Effect of Annona Formulations on Non-target Invertebrates and on Physicochemical Water Parameters at Semi-field Condition

Plant extracts from the genus Annona exhibit insecticidal properties and thus, may offer an alternative to synthetic insecticides. In the present study larvicidal efficacy of formulations of Annona squamosa and A. montana were evaluated against Anopheline and Culicine larvae in the laboratory and semi-field conditions. In the laboratory there was no significant difference (t=0.5313, p>0.05) in the effectiveness of the A. squamosa formulation at 50 μg/ml and above between An. gambiae and Culex quinquefasciatus by day 4. Significant difference (t= 2.649, p<0.05) was observed for A. montana formulation at higher concentration than 50 μg/ml since An. gambiae was more susceptible than Cx. quinquefasciatus. In semi-field condition the efficacy of the two formulations against Anopheline was not quite significant (t= 2.504, p>0.05). The activity of A. montana leaf powder against Culicines was significantly lower compared to A. squamosal (t=3.827, P<0.05). The variation in water parameters had no significant effect on the efficacy of the formulations. The formulations did not affect the survival of the 9 invertebrate groups tested during the period of study except for the Order Ephemeroptera (Mayflies) whose mortalities was more than 85%. The\ud formulations have proven to offer an alternative to synthetic insecticides

Religious Vehicle Stickers in Nigeria: a discourse of identity, faith and social vision

This study focuses on analysing the ways in which vehicle stickers construct individual and group identities, people’s religious faith and social vision in the context of religious assumptions and practices in Nigeria. Data comprise 73 vehicle stickers collected in Lagos and Ota, between 2006 and 2007 and are analysed within the framework of the post-structuralist model of discourse analysis which views discourse as a product of a complex system of social and institutional practices that sustain its continuous existence (Derrida, 1982; Fairclough, 1989, 1992, 1995; Foucault, 1972, 1981). Results show that through stickers people define their individual and group identities within religious institutional practices. And as a means of group identification, they guarantee social security and privileges. In constructing social vision the stickers help mould the individual aspiration about a future which transcends the present. Significantly, stickers in the data also reveal the tension between Islam and Christianity and the struggle to propagate one above the other. KEY WORDS: assumption, discourse, discursive, practices, religion, stickers

Combining Slaughterhouse Surveillance Data with Cattle Tracing Scheme and Environmental Data to Quantify Environmental Risk Factors for Liver Fluke in Cattle.

Liver fluke infection causes serious disease (fasciolosis) in cattle and sheep in many regions of the world, resulting in production losses and additional economic consequences due to condemnation of the liver at slaughter. Liver fluke depends on mud snails as an intermediate host and infect livestock when ingested through grazing. Therefore, environmental factors play important roles in infection risk and climate change is likely to modify this. Here, we demonstrate how slaughterhouse data can be integrated with other data, including animal movement and climate variables to identify environmental risk factors for liver fluke in cattle in Scotland. We fitted a generalized linear mixed model to the data, with exposure-weighted random and fixed effects, an approach which takes into account the amount of time cattle spent at different locations, exposed to different levels of risk. This enabled us to identify an increased risk of liver fluke with increased animal age, rainfall, and temperature and for farms located further to the West, in excess of the risk associated with a warmer, wetter climate. This model explained 45% of the variability in liver fluke between farms, suggesting that the unexplained 55% was due to factors not included in the model, such as differences in on-farm management and presence of wet habitats. This approach demonstrates the value of statistically integrating routinely recorded slaughterhouse data with other pre-existing data, creating a powerful approach to quantify disease risks in production animals. Furthermore, this approach can be used to better quantify the impact of projected climate change on liver fluke risk for future studies

Reversal of loss of bone mass in old mice treated with mefloquine

Aging is accompanied by imbalanced bone remodeling, elevated osteocyte apoptosis, and decreased bone mass and mechanical properties; and improved pharmacologic approaches to counteract bone deterioration with aging are needed. We examined herein the effect of mefloquine, a drug used to treat malaria and systemic lupus erythematosus and shown to ameliorate bone loss in glucocorticoid-treated patients, on bone mass and mechanical properties in young and old mice. Young 3.5-month-old and old 21-month-old female C57BL/6 mice received daily injections of 5 mg/kg/day mefloquine for 14 days. Aging resulted in the expected changes in bone volume and mechanical properties. In old mice mefloquine administration reversed the lower vertebral cancellous bone volume and bone formation; and had modest effects on cortical bone volume, thickness, and moment of inertia. Mefloquine administration did not change the levels of the circulating bone formation markers P1NP or alkaline phosphatase, whereas levels of the resorption marker CTX showed trends towards increase with mefloquine treatment. In addition, and as expected, aging bones exhibited an accumulation of active caspase3-expressing osteocytes and higher expression of apoptosis-related genes compared to young mice, which were not altered by mefloquine administration at either age. In young animals, mefloquine induced higher periosteal bone formation, but lower endocortical bone formation. Further, osteoclast numbers were higher on the endocortical bone surface and circulating CTX levels were increased, in mefloquine- compared to vehicle-treated young mice. Consistent with this, addition of mefloquine to bone marrow cells isolated from young mice led to increased osteoclastic gene expression and a tendency towards increased osteoclast numbers in vitro. Taken together our findings identify the age and bone-site specific skeletal effects of mefloquine. Further, our results highlight a beneficial effect of mefloquine administration on vertebral cancellous bone mass in old animals, raising the possibility of using this pharmacologic inhibitor to preserve skeletal health with aging

Gender and Language Acquisition

Opinions have been divergent concerning the rate of language acquisition between male and female learners. This paper examined the claims that male learners acquire language better and faster than their female counterparts using phonology of English as a unit of language study. The scores of forty students (twenty males and twenty females) of the Federal College of Education Yola in phonology-related courses were examined. One research question and a null hypothesis were posed. A t-test of the scores gave a verdict of no significant difference in the mean scores of the two groups. The study recommended that equal educational opportunities should be provided to all students irrespective of their gender differences

Larvicidal activities of five Kotschya species against Culex quinquefasciatus Say (Culicidae: Diptera)

Resistance of mosquito vectors to the commonly used chemical insecticides is posing threats to human health. It is becoming necessary to identify safe, eco-friendly and effective alternative sources of larvicides in order to reduce mosquito menace. HPLC profiling of the chemical constituents in the stem and root bark ethanol extracts had similar pattern of chemical constituents except for K. aeschynomenoides which indicated to have large quantity of polar compounds compared to others. In this study, the ethanolic extracts and powders of five Kotschya species were tested against Culex quinquefasciatus Say. Chemical profiling of the stem and root bark ethanol extracts from K. speciosa, K. thymodora, K. platyphylla, K. aeschynomenoides and K. strigosa did not show any major differences in terms of their chemical composition. At 0.5 mg/ml, the root and stem ethanol extracts from K. speciosa, K. thymodora and K. strigosa exhibited high larvicidal activity (&#8805; 70%) on the 8th day post treatment. Stem powder of K. thymodora and root powder of K. speciosa and K. strigosa had activity comparable to their respective extracts at 0.2% w/v and 0.4% w/v at the same exposure time. This suggests that Kotschya species contain same or related compounds in varying quantities that are responsible for larvicidal activity.Keywords: Fabaceae, Kotschya strigosa, K. speciosa, K. thymodora, K. platyphylla, K. aeschynomenoides, Larvicidal, Culex quinquefasciatu

Geospatial Analysis of Flood Problems in Jimeta Riverine Community of Adamawa State, Nigeria

Floods are among the most devastating natural disasters in the world, claiming more lives and causing more property damages than any other natural phenomena. In recent times, the incidence of flooding across Nigeria has left both the government and the governed devastated. It is no longer news that flooding and its attendant consequences are injurious to man while the spatial dimensions are often not mapped. This study, therefore, examined the nature of water level/extent and vulnerability in the riverine community of Jimeta, Adamawa State. Using time series analysis, four epoch satellite images covering the study area was used to evaluate the geospatial coverage of water along the watercourse of Upper Benue bordering the study area. Using ILWIS 3.8, ArcGIS 10.1 and statistical analysis, the spatial extent and vulnerability of settlements was mapped. Highly vulnerable (50m buffer) were differentiated from low risk zones (100m buffers). Study revealed that besides rainfall, excess water from Cameroun dam is largely responsible for the identified high level of inundation.  The impacts of flood on the local people are devastating as lives and properties have been lost while economic activities reduced due to health risks and mass migration to neighbouring villages and towns. Early flood warning system (EFWS), rapid response mechanism and outfit, strict adherence to zoning and building principles, evacuation of waste and maintenance of drainage systems, mass awareness campaign on flooding and other environmental hazards and, continuous rehabilitation and assistance of victims as a government, individual and NGOs are recommended hence synergy among stake holders is advocated. Keywords: Flood, GIS Buffer, Settlement, Vulnerability, Water Coverage