Persistence of two genotypes of Neisseria gonorrhoeae during transmission.

Isolates of Neisseria gonorrhoeae were tested using a highly discriminatory typing method, opa typing, to examine the genetic diversity over a 2-year study period of isolates from all consecutive patients with gonorrhea attending the Genitourinary Medicine clinic in Sheffield, United Kingdom. Two opa genotypes were detected throughout the 2-year time period and comprised 41% of all strains tested. The persistence of two opa types was investigated further to determine the apparent genetic stability, by examining the ability of isolates to undergo intragenic and intergenic recombination and mutation in vitro. Intragenic recombination or mutation involving the opa genes of N. gonorrhoeae in the selected isolates was not detected, but intergenic recombination did occur. opa genes of N. gonorrhoeae in vivo appear to diversify primarily through intergenic recombination. Intergenic recombination in vivo would require the presence of a mixed gonococcal infection, in which an individual is concurrently colonized with more than one strain of N. gonorrhoeae. We propose that the level of diversity of opa genotypes in a population is linked to the degree of sexual mixing of individuals and the incidence of mixed infections of N. gonorrhoeae

State-Business Relations and Investment in Egypt

This study shows that informal relationships between key policymakers and investors have played an important role in raising levels of investment and fostering economic growth. Comparative observations show that common social roots and common professional background facilitate the emergence of an effective public-private growth alliance but the only necessary conditions are common interest and common understanding of the problems to be solved. The comparative research on two old and two new sectors shows in detail how informal relationships have emerged and how they have made an impact but it warns against overstating their investment-enhancing role. Effective relationships between policymakers and investors – abbreviated to CIPI – are not the direct cause of increases in investment but can play a critical role in unleashing the profit potential of specific sectors. Research on the food industry shows how CIPI helped to overcome supply constraints and political obstacles in decision-making. Research on the communications industry shows how CIPI helped Egypt to overcome initial barriers to entry and establish a new industry virtually from scratch. While the gains were sometimes appropriated by a few actors, the research shows that exclusive relationships can have inclusive effects, depending on how the private sector is organised. Quantitative examination of whether CIPI had an enduring investment-enhancing effect was inconclusive. There is no doubt however that the CIPI was an effective transitional arrangement. It helped investors to overcome barriers to economic growth, it helped policymakers to overcome deficiencies in their own government agencies and it helped both sides to work together in establishing new sectorspecific rules and improving the general regulatory framework. The general lesson from this research is that such transitional arrangements deserve more attention, both to gain a better understanding of the political economy of investment and growth and to make research more relevant for policy

El sentido de la muerte para el afrodescendiente de San Pablo, norte vida y esperanza

Teólogo (a)Pregrad

Iniciación cristiana en la parroquia "Nuestra Señora de la Consolata", una exigencia de la nueva evangelización

"La iniciación Cristiana ha sido entendida como la preparación que se hace para que uno reciba los sacramentos de Bautismo, confirmación y Eucaristía. Este trabajo quiere dar otra mirada a la misma iniciación, no solamente como la catequesis a los niños para que sean bautizados, sino también como el proceso que se ha de realizar para que los iniciados puedan llegar a la madurez de la fe. A partir de una experiencia vivida en la parroquia ""Nuestra Señora de la Consolata"" que está ubicada en ""El Vergel"" - Bogotá, y según la observación y entrevistas hechas, uno se da cuenta que después de las celebraciones de los sacramentos, la mayoría de los bautizados no se encuentran más. La Iglesia hoy propone una catequesis permanente, que lleve al compromiso en el servicio a la Iglesia y a la sociedad."Teólogo (a)Pregrad

INFLUÊNCIA DO TEMPO E DA TEMPERATURA DE ARMAZENAMENTO NA CONTAGEM BACTERIANA TOTAL E NO TEOR DE SÓLIDOS DO LEITE CRU REFRIGERADO

O leite é um dos produtos que mais contribuíram para a economia brasileira e apresenta alto valor nutritivo, composto por 87% de água e 13% de sólidos como gordura, proteína, lactose, sais minerais e vitaminas. Por possuir tantos nutrientes ele se torna um ótimo meio de cultura para microrganismos, o que pode acarretar em prejuízos tanto para a indústria como para o consumidor, sendo assim é de suma importância garantir a sua qualidade. Uma das formas de avaliar a qualidade do leite cru refrigerado é observando a contagem bacteriana total (CBT) ou contagem padrão em placa (CPP). A CBT pode ser influenciada por diversos fatores, dentre eles o tempo e a temperatura de armazenamento do leite. Nesse contexto, o presente trabalho objetivou verificar como a temperatura e o tempo de armazenamento podem influenciar na contagem bacteriana total e no teor de sólidos do leite cru refrigerado. O trabalho foi realizado a partir da coleta de 6 amostras de leite recém ordenhado em uma fazenda localizada em Granada, distrito de Abre Campo – MG, e analisadas num período de 48 horas no Laboratório do Hospital Veterinário Gardingo. As amostras apresentaram crescente aumento na contagem padrão em placa desde a primeira análise após a coleta do leite, mesmo com a temperatura de armazenamento dentro do limite estabelecido pela legislação e relativa homogeneidade nos teores de sólidos

Overview of biologically digested leachate treatment using adsorption

Biological process is effective in treating most biodegradable organic matter present in leachate; however, a significant amount of ammonia, metals and refractory organic compounds may still remain in this biologically digested leachate. This effluent cannot be released to receiving bodies until the discharge limit is met. Several physical/chemical processes have been practiced as post-treatment to remove the remaining pollutants including coagulation–flocculation, oxidation and adsorption. Adsorption is often applied in leachate treatment as it enhances removal of refractory organic compounds. This chapter will focus on works related to adsorption as one of the commonly used methods to treat biologically digested leachate further down to acceptable discharge limit

Overview of biologically digested leachate treatment using adsorption

Biological process is effective in treating most biodegradable organic matter present in leachate; however, a significant amount of ammonia, metals and refractory organic compounds may still remain in this biologically digested leachate. This effluent cannot be released to receiving bodies until the discharge limit is met. Several physical/chemical processes have been practiced as post-treatment to remove the remaining pollutants including coagulation–flocculation, oxidation and adsorption. Adsorption is often applied in leachate treatment as it enhances removal of refractory organic compounds. This chapter will focus on works related to adsorption as one of the commonly used methods to treat biologically digested leachate further down to acceptable discharge limit

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Universidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento Dermatologia e RadioterapiaUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento Dermatologia e Radioterapi

Risk factors for hospitalisation and death from COVID-19: a prospective cohort study in South Sudan and Eastern Democratic Republic of the Congo.

Objectives: Our study described demographic characteristics, exposures and symptoms, and comorbidities to evaluate risk factors of hospitalisation and mortality among cases in Juba, South Sudan (SSD) and North and South Kivu in eastern Democratic Republic of the Congo (DRC). Design: Prospective observational cohort of COVID-19 cases.MethodsIndividuals presenting for care at one of five study facilities in SSD (n=1) or DRC (n=4) or referred from home-based care by mobile medical teams between December 2020 and June 2021 were eligible for enrolment. Demographic characteristics, COVID-19 exposures, symptoms at presentation, as well as acute and chronic comorbidities, were evaluated using a standard questionnaire at enrolment. Disease progression was characterised by location of care using mixed-effects regression models. Results: 751 individuals were eligible for enrolment. Among cases followed to discharge or death (n=519), 375 were enrolled outpatients (75.7%). A similar number of cases were enrolled in DRC (n=262) and SSD (n=257). Overall mortality was 4.8% (95% CI: 3.2% to 6.9%); there were no outpatient deaths. Patients presenting with any symptoms had higher odds of hospitalisation (adjusted OR (AOR) 2.78, 95% CI 1.47 to 5.27) and all deaths occurred among symptomatic individuals. Odds of both hospitalisation and mortality were greatest among cases with respiratory symptoms; presence of low oxygen levels on enrolment was strongly associated with both hospitalisation (AOR 7.77, 95% CI 4.22 to 14.29) and mortality (AOR 25.29, 95% CI 6.42 to 99.54). Presence of more than one chronic comorbidity was associated with 4.96 (95% CI 1.51 to 16.31) times greater odds of death; neither infectious comorbidities evaluated, nor malnutrition, were significantly associated with increased mortality. Conclusions: Consistent with prior literature, older age, low oxygen level, other respiratory symptoms and chronic comorbidities were all risk factors for mortality. Patients presenting with these characteristics were more likely to be hospitalised, providing evidence of effective triage and referral. Trial registration number: NCT04568499