Differential equations associated with nonarithmetic Fuchsian groups

We describe globally nilpotent differential operators of rank 2 defined over a number field whose monodromy group is a nonarithmetic Fuchsian group. We show that these differential operators have an S-integral solution. These differential operators are naturally associated with Teichmueller curves in genus 2. They are counterexamples to conjectures by Chudnovsky--Chudnovsky and Dwork. We also determine the field of moduli of primitive Teichmueller curves in genus 2, and an explicit equation in some cases

The 2007-13 operational programmes: a preliminary assessment: Spring – Autumn 2005

A preliminary assessment of the 2007-13 operational programmes on EU cohesion policy

La esquizofrenia

A día de hoy la ciencia sigue sin encontrar la respuesta a la causa que la provoca y solo puede diagnosticarse una vez el sujeto la padece. Una alteración mental repleta de síntomas asociados cuyo remedio de momento, sigue tenieno a los fármacos y a la terapia como sus mejores aliados

cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG.

Identifying genes that are differentially expressed by Mycobacterium bovis BCG after phagocytosis by macrophages will facilitate the understanding of the molecular mechanisms of host cell-intracellular pathogen interactions. To identify such genes a cDNA-total RNA subtractive hybridization strategy has been used that circumvents the problems both of limited availability of bacterial RNA from models of infection and the high rRNA backgrounds in total bacterial RNA. The subtraction products were used to screen a high-density gridded Mycobacterium tuberculosis genomic library. Sequence data were obtained from 19 differential clones, five of which contained overlapping sequences for the gene encoding mycocerosic acid synthase (mas). Mas is an enzyme involved in the synthesis of multi-methylated long-chain fatty acids that are part of phthiocerol dimycocerosate, a major component of the complex mycobacterial cell wall. Northern blotting and primer extension data confirmed up-regulation of mas in intracellular mycobacteria and also revealed a putative extended -10 promoter structure and a long untranslated upstream region 5' of the mas transcripts, containing predicted double-stranded structures. Furthermore, clones containing overlapping sequences for furB, groEL-2, rplE and fadD28 were identified and the up-regulation of these genes was confirmed by Northern blot analysis. The cDNA-RNA subtractive hybridization enrichment and high density gridded library screening, combined with selective extraction of bacterial mRNA represents a valuable approach to the identification of genes expressed during intra-macrophage residence for bacteria such as M. bovis BCG and the pathogenic mycobacterium, M. tuberculosis

Blue Opportunities from the future: Knowledge and tools to inform sustainable growth for an integrated terrestrial, coastal and marine zone economy - a summary report

This summary brochure presents highlights of the ‘Blue Opportunities from the Future’ project.When referencing this report, please use the following citation: Day, S.A., Tolhurst, T.J., Lorenzoni, I., Johnson, M.J., Kennedy, K., Dunnett, I., Forster, J., Goodli e, R., Luisetti, T., Mengo, E., Moore, K., Parker, B., Reynolds, J., Rickards, S., and Southern, A. (2018) Blue Opportunities from the future: Knowledge and tools to inform sustainable growth for an integrated terrestrial, coastal and marine zone economy – a summary report. Marine Knowledge Exchange Network (MKEN), School of Environmental Sciences, University of East Anglia, Norwich. This project was funded by the Natural Environment Research Council (grant NE/ N017323/1) and the Economic and Social Research Council, via Impact Accelerator support to the University of East Anglia. PROJECT PARTNERS: Blue Ltd. CEFAS Coastal Partnership East Environment Agency New Anglia Local Enterprise Partnership OrbisEnergy RSPB and The Landscape Partnership We thank our project partners and participants for contributing their insights, knowledge and expertise to this research. </div

Discriminant analysis of principal components and pedigree assessment of genetic diversity and population structure in a tetraploid potato panel using SNPs

The reported narrow genetic base of cultivated potato (Solanum tuberosum) can be expanded by the introgression of many related species with large genetic diversity. The analysis of the genetic structure of a potato population is important to broaden the genetic base of breeding programs by the identification of different genetic pools. A panel composed by 231 diverse genotypes was characterized using single nucleotide polymorphism (SNP) markers of the Illumina Infinium Potato SNP Array V2 to identify population structure and assess genetic diversity using discriminant analysis of principal components (DAPC) and pedigree analysis. Results revealed the presence of five clusters within the populations differentiated principally by ploidy, taxonomy, origin and breeding program. The information obtained in this work could be readily used as a guide for parental introduction in new breeding programs that want to maximize variability by combination of contrasting variability sources such as those presented here.Fil: Deperi, Sofía Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; ArgentinaFil: Tagliotti, Martin Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; ArgentinaFil: Bedogni, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce; ArgentinaFil: Manrique Carpintero, Norma C.. Michigan State University; Estados UnidosFil: Coombs, Joseph. Michigan State University; Estados UnidosFil: Zhang, Ruofang. Inner Mongolia University; ChinaFil: Douches, David. Michigan State University; Estados UnidosFil: Huarte, Marcelo Atilio. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce; Argentin

Strategic planning for structural funds in 2007-2013. A review of strategies and programmes

Review of strategic planning for structural funds in 2007-2013 focusing on strategies and programmes