre-processing of texts posted in social networks evolved for the subsequent languages: English, Spanish, Dutch and Italian
Projections of Excess Mortality Related to Diurnal Temperature Range Under Climate Change Scenarios: a multi-country modelling study
Various retrospective studies have reported on the increase of mortality risk due to higher diurnal temperature range (DTR). This study projects the effect of DTR on future mortality across 445 communities in 20 countries and regions
Aβ Mediated Diminution of MTT Reduction—An Artefact of Single Cell Culture?
The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT) reduction assay is a frequently used and easily reproducible method to measure beta-amyloid (Aβ) toxicity in different types of single cell culture. To our knowledge, the influence of Aβ on MTT reduction has never been tested in more complex tissue. Initially, we reproduced the disturbed MTT reduction in neuron and astroglia primary cell cultures from rats as well as in the BV2 microglia cell line, utilizing four different Aβ species, namely freshly dissolved Aβ (25-35), fibrillar Aβ (1-40), oligomeric Aβ (1-42) and oligomeric Aβ (1-40). In contrast to the findings in single cell cultures, none of these Aβ species altered MTT reduction in rat organotypic hippocampal slice cultures (OHC). Moreover, application of Aβ to acutely isolated hippocampal slices from adult rats and in vivo intracerebroventricular injection of Aβ also did not influence the MTT reduction in the respective tissue. Failure of Aβ penetration into the tissue cannot explain the differences between single cells and the more complex brain tissue. Thus electrophysiological investigations disclosed an impairment of long-term potentiation (LTP) in the CA1 region of hippocampal slices from rat by application of oligomeric Aβ (1-40), but not by freshly dissolved Aβ (25-35) or fibrillar Aβ (1-40). In conclusion, the experiments revealed a glaring discrepancy between single cell cultures and complex brain tissue regarding the effect of different Aβ species on MTT reduction. Particularly, the differential effect of oligomeric versus other Aβ forms on LTP was not reflected in the MTT reduction assay. This may indicate that the Aβ oligomer effect on synaptic function reflected by LTP impairment precedes changes in formazane formation rate or that cells embedded in a more natural environment in the tissue are less susceptible to damage by Aβ, raising cautions against the consideration of single cell MTT reduction activity as a reliable assay in Alzheimer's drug discovery studies
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