Induced cosmological constant and other features of asymmetric brane embedding

We investigate the cosmological properties of an "induced gravity" brane scenario in the absence of mirror symmetry with respect to the brane. We find that brane evolution can proceed along one of four distinct branches. By contrast, when mirror symmetry is imposed, only two branches exist, one of which represents the self-accelerating brane, while the other is the so-called normal branch. This model incorporates many of the well-known possibilities of brane cosmology including phantom acceleration (w < -1), self-acceleration, transient acceleration, quiescent singularities, and cosmic mimicry. Significantly, the absence of mirror symmetry also provides an interesting way of inducing a sufficiently small cosmological constant on the brane. A small (positive) Lambda-term in this case is induced by a small asymmetry in the values of bulk fundamental constants on the two sides of the brane.Comment: 17 pages, 4 figures. New results and two figures discussing transient acceleration are included. Version accepted for publication in JCA

Cosmology of intersecting brane world models in Gauss-Bonnet gravity

We study the cosmological properties of a codimension two brane world that sits at the intersection between two four branes, in the framework of six dimensional Einstein-Gauss-Bonnet gravity. Due to contributions of the Gauss-Bonnet terms, the junction conditions require the presence of localized energy density on the codimension two defect. The induced metric on this surface assumes a FRW form, with a scale factor associated to the position of the brane in the background; we can embed on the codimension two defect the preferred form of energy density. We present the cosmological evolution equations for the three brane, showing that, for the case of pure AdS$_6$ backgrounds, they acquire the same form of the ones for the Randall-Sundrum II model. When the background is different from pure AdS$_6$, the cosmological behavior is potentially modified in respect to the typical one of codimension one brane worlds. We discuss, in a particular model embedded in an AdS$_6$ black hole, the conditions one should satisfy in order to obtain standard cosmology at late epochs.Comment: 19 pages, no figures, JHEP style. v2: Typos corrected and references adde

Disappearing Dark Matter in Brane World Cosmology: New Limits on Noncompact Extra Dimensions

We explore cosmological implications of dark matter as massive particles trapped on a brane embedded in a Randall-Sundrum noncompact higher dimension $AdS_5$ space. It is an unavoidable consequence of this cosmology that massive particles are metastable and can disappear into the bulk dimension. Here, we show that a massive dark matter particle (e.g. the lightest supersymmetric particle) is likely to have the shortest lifetime for disappearing into the bulk. We examine cosmological constraints on this new paradigm and show that disappearing dark matter is consistent (at the 95% confidence level) with all cosmological constraints, i.e. present observations of Type Ia supernovae at the highest redshift, trends in the mass-to-light ratios of galaxy clusters with redshift, the fraction of X-ray emitting gas in rich clusters, and the spectrum of power fluctuations in the cosmic microwave background. A best $2 \sigma$ concordance region is identified corresponding to a mean lifetime for dark matter disappearance of $15 \le \Gamma^{-1} \le 80$ Gyr. The implication of these results for brane-world physics is discussed.Comment: 7 pages, 7 figures, new cosmological constraints added, accepted for publication in PR

Manifestations of String Theory in Astrophysical Data and at the LHC

With the advent of the LHC and the continuing influx of cosmological data, phenomenological aspects of string theory have received renewed attention in recent years and many problems have been properly incorporated in this framework. In this Dissertation, we suggest new string-related candidates for the origin of dark energy and dark matter and propose ways of searching for string resonances at the LHC.Comment: Ph. D. Thesis, University of Wisconsin-Milwaukee, August 200

Brane-bulk matter relation for a purely conical codimension-2 brane world

We study gravity on an infinitely thin codimension-2 brane world, with purely conical singularities and in the presence of an induced gravity term on the brane. We show that in this approximation, the energy momentum tensor of the bulk is strongly related to the energy momentum tensor of the brane and thus the gravity dynamics on the brane are induced by the bulk content. This is in contrast with the gravity dynamics on a codimension-1 brane. We show how this strong result is relaxed after including a Gauss-Bonnet term in the bulk.Comment: 12 pages, mistake corrected, references adde

Mycobacterium tuberculosis antigen 85B and ESAT-6 expressed as a recombinant fusion protein in Mycobacterium smegmatis elicits cell-mediated immune response in a murine vaccination model

This is the post-print version of the final paper published in Molecular Immunology. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2012 Elsevier B.V.In this study, we investigated the potential molecular and immunological differences of a recombinant fusion protein (Hybrid-1), comprising of the immunodominant antigens Ag85B and ESAT-6 from Mycobacterium tuberculosis, derived from two different expression systems, namely Mycobacterium smegmatis and Escherichia coli. The fusion protein was successfully expressed and purified from both bacterial hosts and analyzed for any host-dependent post-translational modifications that might affect the immunogenicity of the protein. We investigated the immunogenicity of Hybrid-1 expressed in the two host species in a murine vaccination model, together with a reference standard Hybrid-1 (expressed in E. coli) from the Statens Serum Institut. No evidence of any post-translation modification was found in the M. smegmatis-derived Hybrid-1 fusion protein, nor were there any significant differences in the T-cell responses obtained to the three antigens analyzed. In conclusion, the Hybrid-1 fusion protein was successfully expressed in a homologous expression system using M. smegmatis and this system is worth considering as a primary source for vaccination trials, as it provided protein of excellent yield, stability and free from lipopolysaccharide.European TB-VAC consortium and Brunel University

Hybrid compactifications and brane gravity in six dimensions

We consider a six-dimensional axisymmetric Einstein-Maxwell model of warped braneworlds. The bulk is bounded by two branes, one of which is a conical 3-brane and the other is a 4-brane wrapped around the axis of symmetry. The latter brane is assumed to be our universe. If the tension of the 3-brane is fine-tuned, it folds the internal two-dimensional space in a narrow cone, making sufficiently small the Kaluza-Klein circle of the 4-brane. An arbitrary energy-momentum tensor can be accommodated on this ring-like 4-brane. We study linear perturbations sourced by matter on the brane, and show that weak gravity is apparently described by a four-dimensional scalar-tensor theory. The extra scalar degree of freedom can be interpreted as the fluctuation of the internal space volume (or that of the circumference of the ring), the effect of which turns out to be suppressed at long distances. Consequently, four-dimensional Einstein gravity is reproduced on the brane. We point out that as in the Randall-Sundrum model, the brane bending mode is crucial for recovering the four-dimensional tensor structure in this setup.Comment: 15 pages, 2 figures; v2: references added; v3: accepted for publication in Class. Quant. Gra

On Bouncing Brane-Worlds, S-branes and Branonium Cosmology

We present several higher-dimensional spacetimes for which observers living on 3-branes experience an induced metric which bounces. The classes of examples include boundary branes on generalised S-brane backgrounds and probe branes in D-brane/anti D-brane systems. The bounces we consider normally would be expected to require an energy density which violates the weak energy condition, and for our co-dimension one examples this is attributable to bulk curvature terms in the effective Friedmann equation. We examine the features of the acceleration which provides the bounce, including in some cases the existence of positive acceleration without event horizons, and we give a geometrical interpretation for it. We discuss the stability of the solutions from the point of view of both the brane and the bulk. Some of our examples appear to be stable from the bulk point of view, suggesting the possible existence of stable bouncing cosmologies within the brane-world framework.Comment: 35 pages, 7 figures, JHEP style. Title changed and references adde

Brane cosmological solutions in six-dimensional warped flux compactifications

We study cosmology on a conical brane in the six-dimensional Einstein-Maxwell-dilaton system, where the extra dimensions are compactified by a magnetic flux. We systematically construct exact cosmological solutions using the fact that the system is equivalently described by (6+n)-dimensional pure Einstein-Maxwell theory via dimensional reduction. In particular, we find a power-law inflationary solution for a general dilatonic coupling. When the dilatonic coupling is given by that of Nishino-Sezgin chiral supergravity, this reduces to the known solution which is not inflating. The power-law solution is shown to be the late-time attractor. We also investigate cosmological tensor perturbations in this model using the (6+n)-dimensional description. We obtain the separable equation of motion and find that there always exist a zero mode, while tachyonic modes are absent in the spectrum. The mass spectrum of Kaluza-Klein modes is obtained numerically.Comment: 12 pages, 2 figures; v2: references added; v3: version published in JCA