Dilatonic Inflation and SUSY Breaking in String-inspired Supergravity

The theory of inflation will be investigated as well as supersymmetry breaking in the context of supergravity, incorporating the target-space duality and the nonperturbative gaugino condensation in the hidden sector. We found an inflationary trajectory of a dilaton field and a condensate field which breaks supersymmetry at once. The model satisfies the slow-roll condition which solves the eta-problem. When the particle rolls down along the minimized trajectory of the potential V(S,Y) at a duality invariant point of T=1, we can obtain the e-fold value \sim 57. And then the cosmological parameters obtained from our model well match the recent WMAP data combined with other experiments. This observation suggests one to consider the string-inspired supergravity as a fundamental theory of the evolution of the universe as well as the particle theory.Comment: 10 pages, 4 eps figures. Typos and references corrected. Final version to appear in Mod. Phys. Lett.

Neutrino Mass Textures with Maximal CP Violation

We have found three types of neutrino mass textures, which give maximal CP-violation as well as maximal atmospheric neutrino mixing. These textures are described by six real mass parameters: one specified by two complex flavor neutrino masses and two constrained ones and the others specified by three complex flavor neutrino masses. In each texture, we calculate mixing angles and masses as well as Majorana CP phases.Comment: 10 pages, RevTex, no figures, references updated, version to appear in Phys. Rev.

Determination of Neutrino Mass Texture for Maximal CP Violation

We show a general form of neutrino mass matrix (M), whose matrix elements are denoted by M_{ij} (i.j=e, mu, tau) as flavor neutrino masses, that induces maximal CP violation as well as maximal atmospheric neutrino mixing. The masses of M_{mu mu}, M_{tau tau} and M_{mu tau}+sigma M_{ee} (sigma =\pm 1) turn out to be completely determined by M_{e mu} and M_{e tau} for given mixing angles. The appearance of CP violation is found to originate from the interference between the mu-tau symmetric part of M and its breaking part. If |M_{e mu}|=|M_{e tau}|, giving either M_{e mu}=-sigma e^{i theta} M_{e tau} or M_{e mu}=-sigma e^{i theta}M*_{e tau} with a phase parameter theta, is further imposed, we find that |M_{mu mu}|=|M_{tau tau}|is also satisfied. These two constraints can be regarded as an extended version of the constraints in the mu-tau symmetric texture given by M_{e mu}=-sigma M_{e tau} and M_{mu mu}=M_{tau tau}. Majorana CP violation becomes active if arg(M_{mu tau})\neq arg(M_{e mu})+theta/2 for M_{e mu}=-sigma e^{i theta} M_{e tau} and if arg(M_{mu tau})\neq theta/2 for M_{e mu}=-sigma e^{i theta} M*_{e tau}.Comment: 10 pages, RevTex, typos corrected, minor clarifications added in Sec.3 and Sec.4, version to appear in Nucl. Phys.

Preparation and Observation of Fresh-frozen Sections of the Green Fluorescent Protein Transgenic Mouse Head

Hard tissue decalcification can cause variation in the constituent protein characteristics. This paper describes a method of preparating of frozen mouse head sections so as to clearly observe the nature of the constituent proteins. Frozen sections of various green fluorescent protein (GFP) transgenic mouse heads were prepared using the film method developed by Kawamoto and Shimizu. This method made specimen dissection without decalcification possible, wherein GFP was clearly observed in an undamaged state. Conversely, using the same method with decalcification made GFP observation in the transgenic mouse head difficult. This new method is suitable for observing GFP marked cells, enabling us to follow the transplanted GFP marked cells within frozen head sections

Modification of the Network-MT method and its first application in imaging the deep conductivity structure beneath the Kii Peninsula, southwestern Japan

Abstract The Network-Magnetotelluric (NMT) method is well-suited for investigating deep and large-scale conductivity structure; however, application of the method is strongly dependent on the availability of telecommunication facilities (specifically, metallic transmission cables). To overcome the problem posed by the progressive replacement of metallic transmission cables with fiber cables, we developed a modified NMT (modified NMT) method consisting of purpose-built electrodes, making use of local metallic telecommunication lines, without a transmission cable. We first applied this modified NMT method over the Kii Peninsula, southwestern Japan, undertaking two-dimensional conductivity modeling along a transect across the central part of the peninsula. The model is characterized by a large (∼20 km wide and depths of 10–60 km) and highly conductive (&lt; 10 Ω m) zone in the central part of the peninsula between the Conrad discontinuity and the upper surface of the Philippine Sea slab. This zone contains the hypocenters of many deep low-frequency tremors but regular earthquakes are rare. The zone also corresponds to a high-V p /V s area. The presence of fluid in the zone plays a key role in the absence of regular earthquakes, occurrence of deep low-frequency tremors, and elevated V p /V s values, as well as enhancing conductivity.</jats:p

Erythroid cells play essential roles in angiogenesis by bone marrow cell implantation

Bone marrow cell implantation (BMI) has been utilized to treat patients with limb and heart ischemia. BMI provides angiogenic precursors and angiogenic cytokine-producing cells, especially erythroid cells. In this study, we induced in vitro angiogenesis cultures and in vivo BMI simulation using a murine limb ischemia model to examine the role of erythroid cells and the effect of erythropoietin (EPO). Human erythroid colonies (BFU-e) induced capillary networks around the colonies in vitro. Erythroid cells in human bone marrow produced vascular endothelial growth factor and placental growth factor. The angiogenic effects of erythroid cells were further amplified in the presence of EPO. Limb-ischemic mice were treated with BMI ± EPO, and limb survival, blood flow recovery, and muscle histology were analyzed. Treatment with whole bone marrow cells + EPO significantly improved limb survival and blood flow. The cumulative effects of EPO on BMI induced and increase in capillary number and artery enlargement. Erythroid cells were essential for the in vivo effects of BMI, and CD14-positive cells supported the biological effects. In addition to the direct effect of EPO on angiogenesis, EPO showed indirect effect on angiogenesis through amplifying the angiogenic effects by erythroid cells supported by CD14-positive cells.journal articl

Randomized phase 2 study of perampanel for sporadic amyotrophic lateral sclerosis

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