A Ball-Milling-Enabled Reformatsky Reaction

An operationally simple one‐jar one‐step mechanochemical Reformatsky reaction using in situ generated organozinc intermediates under neat grinding conditions has been developed. Notable features of this reaction protocol are that it requires no solvent, no inert gases, and no pre‐activation of the bulk zinc source. The developed process is demonstrated to have good substrate scope (39–82 % yield) and is effective irrespective of the initial morphology of the zinc source

Anion binding by multidentate Lewis acids: a DFT study

Density functional studies of model tribora-macrocyclic Lewis acids indicate extremely strong binding of the methyl anion, which in some cases exceeds that of B(C 6F 5) 3. In addition anion selectivity for the fluoride ion is implied by binding energies ca. 200 kJ mol -1 greater than those of other halides

Hydrogen-bonding motifs in the solid-state structure of ferroceneboronic acid

At 180 K, the crystal structure of ferroceneboronic acid, [Fe(C 5H5)(C5H6BO2)], consists of centrosymmetric [FcB(OH)2]2 dimers [Fc is (η5-C5H5)Fe(η5-C 5H4)], formed by a pair of complementary O-H⋯O hydrogen-bonding interactions [O⋯H 1.97 Å and O⋯O 2.806 (3) Å]. The remaining two O-bound H atoms per [FcB(OH)2] 2 moiety serve to link the dimeric units to adjacent dimers in a criss-cross fashion, very similar to that between hydrogen-bonded chains in solid Fe[η5-C5H4B(OH)2] 2. © 2004 International Union of Crystallography Printed in Great Britain - all rights reserved

Selective electrochemical detection of hydrogen fluoride by ambiphilic ferrocene derivatives.

(Graph Presented) Appropriate linking of Lewis acidic and Lewis basic components - in this case boronic acid and tertiary amine functionalities - allows the construction of a robust organometallic receptor capable of selectively binding hydrogen fluoride. This system can differentiate between exposure to HF and to related acids, such as HCl, by providing opposing electrochemical responses (see picture). © 2005 Wiley-VCH Verlag GmbH and Co. KGaA