7,275 research outputs found
Proximal business intelligence on the semantic web
This is the post-print version of this article. The official version can be accessed from the link below - Copyright @ 2010 Springer.Ubiquitous information systems (UBIS) extend current Information System thinking to explicitly differentiate technology between devices and software components with relation to people and process. Adapting business data and management information to support specific user actions in context is an ongoing topic of research. Approaches typically focus on providing mechanisms to
improve specific information access and transcoding but not on how the information
can be accessed in a mobile, dynamic and ad-hoc manner. Although web ontology has been used to facilitate the loading of data warehouses, less research has been carried out on ontology based mobile reporting. This paper explores how business data can be modeled and accessed using the web ontology
language and then re-used to provide the invisibility of pervasive access; uncovering
more effective architectural models for adaptive information system strategies of this type. This exploratory work is guided in part by a vision of business intelligence that is highly distributed, mobile and fluid, adapting to sensory understanding of the underlying environment in which it operates. A proof-of concept mobile and ambient data access architecture is developed in order to further test the viability of such an approach. The paper concludes with an ontology engineering framework for systems of this type – named UBIS-ONTO
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing
Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but
limited bacterial killing by these cells. Co-colonization by Sp and a Gram-negative species, Haemophilus influenzae (Hi),
provides sufficient stimulus to induce neutrophil and complement-mediated clearance of Sp from the mucosal surface
in a murine model. Products from Hi, but not Sp, also promote killing of Sp by ex vivo neutrophil-enriched peritoneal
exudate cells. Here we identify the stimulus from Hi as its peptidoglycan. Enhancement of opsonophagocytic killing
was facilitated by signaling through nucleotide-binding oligomerization domain-1 (Nod1), which is involved in
recognition of γ-D-glutamyl-meso-diaminopimelic acid (meso-DAP) contained in cell walls of Hi but not Sp. Neutrophils
from mice treated with Hi or compounds containing meso-DAP, including synthetic peptidoglycan fragments, showed
increased Sp killing in a Nod1-dependent manner. Moreover, Nod1-/- mice showed reduced Hi-induced clearance of Sp
during co-colonization. These observations offer insight into mechanisms of microbial competition and demonstrate
the importance of Nod1 in neutrophil-mediated clearance of bacteria in vivo
Making GDPR Usable: A Model to Support Usability Evaluations of Privacy
We introduce a new model for evaluating privacy that builds on the criteria
proposed by the EuroPriSe certification scheme by adding usability criteria.
Our model is visually represented through a cube, called Usable Privacy Cube
(or UP Cube), where each of its three axes of variability captures,
respectively: rights of the data subjects, privacy principles, and usable
privacy criteria. We slightly reorganize the criteria of EuroPriSe to fit with
the UP Cube model, i.e., we show how EuroPriSe can be viewed as a combination
of only rights and principles, forming the two axes at the basis of our UP
Cube. In this way we also want to bring out two perspectives on privacy: that
of the data subjects and, respectively, that of the controllers/processors. We
define usable privacy criteria based on usability goals that we have extracted
from the whole text of the General Data Protection Regulation. The criteria are
designed to produce measurements of the level of usability with which the goals
are reached. Precisely, we measure effectiveness, efficiency, and satisfaction,
considering both the objective and the perceived usability outcomes, producing
measures of accuracy and completeness, of resource utilization (e.g., time,
effort, financial), and measures resulting from satisfaction scales. In the
long run, the UP Cube is meant to be the model behind a new certification
methodology capable of evaluating the usability of privacy, to the benefit of
common users. For industries, considering also the usability of privacy would
allow for greater business differentiation, beyond GDPR compliance.Comment: 41 pages, 2 figures, 1 table, and appendixe
Profiling and framing structures for pervasive information systems development
Pervasive computing is a research field of computing technology that aims to achieve a new computing paradigm. Software engineering has been, since its existence, subject of research and improvement in several areas of interest. Model-Based/Driven Development (MDD) constitutes an approach to software design and development that potentially contributes to: concepts closer to domain and reduction of semantic gaps; automation and less sensitivity to technological changes; capture of expert knowledge and reuse. This paper presents a profiling and framing structure approach for the development of Pervasive Information Systems (PIS). This profiling and framing structure allows the organization of the functionality that can be assigned to computational devices in a system and of the corresponding development structures and models, being. The proposed approach enables a structural approach to PIS development. The paper also presents a case study that allowed demonstrating the applicability of the approach.Fundação para a Ciência e a Tecnologia (FCT
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Evaluation of a large-scale donation of Lifebox pulse oximeters to non-physician anaesthetists in Uganda
Summary Pulse oximetry is widely accepted as essential monitoring for safe anaesthesia, yet is frequently unavailable in resource-limited settings. The Lifebox pulse oximeter, and associated management training programme, was delivered to 79 non-physician anaesthetists attending the 2011 Uganda Society of Anaesthesia Annual Conference. Using a standardised assessment, recipients were tested for their knowledge of oximetry use and hypoxia management before, immediately following and 3–5 months after the training. Before the course, the median (IQR [range]) test score for the anaesthetists was 36 (34–39 [26–44]) out of a maximum of 50 points. Immediately following the course, the test score increased to 41 (38–43 [25–47]); p < 0.0001 and at the follow-up visit at 3–5 months it was 41 (39–44 [33–49]); p = 0.001 compared with immediate post-training test scores, and 75/79 (95%) oximeters were in routine clinical use. This method of introduction resulted in a high rate of uptake of oximeters into clinical practice and a demonstrable retention of knowledge in a resource-limited setting
Magnetic string contribution to hadron dynamics in QCD
Dynamics of a light quark in the field of static source (heavy-light meson)
is studied using the nonlinear Dirac equation, derived recently. Special
attention is paid to the contribution of magnetic correlators and it is found
that it yields a significant increase of string tension at intermediate
distances. The spectrum of heavy-light mesons is computed with account of this
contribution and compared to experimental and lattice data.Comment: 10 pages Revte
Optically induced coherent intra-band dynamics in disordered semiconductors
On the basis of a tight-binding model for a strongly disordered semiconductor
with correlated conduction- and valence band disorder a new coherent dynamical
intra-band effect is analyzed. For systems that are excited by two, specially
designed ultrashort light-pulse sequences delayed by tau relatively to each
other echo-like phenomena are predicted to occur. In addition to the inter-band
photon echo which shows up at exactly t=2*tau relative to the first pulse, the
system responds with two spontaneous intra-band current pulses preceding and
following the appearance of the photon echo. The temporal splitting depends on
the electron-hole mass ratio. Calculating the population relaxation rate due to
Coulomb scattering, it is concluded that the predicted new dynamical effect
should be experimentally observable in an interacting and strongly disordered
system, such as the Quantum-Coulomb-Glass.Comment: to be published in Physical Review B15 February 200
Averages of b-hadron Properties at the End of 2005
This article reports world averages for measurements on b-hadron properties
obtained by the Heavy Flavor Averaging Group (HFAG) using the available results
as of at the end of 2005. In the averaging, the input parameters used in the
various analyses are adjusted (rescaled) to common values, and all known
correlations are taken into account. The averages include lifetimes, neutral
meson mixing parameters, parameters of semileptonic decays, branching fractions
of B meson decays to final states with open charm, charmonium and no charm, and
measurements related to CP asymmetries
Ten Years of Experience Training Non-Physician Anesthesia Providers in Haiti.
Surgery is increasingly recognized as an effective means of treating a proportion of the global burden of disease, especially in resource-limited countries. Often non-physicians, such as nurses, provide the majority of anesthesia; however, their training and formal supervision is often of low priority or even non-existent. To increase the number of safe anesthesia providers in Haiti, Médecins Sans Frontières has trained nurse anesthetists (NAs) for over 10 years. This article describes the challenges, outcomes, and future directions of this training program. From 1998 to 2008, 24 students graduated. Nineteen (79%) continue to work as NAs in Haiti and 5 (21%) have emigrated. In 2008, NAs were critical in providing anesthesia during a post-hurricane emergency where they performed 330 procedures. Mortality was 0.3% and not associated with lack of anesthesiologist supervision. The completion rate of this training program was high and the majority of graduates continue to work as nurse anesthetists in Haiti. Successful training requires a setting with a sufficient volume and diversity of operations, appropriate anesthesia equipment, a structured and comprehensive training program, and recognition of the training program by the national ministry of health and relevant professional bodies. Preliminary outcomes support findings elsewhere that NAs can be a safe and effective alternative where anesthesiologists are scarce. Training non-physician anesthetists is a feasible and important way to scale up surgical services resource limited settings
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