The importance of detailed epigenomic profiling of different cell types within organs.

The human body consists of hundreds of kinds of cells specified from a single genome overlaid with cell type-specific epigenetic information. Comprehensively profiling the body's distinct epigenetic landscapes will allow researchers to verify cell types used in regenerative medicine and to determine the epigenetic effects of disease, environmental exposures and genetic variation. Key marks/factors that should be investigated include regions of nucleosome-free DNA accessible to regulatory factors, histone marks defining active enhancers and promoters, DNA methylation levels, regulatory RNAs, and factors controlling the three-dimensional conformation of the genome. Here we use the lung to illustrate the importance of investigating an organ's purified cell epigenomes, and outline the challenges and promise of realizing a comprehensive catalog of primary cell epigenomes

Non-separated states from squeezed dark-state polaritons in electromagnetically-induced-transparency media

Within the frame of quantized dark-state polaritons in electromagnetically-induced-transparency media, noise fluctuations in the quadrature components are studied. Squeezed state transfer, quantum correlation, and noise entanglement between probe field and atomic polarization are demonstrated in single- and double-$\Lambda$ configurations, respectively. Even though a larger degree of squeezing parameter in the continuous variable helps to establish stronger quantum correlations, inseparability criterion is satisfied only within a finite range of squeezing parameter. The results obtained in the present study may be useful for guiding experimental realization of quantum memory devices for possible applications in quantum information and computation.Comment: 12 pages, 7 figure

Hiding Single Photons With Spread Spectrum Technology

We describe a proof-of-principal experiment demonstrating the use of spread spectrum technology at the single photon level. We show how single photons with a prescribed temporal shape, in the presence of interfering noise, may be hidden and recovered.Comment: 4 pages, 5 figures

Stationary Light Pulses in Cold Atomic Media

Stationary light pulses (SLPs), i.e., light pulses without motion, are formed via the retrieval of stored probe pulses with two counter-propagating coupling fields. We show that there exist non-negligible hybrid Raman excitations in media of cold atoms that prohibit the SLP formation. We experimentally demonstrate a method to suppress these Raman excitations and realize SLPs in laser-cooled atoms. Our work opens the way to SLP studies in cold as well as in stationary atoms and provides a new avenue to low-light-level nonlinear optics.Comment: 4 pages, 4 figure

Coherent Optical Memory with High Storage Efficiency and Large Fractional Delay

A high-storage efficiency and long-lived quantum memory for photons is an essential component in long-distance quantum communication and optical quantum computation. Here, we report a 78% storage efficiency of light pulses in a cold atomic medium based on the effect of electromagnetically induced transparency (EIT). At 50% storage efficiency, we obtain a fractional delay of 74, which is the best up-to-date record. The classical fidelity of the recalled pulse is better than 90% and nearly independent of the storage time, as confirmed by the direct measurement of phase evolution of the output light pulse with a beat-note interferometer. Such excellent phase coherence between the stored and recalled light pulses suggests that the current result can be readily applied to single photon wave packets. Our work significantly advances the technology of EIT-based optical memory and may find practical applications in long-distance quantum communication and optical quantum computation.Comment: 5 pages, 4 figure