831 research outputs found
An axisymmetric time-domain spectral-element method for full-wave simulations: Application to ocean acoustics
The numerical simulation of acoustic waves in complex 3D media is a key topic
in many branches of science, from exploration geophysics to non-destructive
testing and medical imaging. With the drastic increase in computing
capabilities this field has dramatically grown in the last twenty years.
However many 3D computations, especially at high frequency and/or long range,
are still far beyond current reach and force researchers to resort to
approximations, for example by working in 2D (plane strain) or by using a
paraxial approximation. This article presents and validates a numerical
technique based on an axisymmetric formulation of a spectral finite-element
method in the time domain for heterogeneous fluid-solid media. Taking advantage
of axisymmetry enables the study of relevant 3D configurations at a very
moderate computational cost. The axisymmetric spectral-element formulation is
first introduced, and validation tests are then performed. A typical
application of interest in ocean acoustics showing upslope propagation above a
dipping viscoelastic ocean bottom is then presented. The method correctly
models backscattered waves and explains the transmission losses discrepancies
pointed out in Jensen et al. (2007). Finally, a realistic application to a
double seamount problem is considered.Comment: Added a reference, and fixed a typo (cylindrical versus spherical
Narratives of ethnic identity among practitioners in community settings in the northeast of England
The increasing ethnic diversity of the UK has been mirrored by growing public awareness of multicultural issues, alongside developments in academic and government thinking. This paper explores the contested meanings around ethnic identity/ies in community settings, drawing on semi-structured interviews with staff from Children’s Centres and allied agencies conducted for a research project that examined the relationship between identity and the participation of parents/carers in services in northeast England. The research found that respondents were unclear about, especially, white ethnic identities, and commonly referred to other social categorizations, such as age, nationality, and circumstances such as mobility, when discussing service users. While in some cases this may have reflected legitimate attempts to resist overethnicizing non-ethnic phenomena, such constructions coexisted with assumptions about ethnic difference and how it might translate into service needs. These findings raise important considerations for policy and practice
Point-of-care screening for a current Hepatitis C virus infection: influence on uptake of a concomitant offer of HIV screening
Eliminating hepatitis C as a public health threat requires an improved understanding of how to increase testing uptake. We piloted point-of-care testing (POCT) for a current HCV infection in an inner-city Emergency Department (ED) and assessed the influence on uptake of offering concomitant screening for HIV. Over four months, all adults attending ED with minor injuries were first invited to complete an anonymous questionnaire then invited to test in alternating cycles offering HCV POCT or HCV+HIV POCT. Viral RNA was detected in finger-prick blood by GeneXpert. 814/859 (94.8%) questionnaires were returned and 324/814 (39.8%) tests were accepted, comprising 211 HCV tests and 113 HCV+HIV tests. Offering concomitant HIV screening reduced uptake after adjusting for age and previous HCV testing (odds ratio 0.51; 95% confidence interval [CI] 0.38–0.68; p < 0.001). HCV prevalence was 1/324 (0.31%; 95% CI 0.05–1.73); no participant tested positive for HIV. 167/297 (56.2%) POCT participants lived in the most deprived neighbourhoods in England. HCV RNA testing using finger-prick blood was technically feasible. Uptake was moderate and the offer of concomitant HIV screening showed a detrimental impact on acceptability in this low prevalence population. The findings should be confirmed in a variety of other community settings
Environmental assessment of the behavior of a BOF steel slag used in road construction : the PRECODD-ECLAIR research program
International audienceSteel production generate great amounts of by-products as steel slags. The use of Basic Oxygen Furnace slags (BOF slags) has been restrained due to insufficient volume stability, and due to the lack of environmental regulations. The purpose of the PRECODD-ECLAIR research program is to develop a behavior model based on a multi-scale physico-chemical, mechanical, hydrodynamic and ecotoxicological characterizations of a BOF slag used in a public works scenario. This paper aims at presenting the overall ECLAIR research program, the equipped experimental platform constructed using a BOF steel slag, and the first results of the slag characterization
HCV reinfection incidence and spontaneous clearance rates in HIV-positive men who have sex with men in Western Europe
BACKGROUND & AIMS: Moderate cure rates of acute hepatitis C virus (HCV) infections with pegylated interferon and ribavirin have been described in the last decade in men who have sex with men (MSM), who are also coinfected with the human immunodeficiency virus (HIV). However, a subsequent high incidence of HCV reinfections has been reported regionally in men who both clear the infection spontaneously or who respond to treatment. METHODS: Retrospective analysis of reinfections in HIV infected MSM in eight centers from Austria, France, Germany, and the UK within the NEAT network between May 2002 and June 2014. RESULTS: Of 606 individuals who cleared HCV spontaneously or were successfully treated, 149 (24.6%) presented with a subsequent HCV reinfection. Thirty out of 70 (43%) who cleared again or were successfully treated, presented with a second reinfection, 5 with a third, and one with a fourth reinfection. The reinfection incidence was 7.3/100 person-years (95% CI 6.2-8.6). We found a trend for lower incidence among individuals who had spontaneously cleared their incident infection than among individuals who were treated (Hazard ratio 0.62, 95% CI 0.38-1.02, p=0.06). Spontaneous clearance of reinfection was associated with ALT levels >1000IU/ml and spontaneous clearance of a prior infection. CONCLUSIONS: HCV reinfection is an issue of major concern in HIV-positive MSM. Prevention strategies are needed for high risk groups to reduce morbidity and treatment costs. HIV-positive MSM with a prior HCV infection should be tested every 3 to 6months for reinfection. Those who had achieved a reinfection should be tested every 3months. LAY SUMMARY: We evaluated the occurrence of HCV reinfection in HIV-positive men who have sex with men. We found an alarming incidence of 7.3/100 person-years. Prevention measures need to address this specific subgroup of patients at high risk for HCV
Observations of current rings in the Antarctic Zone at Drake Passage
Time series of current velocity and temperature from several depths at a site near the center of Drake Passage show features that can plausibly be interpreted as current rings. Between June 1975 and January 1976, five cyclonic rings from the Continental Water Boundary and one anticyclonic ring from the Polar Front passed over the site. The diameters of the rings varied from 30 km to 130 km, and all of them extended vertically to a depth of at least 2500 m. The rings exhibited maximum spin velocities of about 20 cm sec−1 at 1000 m depth and 10 cm sec−1 at 2500 m. Their translatory motion, which was toward the north at about 4 cm sec−1, contained a westward component relative to the ambient flow. The magnitude of the westward component suggests that it may have resulted from an interaction between rings and the sea floor, which slopes downward to the northeast at the mooring site. The total available mechanical energy of the rings (kinetic plus potential) varied from 6.2 × 1013 j in the smallest ring to 9.9 × 1014 in the largest. The available heat, relative to the Antarctic Zone, was several orders of magnitude larger: −3.0 × 1017 j for the smallest ring and −3.6 × 1018 j for the largest. The numbers indicate that current rings may play an important role in dissipating the kinetic energy of the circumpolar fronts and that they may be responsible for a significant poleward flux of heat in the Southern Ocean
Dental Abnormalities and Early Diagnosis of Hyperphosphatasemia
Dental hard tissue abnormalities have never been described as part of the symptoms associated with hyperphosphatasemia. Fourteen teeth obtained from a young man, who had a mild form of hyperphosphatasemia, were analyzed using scanning electron microscopy (SEM), secondary ion mass spectroscopy (SIMS), X-ray diffraction (XRD), and infrared (IR) spectroscopy. SEM revealed a thin enamel, presenting a prismatic structure with many pits, and atypical cementum and dentin showing numerous resorption areas. The X-ray diffractograms revealed poorly crystallinehydroxyapatite associated with α-tricalcium phosphate and magnesium hydroxide phases. SIMS data showed high Ca concentrations: 40.5 weight % {wt%; standard deviation (SD) = 0.13) and 42.5 wt% (SD = 1.03) in enamel and dentin respectively, and high Ca/P weight ratios: 2.28 in the enamel, 2.65 in the dentin. The lack of crystallinity may be linked to the high content of proteins and magnesium adsorbed onto apatite.
This study demonstrates the need for thorough radiographical and biological investigations for skeletal abnormalities, even in the absence of systemic symptoms, when generalized dental abnormalities of both enamel and dentin are observed
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An analysis of upwelling off the south-east Arabian coast during the summer monsoon
A method is described for determining the absolute dynamic
topography of the sea surface. Using hydrographic and wind data obtained
in 1963, the surface topography and the horizontal and vertical
mass transports off the southeast Arabian coast during the summer
monsoon are calculated. As indicated by the calculations, upwelling
occurs throughout a region extending at least 400 km offshore and
paralleling the Arabian coast for over 1000 km. Upwelling is most
intense in a narrow band adjacent to the coast. Because of the great
breadth of the upwelling zone, the upwelled water is supplied from
levels considerably deeper than those observed elsewhere in coastal
upwelling areas
Challenging the field: Bourdieu and men's health
©2014 Macmillan Publishers Ltd. This article considers how understandings of health promotion with men may be assisted by engagement with Bourdieu's theoretical work. The article outlines leading concepts within Bourdieu's work on 'field', 'habitus' and 'capital'; considers subsequent critical debates among gender, feminist and sociological theorists around structure and agency; and links these to discussions within men's health. A particular focus concerns structural disruption of, and movement of social actors between, 'fields' such as family, work and leisure settings. The article examines, through Bourdieu's critical legacy, whether such disruption establishes conditions for transformative reflexivity among men in relation to previously held dispositions (habitus), including those inflected by masculinities, that affect men's health practices. Recent work within Bourdieu's heritage potentially facilitates a re-framing of understandings of men's health practices. The article specifically explores masculine ambivalence within accounts of reflexivity, identities and practice, and considers how social and symbolic (masculine) capital are in play. Implications of Bourdieu's leading concepts for theorising settings-focused approaches to men's health promotion are exemplified with reference to a men's health project in a football stadium leisure setting. The article considers the benefits and challenges of applying gendered critical insights drawing on Bourdieu's work to men's health promotion, and discusses emerging theoretical dilemmas
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