Advocacy for women migrant workers in Malaysia through an Intersectionality lens

Analysing labour migration through the lens of intersectionality provides valuable insights into the complex identities of women migrant workers and the multiple discriminations they struggle with. Intersectionality advocates argue that only through adopting such an approach can women’s multiple discriminations be challenged. Drawing on a case study of seven NGOs and one focus group of women migrant workers in a non-western context, Malaysia, we explore how advocacy organisations understand, interpret and adopt an intersectional approach in advancing the rights of its women migrant workers. We show that there are challenges, specific to the local context, which reduces the likelihood of organisations doing so. The Malaysian experience likely has significance for similar advocacy in other Asian countries

Behaviour Intention Among Property Developer Employees to Adopt Technology Application at Workplace

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Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27

To characterize MDR Escherichia coli from bloodstream infections (BSIs) in Australia, New Zealand and Singapore.We collected third-generation cephalosporin-resistant (3GC-R) E. coli from blood cultures in patients enrolled in a randomized controlled trial from February 2014 to August 2015. WGS was used to characterize antibiotic resistance genes, MLST, plasmids and phylogenetic relationships. Antibiotic susceptibility was determined using disc diffusion and Etest.A total of 70 3GC-R E. coli were included, of which the majority were ST131 (61.4%). BSI was most frequently from a urinary source (69.6%), community associated (62.9%) and in older patients (median age 71 years). The median Pitt score was 1 and ICU admission was infrequent (3.1%). ST131 possessed more acquired resistance genes than non-ST131 (P = 0.003). Clade C1/C2 ST131 predominated (30.2% and 53.5% of ST131, respectively) and these were all ciprofloxacin resistant. All clade A ST131 (n = 6) were community associated. The predominant ESBL types were blaCTX-M (80.0%) and were strongly associated with ST131 (95% carried blaCTX-M), with the majority blaCTX-M-15. Clade C1 was associated with blaCTX-M-14 and blaCTX-M-27, whereas blaCTX-M-15 predominated in clade C2. Plasmid-mediated AmpC genes (mainly blaCMY-2) were frequent (17.1%) but were more common in non-ST131 (P

Dominance of ST131<i>Escherichia coli</i>carrying<i>bla</i>_CTX-Min patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial

Synopsis/AbstractObjectivesTo characterise multi-drug resistantEscherichia coliisolated from patients in Australia, New Zealand and Singapore with bloodstream infection (BSI).MethodsWe prospectively collected third-generation cephalosporin resistant (3GC-R)E. colifrom blood cultures obtained from patients enrolled in a randomised controlled trial. Whole genome sequencing was used to characterise antibiotic resistance genes, sequence types (STs), plasmids and phylogenetic relationships. Antibiotic susceptibility was determined using disk diffusion and Etest.ResultsA total of 70E. coliwere included, of which the majority were ST131 (61.4%). BSI was most frequently from a urinary source (69.6%), community-associated (62.9%) and in older patients (median age 71 years [IQR 64-81]). The median Pitt bacteraemia score at presentation was 1 (IQR 0-2, range 0-3) and ICU admission was infrequent (3.1%). ST131 possessed significantly more acquired resistance genes than non-ST131 (p=0.003). Clade C1/C2 ST131 predominated (30.2% and 53.5% of all ST131 respectively) and these were all resistant to ciprofloxacin. All clade A ST131 were community-associated. The predominant ESBL types wereblaCTX-M(78.6% of isolates) and were strongly associated with ST131, with the majorityblaCTX-M-15. Clade C1 was associated withblaCTX-M-14andblaCTX-M-27, whereasblaCTX-M-15predominated in clade C2. Plasmid-mediated AmpC (p-AmpC) genes (mainlyblaCMY-2) were also frequent (17.1%) but were more common with non-ST131 strains (p&lt; 0.001). The majority of plasmid replicon types were IncF.ConclusionsIn a prospective collection of 3GC-RE. colicausing BSI in the Australasian region, community-associated Clade C1/C2 ST131 predominate in association withblaCTX-MESBLs, although a significant proportion of non-ST131 strains carriedblaCMY-2.</jats:sec