1,784 research outputs found
Large-scale structure formation for power spectra with broken scale invariance
We have simulated the formation of large-scale structure arising from
COBE-normalized spectra computed by convolving a primordial double-inflation
perturbation spectrum with the CDM transfer function. Due to the broken scale
invariance ('BSI') characterizing the primordial perturbation spectrum, this
model has less small-scale power than the (COBE-normalized) standard CDM model.
The particle-mesh code (with cells and particles) includes a
model for thermodynamic evolution of baryons in addition to the usual
gravitational dynamics of dark matter. It provides an estimate of the local gas
temperature. In particular, our galaxy-finding procedure seeks peaks in the
distribution of gas that has cooled. It exploits the fact that ``cold"
particles trace visible matter better than average and thus provides a natural
biasing mechanism. The basic picture of large-scale structure formation in the
BSI model is the familiar hierarchical clustering scenario. We obtain particle
in cell statistics, the galaxy correlation function, the cluster abundance and
the cluster-cluster correlation function and statistics for large and small
scale velocity fields. We also report here on a semi-quantitative study of the
distribution of gas in different temperature ranges. Based on confrontation
with observations and comparison with standard CDM, we conclude that the BSI
scenario could represent a promising modification of the CDM picture capable of
describing many details of large-scale structure formation.Comment: 15 pages, Latex using mn.sty, uuencoded compressed ps-file with 15
figures by anonymous ftp to ftp://ftp.aip.de/incoming/mueller/bsi.u
Dissipation of Magnetohydrodynamic Waves on Energetic Particles: Impact on Interstellar Turbulence and Cosmic Ray Transport
The physical processes involved in diffusion of Galactic cosmic rays in the
interstellar medium are addressed. We study the possibility that the nonlinear
MHD cascade sets the power-law spectrum of turbulence which scatters charged
energetic particles. We find that the dissipation of waves due to the resonant
interaction with cosmic ray particles may terminate the Kraichnan-type cascade
below wavelengths 10^13 cm. The effect of this wave dissipation has been
incorporated in the GALPROP numerical propagation code in order to asses the
impact on measurable astrophysical data. The energy-dependence of the
cosmic-ray diffusion coefficient found in the resulting self-consistent model
may explain the peaks in the secondary to primary nuclei ratios observed at
about 1 GeV/nucleon.Comment: 15 pages, 20 figures, 1 table, emulateapj.cls; To be published in ApJ
10 May 2006, v.64
Chiral Fermions on the Lattice
A recently proposed method for regularizing chiral gauge theories
non-perturbatively is discussed in detail. The result is an effective action
which can be computed from the lattice gauge field, and which is suited for
numerical simulations.Comment: Talk given by G. Schierholz at Yukawa International Seminar on
Non-Perturbative QCD: Structure of the QCD Vacuum (YKIS97), Kyoto, December
1997; typos correcte
Discovery of GeV Emission from the Circinus galaxy with the Fermi-LAT
We report the discovery of gamma-ray emission from the Circinus galaxy using
the Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope.
Circinus is a nearby (~4 Mpc) starburst with a heavily obscured Seyfert-type
active nucleus, bipolar radio lobes perpendicular to the spiral disk, and
kpc-scale jet-like structures. Our analysis of 0.1-100 GeV events collected
during 4 years of LAT observations reveals a significant (~ 7.3 sigma) excess
above the background. We find no indications of variability or spatial
extension beyond the LAT point-spread function. A power-law model used to
describe the 0.1-100 GeV gamma-ray spectrum yields a flux of
(18.8+/-5.8)x10^{-9} ph cm^{-2} s^{-1} and photon index 2.19+/-0.12,
corresponding to an isotropic gamma-ray luminosity of 3 x 10^{40} erg s^{-1}.
This observed gamma-ray luminosity exceeds the luminosity expected from
cosmic-ray interactions in the interstellar medium and inverse Compton
radiation from the radio lobes. Thus the origin of the GeV excess requires
further investigation.Comment: 7 pages, 7 figures, accepted for publication in the Astrophysical
Journa
Salinization dynamics in irrigated soils of the Svetloyarsk irrigation system, Volgograd oblast
On the basis of soil surveys performed by the Volgograd hydrogeological reclamation expedition in 1998 and 2006, published data, and original materials obtained by the authors, the dynamics of soil salinization within the Svetloyarsk irrigation system in Volgograd oblast during the irrigation and post-irrigation periods have been traced. It is found that high irrigation rates under conditions of poor drainage and closed drainage basins upon both shallow (within the Caspian Lowland) and relatively deep (on the Ergeni Upland) occurrence of saline groundwater and the presence of natural salts in the soils and subsoils lead to the rise in the groundwater level above the critical level and the development of secondary salinization in the previously surfacesaline, deeply saline, and even nonsaline soils. During the post-irrigation period (15-18 years) under modern climatic conditions, the groundwater level has been descending to a depth of more than 3 m, and the degree of salinity in the upper meter of light chestnut and meadow-chestnut soils has decreased owing to the leaching of salts with atmospheric precipitation
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons
Functional as well as structural alterations in mitochondria size, shape and distribution are precipitating, early events in progression of Alzheimer's Disease (AD). We reported that a 20\u201322 kDa NH2-tau fragment (aka NH2htau), mapping between 26 and 230 amino acids of the longest human tau isoform, is detected in cellular and animal AD models and is neurotoxic in hippocampal neurons. The NH2htau \u2013but not the physiological full-length protein\u2013 interacts with A\u3b2 at human AD synapses and cooperates with it in inhibiting the mitochondrial ANT-1-dependent ADP/ATP exchange. Here we show that the NH2htau also adversely affects the interplay between the mitochondria dynamics and their selective autophagic clear- ance. Fragmentation and perinuclear mislocalization of mitochondria with smaller size and density are early found in dying NH2htau-expressing neurons. The specific effect of NH2htau on quality control of mitochondria is accompanied by (i) net reduction in their mass in correlation with a general Parkin- mediated remodeling of membrane proteome; (ii) their extensive association with LC3 and LAMP1 autoph- agic markers; (iii) bioenergetic deficits and (iv) in vitro synaptic pathology. These results suggest that NH2htau can compromise the mitochondrial biology thereby contributing to AD synaptic deficits not only by ANT-1 inactivation but also, indirectly, by impairing the quality control mechanism of these organelles
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons
Functional as well as structural alterations in mitochondria size, shape and distribution are precipitating, early events in progression of Alzheimer's Disease (AD). We reported that a 20\u201322 kDa NH2-tau fragment (aka NH2htau), mapping between 26 and 230 amino acids of the longest human tau isoform, is detected in cellular and animal AD models and is neurotoxic in hippocampal neurons. The NH2htau \u2013but not the physiological full-length protein\u2013 interacts with A\u3b2 at human AD synapses and cooperates with it in inhibiting the mitochondrial ANT-1-dependent ADP/ATP exchange. Here we show that the NH2htau also adversely affects the interplay between the mitochondria dynamics and their selective autophagic clear- ance. Fragmentation and perinuclear mislocalization of mitochondria with smaller size and density are early found in dying NH2htau-expressing neurons. The specific effect of NH2htau on quality control of mitochondria is accompanied by (i) net reduction in their mass in correlation with a general Parkin- mediated remodeling of membrane proteome; (ii) their extensive association with LC3 and LAMP1 autoph- agic markers; (iii) bioenergetic deficits and (iv) in vitro synaptic pathology. These results suggest that NH2htau can compromise the mitochondrial biology thereby contributing to AD synaptic deficits not only by ANT-1 inactivation but also, indirectly, by impairing the quality control mechanism of these organelles
- …
