The Effect of Targeted Antibiotic Prophylaxis on Lower Urinary Tract Symptoms Following Prostate Biopsy: A Prospective Randomized Trial

Objective:Targeted antibiotic prophylaxis in prostate biopsy is recommended for patients at risk due to increased complication rates seen in recent years. Lower urinary tract symptoms (LUTS) is currently one of the most prevalent complications with a rate of more than 40%. The study examined the effects of targeted antibiotic prophylaxis on biopsy-related LUTS and to compare the results with standard prophylaxis.Materials and Methods:A total of 240 patients were included in the study, 120 of whom had been administered targeted antibiotic prophylaxis and 120 of whom had received ciprofloxacin treatment between January 2021-Januray 2023. Patients’ results before the procedure, on the 7th day, and in the first month were prospectively recorded and compared.Results:While Qmax mean values were measured as 18.3±5.1 mL/s in the targeted prophylaxis group and 17.4±4.6 mL/s in the control group (p=0.157) before the procedure, these values were found to be 14.6±3.3 mL/s and 11.7±4.1 mL/s (p<0.001) on the 7th day and 16.8 16.8±4.3 mL/s and 14.9±3.5 mL/s (p=0.013) in first month, respectively. IPSS mean scores of the groups were calculated as 16.8±4.3 mL/s and 14.9±3.5 mL/s (p=0.013) before the procedure, respectively, while these scores were found to be 18.12±6.1 and 22.97±7.4 (p<0.001) on the 7th day and 17.5±5.5 and 22.8±7.5 (p<0.001) in the first month, respectively.Conclusion:In this study, we found that targeted antibiotic prophylaxis had a significant effect on preventing biopsy-related LUTS. We believe that routine application of targeted antibiotic prophylaxis can be effective in reducing the rates of biopsy-related LUTS

Varicocele: A Review

The link between varicocele and infertility was first reported by Celsius in the first century AD, but it was not widely acknowledged until Tulloch and colleagues reported the improvement of sperm parameters in 26 of 30 patients undergoing varicocelectomy. The World Health Organization also reported that varicocele was present in 25% of patients with abnormal sperm parameters and 12% of patients with normal sperm parameters. Varicocele is the most frequently encountered surgical disease causing male infertility.</jats:p

Bipolar radiofrequency thermotherapy vs. transurethral resection of the prostate: Effect on nocturia as a result of benign prostatic obstruction

Introduction: The purpose of this study was to investigate and compare the effects of radiofrequency thermotherapy (RF) thermotherapy and transurethral resection of the prostate (TURP) on nocturia and associated quality of life in patients diagnosed with benign prostatic obstruction (BPO) under medical treatment who have complaints of persistent nocturia. Methods: The results of patients who underwent RF thermotherapy and TURP procedures between February 2019 and February 2022 were examined, and their three-month results were compared based on their uroflowmetry values, International Prostate Symptom Score (IPSS) values, nocturia frequency, and Nocturia Quality of Life Questionnaire scores. Results: While the frequency of nocturia in the RF thermotherapy group that was 4.5±1.6 before the procedure decreased to 2.3±1.4 after the procedure (p=0.002), this value in the TURP group decreased from 5.1±2.42 to 3.9±2.1 (p=0.044). RF thermotherapy was found to be more effective than TURP (p&lt;0.005). Significantly more noticeable improvements were observed in most nocturia-related next-day complaints and nocturia-related concerns in the RF thermotherapy group than the TURP group. Conclusions: It was observed that RF thermotherapy had a more acceptable effect on obstructive complaints in comparison to TURP, and it could be more effective on nocturia and associated quality of life. RF ablation treatment may be offered as an appropriate option to treat nocturia complaints in suitable patients.</jats:p